Results 161 to 170 of about 20,948 (256)

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). I. Treatments in preclinical and early clinical development

Epilepsia, EarlyView.
Abstract Over the last 34 years, the Eilat Conference on New Antiepileptic Drugs and Devices has provided an interactive forum for stakeholders to discuss investigational and recently licensed treatments for seizures and epilepsy. The Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII) took place in Madrid, Spain, on May 3 ...
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Calcium chloride and/or sodium selenite: an effective strategy for extending vase life and alleviating stem bending in gerbera "Stanza" flowers. [PDF]

BMC Plant Biol
Youssef SM, El-Serafy RS.
europepmc   +1 more source

Epilepsy‐associated SCN2A‐L1342P mutation drives network hyperexcitability and widespread transcriptomic changes in human cortical organoids

Epilepsia, EarlyView.
Abstract Objective SCN2A pathogenic mutations, such as the recurrent heterozygous Nav1.2‐L1342P, are monogenic causes of epilepsy. In this human‐induced pluripotent stem cell–derived model system, we aim to investigate the molecular and cellular mechanisms underlying SCN2A‐L1342P‐associated pathology. Methods Using a human male induced pluripotent stem
Maria I. Olivero‐Acosta, Morgan Robinson, Zhefu Que, Zaiyang Zhang, Karen V. Salazar‐Salazar, Hope Elizabeth Harlow, Vinayak Shankar, Seoyeon Hong, Muhan Wang, Conrad M. Otterbacher, Hina Kadono, Manasi Halurkar, Harish Kothandaraman, Nadia Atallah Lanman, Trang Nguyen, Kyle Wettschurack, Benjamin Zirkle, Layan Yunis, Ningren Cui, Xiaoling Chen, Jingliang Zhang, Jiaxiang Wu, William C. Skarnes, Chongli Yuan, Feng Guo, Megan Abbott, Yang Yang   +26 more
wiley   +1 more source

Clinician Perspectives on Barriers and Enablers to Autism‐Affirming Eating Disorder Care

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Autistic people with an eating disorder (ED) report more negative experiences of ED treatment and are at greater risk of requiring higher intensity services. Current ED treatment options do not fully meet underpinning drivers of autistic people's experiences of EDs.
Emy Nimbley, Amelia Austin, Kate Tchanturia, Kai Thomas, Catherine R. G. Jones, Karri Gillespie‐Smith, Fiona Duffy   +6 more
wiley   +1 more source

Inconsistent Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail: A Comparative Analysis of Results From Four Different Study Designs

Environmental Toxicology and Chemistry, EarlyView.
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers, Elena Legrand, Emily Boulanger, Niladri Basu, Jessica D. Ewald, Paula Henry, Markus Hecker, Jianguo Xia, Natalie Karouna‐Renier, Doug Crump, Jessica Head   +10 more
wiley   +1 more source

Cost of fruiting, size regulation, and senescence in a long-lived geophyte. [PDF]

PLoS One
Thomson JD, Andrews DF.
europepmc   +1 more source

Screening Interactive Impact of Dietary Bivalent Metallic Ions on S. anguivi Bioactive Components: Bitterness Attenuation and Antioxidant Activities Augmentation

Food Chemistry International, EarlyView.
Unpleasant bitterness associated with bioactive components of S. anguivi, a vegetal fruit with many therapeutics functionalities, was attenuated on interaction with dietary bivalent metallic ions with concomitant augmentation of antioxidant activity. ABSTRACT Bioactive components of S.
Daramola Bode
wiley   +1 more source

Controlled and Modified Atmospheres Combined with 1-MCP Improve Postharvest Quality and Suppress <i>Botrytis cinerea</i> in Cut Roses (<i>Rosa hybrida</i> L.). [PDF]

Plants (Basel)
İnce E, Akbudak N, İnce O.
europepmc   +1 more source

Ancient Schwannoma in the Nasal Cavity—A Rare Case Report With Brief Literature Review

Eye &ENT Research, EarlyView.
Shikhar Chohan, Annmy Jose, Sufian Zaheer   +2 more
wiley   +1 more source

Strategies for Identification and Mitigation of Sanguinarine in Mustard Oil Adulterated by Argemone—A Comprehensive Review

Food Chemistry International, EarlyView.
Sanguinarine, a toxic alkaloid present in argemone, can lead to epidemic dropsy or chronic diseases through DNA intercalation and immune system suppression. Regulatory efforts face challenges due to economic motivations for adulteration as well as technical, social, and infrastructure barriers.
Gururaj Pejavara Narayana, Subhangi Panigrahi, Suresh Kumar Kalakandan, Hema Vincent, Ashish Rawson   +4 more
wiley   +1 more source