Results 101 to 110 of about 61,779 (245)

Antimicrobial photodynamic therapy in Candida spp. biofilms: In vitro and in vivo protocols

Photochemistry and Photobiology, EarlyView.
This review addresses the critical challenges in translating in vitro antimicrobial photodynamic therapy protocols to in vivo models, with a particular focus on the hurdles of standardization. The vast diversity in photosensitizers and light parameters across different target cells and models requires a rigorous optimization process.
Lívia Mara Alves Figueiredo‐Godoi, Ana Júlia Barbosa Tomé, Cristina Kurachi   +2 more
wiley   +1 more source

The Association of Pretransplant CD4 Count With Post‐Kidney Transplant Infectious Outcomes Among Persons With HIV

Transplant Infectious Disease, EarlyView.
In this multi‐center study comparing persons with HIV with pre‐kidney transplant CD4 < 350 cells/µL to those with ≥ 350 cells/µL, we found no difference in relative risk of infection in the first year‐post kidney transplant, 5‐year graft survival, and 5‐year overall survival.
Rebecca H. Burns, Sara Booth, Christin Rogers Marks, Christine M. Durand, Jonathan Hand, Maheen Z. Abidi, Maricar Malinis, Brittany Barnaba, Martha Pavlakis, Douglas Krakower, Carolyn D. Alonso, Audrey Le‐Mahajan   +11 more
wiley   +1 more source

Enhanced contact activity of fluconazole in association with antioxidants against fluconazole-resistant organisms.

, 2002
Fluconazole alone does not demonstrate any contact activity against resistant organisms. Phenolic antioxidants, such as butylated hydroxyanisole, appear to promote fluconazole activity resulting in the killing of 10(4) cfu/mL of 11 resistant Candida ...
SIMONETTI, Nicola, SIMONETTI, Giovanna, VILLA, Adelaide, G. Simonetti   +3 more
core   +1 more source

Invasive Fungal Infections in Heart Transplants: A 10‐Year, Single Centre Retrospective Cohort Study From Subtropical Australia

Transplant Infectious Disease, EarlyView.
In this 10‐year retrospective cohort study of heart transplant recipients in subtropical Australia, we characterize the incidence and microbiological profile of invasive fungal infections, highlighting the underappreciated burden of late‐onset and non‐Aspergillus mold infections and the potential underdiagnosis of polymicrobial disease.
Angus Lane, Karen Hay, John McNamara, Alex Chaudhuri, Andrew Burke, Robert Horvath, Maryam Khorramshahi Bayat, Kanthi Vemuri   +7 more
wiley   +1 more source

Combining Fluconazole with Benzo[a]phenoxazine Derivatives as a Promising Strategy Against Fluconazole-Resistant Candida Species [PDF]

The rise in non-albicans Candida species, exhibiting unpredictable antifungal resistance, complicates treatment and contributes to the growing threat of invasive, life-threatening infections.
Costa-Barbosa, Augusto, Sampaio, Paula, Pacheco, Maria Inês Costa, Gonçalves, M. Sameiro T., M. Sameiro T. Gonçalves, Maria João Sousa, Sousa, Maria João, Maria Inês Pacheco, Augusto Costa-Barbosa, Paula Sampaio, Pereira-Silva, Patrícia, Bárbara Guimarães, Guimarães, Bárbara, Patrícia Pereira-Silva   +13 more
core   +1 more source

Treatment of Canine Atopic Dermatitis: Updated Guidelines From the International Committee on Allergic Diseases of Animals (ICADA)

Veterinary Dermatology, EarlyView.
ABSTRACT Background Canine atopic dermatitis (cAD) is a genetically, aetiologically, immunologically and clinically complex disease requiring both individualised immediate and long‐term management. Objectives These updated guidelines from the International Committee on Allergic Diseases of Animals (ICADA) aim to substantially revise previous ...
Ralf S. Mueller, Frane Banovic, Emmanuel Bensignor, Domenico Santoro, Tim Nuttall   +4 more
wiley   +1 more source

Insights into current coccidioidomycosis therapeutic pathways

Antimicrobial Agents and Chemotherapy
Coccidioidomycosis is a systemic fungal infection caused by Coccidioides immitis and Coccidioides posadasii, which are endemic to the Southwestern United States and parts of Mexico, Central, and South America. While oral fluconazole is widely recommended
Brent Edwards, Rebecca Ripperton, Adeleine Tilley, Daniel B. Chastain, George R. Thompson, Andrés F. Henao-Martínez   +5 more
doaj   +1 more source

Flucytosine-fluconazole cross-resistance in purine-cytosine permease-deficient Candida lusitaniae clinical isolates: indirect evidence of a fluconazole uptake transporter

, 2003
An unusual interaction between flucytosine and fluconazole was observed when a collection of 60 Candida lusitaniae clinical isolates was screened for cross-resistance.
Noël, Thierry, Paumard, Patrick, Villard, Jean, Chastin, Christiane, François, Fabienne, Brèthes, Daniel   +5 more
core   +1 more source

hERG1 channels and potential therapeutics for long QT syndrome

The Journal of Physiology, EarlyView.
Abstract figure legend Prolonged QT results from hERG1 channel dysfunction. (A) Physiological anterograde trafficking of hERG1 channels to the plasma membrane, leading to a normal electrocardiogram. (B) Prolonged QT results from the presence of fewer hERG1 channels on the plasma membrane due to decreased anterograde trafficking or reduced function due ...
Elizabeth H. Schneider, Kelly A. Aromolaran, Michael C. Sanguinetti, Ademuyiwa S. Aromolaran   +3 more
wiley   +1 more source

Candidacidal effect of fluconazole and chlorhexidine released from acrylic polymer

, 2013
Objectives: To investigate the efficacy and rate of killing of a fluconazole- or chlorhexidine-impregnated polymeric delivery system against fluconazole-susceptible and -resistant Candida albicans and fluconazole-resistant Candida glabrata. Methods: Poly(
Salim, N., Silikas, N., Moore, C., Satterthwaite, J.; id_orcid, Richardson, Rautemaa-Richardson; id_orcid   +4 more
core   +1 more source