Results 91 to 100 of about 106,245 (320)

Creation and assessment of a clinical predictive calculator and mortality associated with Candida krusei bloodstream infections [PDF]

, 2018
Background Candida krusei bloodstream infection (CK BSI) is associated with high mortality, but whether this is due to underlying comorbidities in affected patients or the organism itself is unknown.
Hsueh, Kevin, Kronen, Ryan, Lin, Charlotte, Powderly, William G, Spec, Andrej   +4 more
core   +2 more sources

A chromosome 4 trisomy contributes to increased fluconazole resistance in a clinical isolate of Candida albicans

Microbiology, 2017
Candida albicans is an important opportunistic fungal pathogen capable of causing both mucosal and disseminated disease. Infections are often treated with fluconazole, a front-line antifungal drug that targets the biosynthesis of ergosterol, a major ...
Matthew Z. Anderson, A. Saha, A. Haseeb, R. Bennett   +3 more
semanticscholar   +1 more source

Candida albicans  Genotyping and Relationship of Virulence Factors with Fluconazole Tolerance in Infected Pediatric Patients

Infection and Drug Resistance, 2022
Ghada El-Saeed Mashaly,1 Mayada Sabry Zeid2 1Medical Microbiology and Immunology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt; 2Infectious Diseases and Malnutrition, Pediatrics Department, Faculty of Medicine, Mansoura University,
Mashaly GE, Zeid MS
doaj  

EUCAST Technical Note on fluconazole [PDF]

Clinical Microbiology and Infection, 2008
Contains fulltext : 70468.pdf (Publisher’s version ) (Closed access)
Rodriquez Tudela, J.L., Donnelly, J.P., Arendrup, M.C., Arikan, S., Barchiesi, F., Bille, J., Chryssanthou, E., Cuenca-Estrella, M., Danaoui, E., Denning, D.W., Fegeler, W., Gaustad, P., Klimko, N., Lass-Florl, C., Moore, C., Richardson, M., Schmalreck, A., Stenderup, J., Velegraki, A., Verweij, P.E.   +19 more
openaire   +3 more sources

Bloodstream yeast infections: a 15-month survey [PDF]

, 2009
A 15-month survey of 412 bloodstream yeast isolates from 54 Belgian hospitals was undertaken. Candida albicans was the most common species (47.3%) followed by C. glabrata (25.7%), C. parapsilosis (8.0%), C. tropicalis (6.8%) and Saccharomyces cerevisiae (
Detandt, M, Nolard, N, Swinne, D, Van Rooij, Pascale   +3 more
core   +1 more source

Eradication of Candida albicans persister cell biofilm by the membranotropic peptide gH625 [PDF]

, 2020
Biofilm formation poses an important clinical trouble due to resistance to antimicrobial agents; therefore, there is an urgent demand for new antibiofilm strategies that focus on the use of alternative compounds also in combination with conventional ...
D'Alterio, A., de Alteriis, E., De Natale, A., Falanga, A., Galdiero, E., Galdiero, S., Guida, M., Lombardi, L., Siciliano, A.   +8 more
core   +1 more source

Comparative Hepatotoxicity of Fluconazole, Ketoconazole, Itraconazole, Terbinafine, and Griseofulvin in Rats

Journal of Toxicology, 2017
Oral ketoconazole was recently the subject of regulatory safety warnings because of its association with increased risk of inducing hepatic injury. However, the relative hepatotoxicity of antifungal agents has not been clearly established.
S. Khoza, Ishmael Moyo, Denver Ncube
semanticscholar   +1 more source

Fungal biofilm resistance [PDF]

, 2012
Fungal biofilm infections have become increasingly recognised as a significant clinical problem. One of the major reasons behind this is the impact that these have upon treatment, as antifungal therapy often fails and surgical intervention is required ...
Rajendran, Ranjith, Ramage, Gordon, Sherry, Leighann, Williams, Craig   +3 more
core   +4 more sources

Heteroresistance to Fluconazole Is a Continuously Distributed Phenotype among Candida glabrata Clinical Strains Associated with In Vivo Persistence

mBio, 2016
Candida glabrata causes persistent infections in patients treated with fluconazole and often acquires resistance following exposure to the drug. Here we found that clinical strains of C.
R. Ben-Ami, Offer Zimmerman, Talya Finn, S. Amit, A. Novikov, N. Wertheimer, Mor N. Lurie-Weinberger, J. Berman   +7 more
semanticscholar   +1 more source

A Systematic Review of Synthetic and Anticancer and Antimicrobial Activity of Quinazoline/Quinazolin‐4‐one Analogues

ChemistryOpen, EarlyView.
Quinazoline represents an important class of heterocycles with diverse medicinal and pharmacological significance. This review systematically examines scholarly efforts toward understanding different synthetic pathways emphasizing the role of metal and non‐metal catalysts including some miscellaneous reagents employed in the synthesis of quinazoline ...
Neha Manhas, Gobind Kumar, Sanjeev Dhawan, Talent Makhanya, Parvesh Singh   +4 more
wiley   +1 more source