Results 11 to 20 of about 9,635 (184)

Comparative efficacy of selenoureido carbonic anhydrase inhibitors and azole antifungal drugs against clinical isolates of Malassezia pachydermatis. [PDF]

Vet Dermatol
Background – Malassezia pachydermatis (MP) is implicated in severe dermatitis and otitis externa (OE) of companion animals and recently gained attention for its increasing resistance to azole compounds. For this reason, developing novel therapeutic strategies is of great interest. In a previous work, we used reference yeast isolates to evaluate several
Spadini C, Mezzasalma N, Odigie AE, Angeli A, Carta F, Selleri S, Gandolfo E, Taddei S, Franceschi V, Minesso S, Supuran CT, Cabassi CS.   +11 more
europepmc   +2 more sources

S1‐Leitlinie Onychomykose

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 21, Issue 6, Page 678-694, June 2023., 2023
Zusammenfassung Die Onychomykose ist eine Pilzinfektion des Nagelorgans und betrifft sowohl Finger‐ als auch Zehennägel. Sie wird in Europa vor allem durch Dermatophyten verursacht. Die Diagnostik erfolgt mittels direktmikroskopischer, kultureller und/oder molekularer Methoden aus Nagelmaterial (Nagelspäne).
Pietro Nenoff, Dieter Reinel, Peter Mayser, Dietrich Abeck, Guntram Bezold, Philipp P. Bosshard, Jochen Brasch, Georg Daeschlein, Isaak Effendy, Gabriele Ginter‐Hanselmayer, Yvonne Gräser, Gudrun Hamm, Ulrich Hengge, Uta‐Christina Hipler, Peter Höger, Alexandra Kargl, Annette Kolb‐Mäurer, Constanze Krüger, Bartosz Malisiewicz, Johannes Mayer, Hagen Ott, Uwe Paasch, Martin Schaller, Silke Uhrlaß, Miriam Zidane   +24 more
wiley   +1 more source

Frequently acquired drugs in neonatal intensive care and their physical compatibility

Acta Paediatrica, Volume 111, Issue 12, Page 2307-2314, December 2022., 2022
Abstract Aim Incompatibility of intravenous drugs is dangerous and therefore undesirable. The aim of this study was to identify the most commonly acquired intravenous drugs in five neonatal intensive care units and test these for compatibility. Methods The most frequently acquired drugs in five key hospitals in the South‐Eastern district of Norway for ...
Katerina Nezvalova‐Henriksen, Tone Huseby Holm, Niklas Nilsson, Inge Kjønniksen, Ingunn Tho   +4 more
wiley   +1 more source

Synergistic effect of low‐frequency ultrasound and antibiotics on the treatment of Klebsiella pneumoniae pneumonia in mice

Microbial Biotechnology, Volume 15, Issue 11, Page 2819-2830, November 2022., 2022
In the present in vivo study, we provide evidence showing that LFU can improve the efficacy of meropenem (MEM) or amikacin (AMK) in Kp pneumonia model. LFU combined with antibiotics significantly improved the survival state of mice, decrease the counts per second (CPS), accelerated the clearance of bacteria and reduced inflammatory injury of lung.
Kaicheng Yan, Tianli Yang, Juan Xu, Liuhan Dong, Jin Wang, Yun Cai   +5 more
wiley   +1 more source

Pharmakologie der Januskinase‐Inhibitoren – Teil 1: Pharmakokinetik

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 20, Issue 11, Page 1485-1500, November 2022., 2022
Zusammenfassung Der Einsatz von Januskinase‐Inhibitoren zur Therapie chronisch‐entzündlicher Erkrankungen etabliert sich zunehmend als Behandlungsoption in mehreren Indikationen. Um den klinischen Einsatz effizient zu gestalten, sind pharmakologische Kenntnisse zum JAK/STAT‐Signalweg zu den Besonderheiten der Pharmakokinetik der einzelnen Arzneistoffe ...
Adina Eichner, Johannes Wohlrab
wiley   +1 more source

Low dose apixaban as secondary prophylaxis of venous thromboembolism in cancer patients – 30 months follow‐up

