Results 81 to 90 of about 55,654 (235)

Comparison of antifungal effects of an experimental fluconazole mouthwash and nystatine mouthwash: An in vitro study

مجله دانشکده دندانپزشکی اصفهان, 2013
Introduction: Treatment of oral candidiasis with mouthwashes has several advantages. The aim of the present study was to evaluate the clinical efficacy of a new fluconazole suspension on the Candida albicans and compare its effects with those of nystatin.
Nader Navabi, Ehsan Momeni, Amin Ayatollahi, Payam Khazaeli, Abbas Pardakhti   +4 more
doaj  

Physiologically based pharmacokinetic modeling of fluconazole: interpretation of gender-dependent pharmacokinetics and cytochrome P450 inhibition

Frontiers in Pharmacology
The accurate prediction of clinical drug–drug interactions (DDIs) in modeling analysis relies on the fraction of metabolism and transport of the substrate drugs and on the inhibitory potency and plasma exposure of index inhibitors.
Kazuya Ishida, Rakshit Sanjay Tanna, Jesse Yang, Yurong Lai   +3 more
doaj   +1 more source

Diagnosis and management of neutropenia in adults: Expert guidance

British Journal of Haematology, EarlyView.
Severe neutropenia can result from decreased production of neutrophil precursors in the bone marrow, as in the case of severe congenital neutropenia, or from increased utilization of neutrophils or their accelerated destruction as for drug‐induced neutropenia or autoimmune neutropenia. Severe chronic neutropenia increases susceptibility to bacterial or
Karl Welte, Cornelia Zeidler, Julia Skokowa, Sabine Mellor‐Heineke, Audrey Anna Bolyard, David Dale   +5 more
wiley   +1 more source

Rifampin-Fluconazole Interaction in Critically ILL Patients [PDF]

, 1995
Objective: To report the influence of rifampin coadministration on the pharmacokinetics of fluconazole in 2 critically ill patients. Case Summaries: The pharmacokinetics of fluconazole are reported in 5 patients in the intensive care unit (ICU), 2 of ...
Helen M Crowe, Richard Quintiliani, David P Nicolau, Charles H Nightingale   +3 more
core   +1 more source

Quantitation of ergosterol content and gene expression profile of ERG11 gene in fluconazole-resistant Candida albicans

Current Medical Mycology, 2017
Background and Purpose: The frequency of opportunistic fungal infections in immunocompromised patients, especially by Candida species, has sharply increased in the last few decades.
Fahimeh Alizadeh, Alireza Khodavandi, Sara Zalakian   +2 more
doaj  

High dose fluconazole in salvage therapy for HIV-uninfected cryptococcal meningitis

BMC Infectious Diseases, 2018
Background The 2010 Infectious Diseases Society of America (IDSA) guidelines for management of cryptococcal diseases recommend high dose fluconazole (≥ 800 mg/day), either alone or with other antifungal drugs, as alternative anticryptococcal choices. But
Hua-Zhen Zhao, Rui-Ying Wang, Xuan Wang, Ying-Kui Jiang, Ling-Hong Zhou, Jia-Hui Cheng, Li-Ping Huang, Thomas Stephen Harrison, Li-Ping Zhu   +8 more
doaj   +1 more source

Risk Factors for Fluconazole-Resistant Candidemia [PDF]

, 2010
Previous studies have sought to determine the risk factors associated with candidemia caused by non-albicans Candida spp. or with potentially fluconazole-resistant Candida spp. (C. glabrata and C. krusei). Non-albicans Candida strains are a heterogeneous
Emilio García-cabrera, Jose ́ Garnacho-montero, Ortiz-Leyba, Carlos, Carlos Ortiz-leyba, Garnacho-Montero, José, Diaz-Martin, Ana, Aznar-Martin, Javier, Ana Díaz-martín, Perez de Pipaon, Maite Ruiz, García-Cabrera, Emilio, Cisneros, José Miguel, Maite Ruiz, Jose ́ M. Cisneros, Javier Aznar-martín, Hernandez-Caballero, Clara   +14 more
core   +1 more source

Emergence of Trichophyton indotineae in Switzerland (2014–2025): Clinical analysis and antifungal susceptibility

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Trichophyton indotineae is an emerging dermatophyte associated with chronic, recalcitrant dermatophytosis and terbinafine resistance due to squalene epoxidase (SQLE) mutations. We analyzed clinical characteristics, antifungal susceptibility profiles, SQLE mutations, and treatment outcomes of cases diagnosed in ...
Annabel H. Lechner, Dennis D. Arnold, Philipp P. Bosshard   +2 more
wiley   +1 more source

INVESTIGATION OF THE EFFECT OF GENTAMICIN TO FLUCONAZOLE IN FLUCONAZOLE RESISTANT ISOLATES OF CANDİDA SPP. [PDF]

, 2022
Amaç: Antifungal ilaçlara karşı gelişen direnç, antifungallerin etkinliğinin azalmasına katkıda bulunmaktadır. Bu nedenle kullanılmakta olan ilaçların başka moleküller ile kombine kullanımları, yeni ilaç keşfine kıyasla daha gerçekçi bir yöntem olduğu ...
Tikveşli, Melek, Genç, Bahar, Ökten, Suzan   +2 more
core  

Analysis of the risk factors associated with bloodstream infections caused by Candida parapsilosis in pediatric patients and the determinants of fluconazole non-susceptibility: a retrospective 15-year cohort study

BMC Infectious Diseases
Background In recent decades, infections caused by C.parapsilosis have been increasingly reported, particularly strains of C.parapsilosis that are non-susceptible to fluconazole. Aims We aimed to evaluate candidemia episodes caused by C. parapsilosis (CP)
Zumrut Sahbudak Bal, Sema Yildirim Arslan, Gizem Guner Ozenen, Gülizar Turan, Kübra Cebeci, Ulgen Celtik, Gulhadiye Avcu, Nihal Karadas, Gulcihan Ozek, Miray Karakoyun, Dilek Yesim Metin, Suleyha Hilmioglu Polat   +11 more
doaj   +1 more source