Results 71 to 80 of about 61,779 (245)

The activity of echinocandins, amphotericin B and voriconazole against fluconazole-susceptible and fluconazole-resistant Brazilian Candida glabrata isolates

open access: yes, 2012
The extensive use of azole antifungal agents has promoted the resistance of Candida spp to these drugs. Candida glabrata is a problematic yeast because it presents a high degree of primary or secondary resistance to fluconazole. In Brazil, C.
Milene Silva Antunes   +6 more
core   +1 more source

Ocular and cutaneous infection due to Curvularia pseudobrachyspora in an immunosuppressed dog: Case report and in vitro antimycotic susceptibilities

open access: yesAustralian Veterinary Journal, EarlyView.
A 3‐year‐old male Border Collie diagnosed with immune‐mediated dermatopathy, managed with tapering prednisolone and cyclosporine, developed rapidly progressive ocular signs and additional cutaneous lesions. Histopathology, mycological culture, polymerase chain reaction and sequencing confirmed intraocular and cutaneous infection due to Curvularia ...
T Brasil‐Ervedosa   +4 more
wiley   +1 more source

Vaginal azoles versus oral fluconazole in treatment of recurrent vulvovaginal candidiasis [PDF]

open access: yes
Background: Vulvovaginal candidiasis (VVC) is a fungal infection of the vagina and vulva. It is usually caused by Candida albicans, however, occasionally other candida species are responsible. The optimal treatment of VVC has not yet been defined.
فردی آذر, زهرا   +3 more
core  

Fluconazole and Ibuprofen Combination: A Potential Treatment for Mucosal Candidiasis

open access: yesMedical Laboratory Journal, 2020
Background and objectives: The incidence of drug-resistant candidiasis has increased dramatically. This study aimed to evaluate antifungal effects of fluconazole alone and in combination with ibuprofen on isolates from patients with mucosal candidiasis.  
Tahere Shamoushaki, Leila Fozouni
doaj  

Emergence of Trichophyton indotineae in Switzerland (2014–2025): Clinical analysis and antifungal susceptibility

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Trichophyton indotineae is an emerging dermatophyte associated with chronic, recalcitrant dermatophytosis and terbinafine resistance due to squalene epoxidase (SQLE) mutations. We analyzed clinical characteristics, antifungal susceptibility profiles, SQLE mutations, and treatment outcomes of cases diagnosed in ...
Annabel H. Lechner   +2 more
wiley   +1 more source

Comparison of antifungal effects of an experimental fluconazole mouthwash and nystatine mouthwash: An in vitro study

open access: yesمجله دانشکده دندانپزشکی اصفهان, 2013
Introduction: Treatment of oral candidiasis with mouthwashes has several advantages. The aim of the present study was to evaluate the clinical efficacy of a new fluconazole suspension on the Candida albicans and compare its effects with those of nystatin.
Nader Navabi   +4 more
doaj  

Mitochondrial iron homeostasis is required for azole tolerance in Candida albicans

open access: yesThe FEBS Journal, EarlyView.
In Candida albicans, the deletion of MRS4, which encodes a mitochondrial iron importer, abolishes fluconazole tolerance and increases cidality during cotreatment with the iron chelator BPS, without altering MIC or synergy. Fluconazole‐treated mutants exhibit increased mitochondrial depolarisation, fragmentation and reduced mitochondrial density.
Wouter Van Genechten   +4 more
wiley   +1 more source

Determination of fluconazole susceptibility in Schizosaccharomyces pombe

open access: yes, 2021
Fluconazole inhibits ergosterol biosynthesis and this deficiency prevents fungal growth by disrupting the structure of the fungal cell membrane. 3 42 genes that were fully sensitive and 33 genes that were semi-sensitive to 50 µg/ml fluconazole, 11 ...
Türk, Ayşegül   +4 more
core  

Feasibility and clinical outcomes of routine point‐of‐care screening for opportunistic infections among people with advanced HIV disease in Guyana

open access: yesHIV Medicine, EarlyView.
Abstract Objectives We evaluated the feasibility and outcomes of implementing comprehensive Point‐of‐care (POC) opportunistic infections (OIs) screening among people with Advanced HIV disease (AHD) in Guyana. Methods We conducted a prospective multicentre cohort study across seven sites between February 2024 and March 2025.
Antonio Camiro‐Zúñiga   +13 more
wiley   +1 more source

Quantitation of ergosterol content and gene expression profile of ERG11 gene in fluconazole-resistant Candida albicans

open access: yesCurrent Medical Mycology, 2017
Background and Purpose: The frequency of opportunistic fungal infections in immunocompromised patients, especially by Candida species, has sharply increased in the last few decades.
Fahimeh Alizadeh   +2 more
doaj  

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