Journal of Thrombosis and Haemostasis, Volume 20, Issue 5, Page 1166-1181, May 2022., 2022
Abstract Background There are no data on the effect of low‐dose anticoagulation as secondary prophylaxis for venous thromboembolism (VTE) in cancer patients. We assessed the efficacy and safety of low‐dose apixaban for 30 months, after initial 6 months of full‐dose treatment.
Trine‐Lise Larsen, Herish Garresori, Jorunn Brekke, Tone Enden, Hege Frøen, Eva Marie Jacobsen, Petter Quist‐Paulsen, Alina Carmen Porojnicu, Anne Hansen Ree, Dag Torfoss, Elin Osvik Velle, Hilde Skuterud Wik, Waleed Ghanima, Per Morten Sandset, Anders Erik Astrup Dahm   +14 more
wiley   +1 more source

Antimicrobial Properties of Strychnos phaeotricha (Loganiaceae) Liana Bark Secondary Metabolites at the Interface of Nanosilver Particles and Nanoencapsulation by Chitosan Transport Vehicles

Journal of Nanomaterials, Volume 2022, Issue 1, 2022., 2022
In this study, Strychnos phaeotricha liana bark extract was used as a metabolite container both on the surface of metallic nanosilver and encapsulated by a chitosan polymer. The plant extract was able to reduce Ag+ into Ag0 efficiently, and the encapsulation rate was determined.
Armel Florian Tchangou Njiemou, Awawou Paboudam Gbambie, Simone Veronique Fannang, Antoine Vayarai Manaoda, Vasily Gvilava, Alex Spieß, Gildas Fonye Nyuyfoni, Nelie Alida Mepoubong Kegne, Agnes Antoinette Ntoumba, Philippe Belle Ebanda Kedi, Bertin Sone Enone, Francis Ngolsou, Jean Yves Sikapi Fouda, Joel Olivier Avom Mbeng, Mesode Nnange Akweh, Armelle Michelle Houatchaing Kouemegne, Daniel Aurelien Yana, Geordamie Chimi, Alex Vincent Somba, Vandi Deli, Emmanuel Nnanga Nga, Francois Eya’ane Meva, Christoph Janiak, Lavinia Balan   +23 more
wiley   +1 more source

Real clinical impact of drug–drug interactions of immunosuppressants in transplant patients

Pharmacology Research &Perspectives, Volume 9, Issue 6, December 2021., 2021
Abstract The main objective was to determine the prevalence of real drug–drug interactions (DDIs) of immunosuppressants in transplant patients. We conducted a prospective, observational 1‐year study at a tertiary hospital, including all transplanted patients.
Ana Isabel Gago‐Sánchez, Pilar Font, Manuel Cárdenas, María Dolores Aumente, José Ramón Del Prado, Miguel Ángel Calleja   +5 more
wiley   +1 more source

„Indische“ Trichophyton mentagrophytes‐Stämme mit reduzierter Itraconazol‐Empfindlichkeit in Deutschland

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 19, Issue 12, Page 1723-1728, December 2021., 2021
Zusammenfassung Wir nehmen die publizierten und drei eigene Fälle von Tinea durch „indische“ Trichophyton (T.) mentagrophytes‐Stämme vom ITS‐Genotyp VIII mit reduzierter Itraconazol‐Empfindlichkeit bei der Mutation c.1342G>A im SQLE‐Gen zum Anlass, über diesen Erreger in Deutschland zu berichten.
Jochen Brasch, Yvonne Gräser, Vera Beck‐Jendroscheck, Karen Voss, Kaspar Torz, Grit Walther, Thomas Schwarz   +6 more
wiley   +1 more source

Prevalence and Fluconazole Susceptibility Profile of Candida spp. Clinical Isolates in a Brazilian Tertiary Hospital in Minas Gerais, Brazil

Anais da Academia Brasileira de Ciências, 2015
Candidiasis has become an important concern for clinical practice, especially with the increasing incidence of immunocompromised patients. In this scenario, the development resistance to fluconazole presents a challenge for treating these opportunistic ...
Athayde Neves-Junior, Ana Carolina Cartágenes-Pinto, Débora A.S. Rocha, Leandro F. Reis de Sá, Maria de Lourdes Junqueira, Antonio Ferreira-Pereira   +5 more
doaj   +1 more source