Results 81 to 90 of about 1,835,674 (303)

Temperature-based tuning of magnetic particle separation by on-chip free-flow magnetophoresis [PDF]

open access: yes, 2009
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009)   +6 more
core  

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Aerodynamic Sensitivity Analysis for a Wind Turbine Airfoil in an Air-Particle Two-Phase Flow

open access: yesApplied Sciences, 2019
In this paper, the Navier-Stokes equations coupled with a Lagrangian discrete phase model are described to simulate the air-particle flows over the S809 airfoil of the Phase VI blade, the NH6MW25 airfoil of a 6 MW wind turbine blade and the NACA0012 ...
Tongqing Guo   +4 more
doaj   +1 more source

Flow separation in shock wave boundary layer interactions at hypersonic speeds [PDF]

open access: yes
An assessment is presented for the experimental data on separated flow in shock wave turbulent boundary layer interactions at hypersonic and supersonic speeds.
Hamed, A.
core   +1 more source

Lattice Boltzmann Simulation of Non-Ideal Fluids

open access: yes, 1995
A lattice Boltzmann scheme able to model the hydrodynamics of phase separation and two-phase flow is described. Thermodynamic consistency is ensured by introducing a non-ideal pressure tensor directly into the collision operator.
A. J. Liu   +21 more
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Experimental study on Header-orifice Vapor-liquid Separation Unit using Zeotropic Mixture

open access: yesZhileng xuebao
Vapor-liquid separation technology can achieve enhanced heat transfer while reducing pressure drop. Vapor-liquid separation unit is the key to achieve efficient vapor-liquid separation.
CHEN Guanghao   +6 more
doaj  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

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