Results 51 to 60 of about 6,048,963 (333)
Research on ladle nozzle clogging during continuous casting of non-oriented electrical steel with high silicon [PDF]
To figure out the reason causing ladle nozzle clogging during CC (continuous casting) of a non-oriented electrical steel with high silicon (or HNO for short) and get a method to address it, this paper studied the theoretical calculation of flow rates ...
Wei Kong, Da-Qiang Cang
doaj +1 more source
Single-cell western blotting. [PDF]
To measure cell-to-cell variation in protein-mediated functions, we developed an approach to conduct ∼10(3) concurrent single-cell western blots (scWesterns) in ∼4 h.
Herr, Amy E +5 more
core +2 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
In view of the problem that the static characteristics of the slide valve can affect the performance of the hydraulic servo system,the software simulation method is mainly used to analyze the pressure,flow velocity and flow distribution law of the ...
WU Yueneng +5 more
doaj +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Microfluidic devices offer well-defined physical environments that are suitable for effective cell seeding and in vitro three-dimensional (3D) cell culture experiments.
Manoela Neves +5 more
doaj +1 more source
3D seismic evidence of internal structure within Tampen Slide deposits on the North Sea Fan : are chaotic deposits that chaotic? [PDF]
The seismic character of slide deposits is typically described as structureless or chaotic. However, 3D seismic data from the northern flank of the North Sea Fan reveal recognizable internal, penetrative structures within the Tampen Slide deposits.
Evans, D. +3 more
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Calculation of lubricant flow in the slide bearing of the aviation engine reducer
A method has been developed for calculating the pressure distribution in a cylindrical slide bearing. We present the process of designing a heavy-duty slide bearing as a component of the reduction gearbox of a bypass turbojet engine as the object of our ...
M. V. Siluyanova, A. О. Fertikov
doaj +1 more source
Robust Simulation for Hybrid Systems: Chattering Path Avoidance [PDF]
The sliding mode approach is recognized as an efficient tool for treating the chattering behavior in hybrid systems. However, the amplitude of chattering, by its nature, is proportional to magnitude of discontinuous control.
Aljarbouh, Ayman, Caillaud, Benoit
core +5 more sources

