Results 51 to 60 of about 55,654 (235)

The transcription factor Rpn4 activates its own transcription and induces efflux pump expression to confer fluconazole resistance in Candida auris

mBio, 2023
The emergence and nosocomial spread of the multidrug-resistant Candida auris pose a severe public health threat. Most C. auris clinical isolates are fluconazole resistant.
Eve W. L. Chow, Yabing Song, Jinxin Chen, Xiaoli Xu, Jianbin Wang, Kun Chen, Jiaxin Gao, Yue Wang   +7 more
doaj   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). I. Treatments in preclinical and early clinical development

Epilepsia, EarlyView.
Abstract Over the last 34 years, the Eilat Conference on New Antiepileptic Drugs and Devices has provided an interactive forum for stakeholders to discuss investigational and recently licensed treatments for seizures and epilepsy. The Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII) took place in Madrid, Spain, on May 3 ...
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Treatment of cryptococcal meningitis in KwaZulu-Natal, South Africa. [PDF]

, 2010
BACKGROUND: Cryptococcal meningitis (CM) remains a leading cause of death for HIV-infected individuals in sub-Saharan Africa. Improved treatment strategies are needed if individuals are to benefit from the increasing availability of antiretroviral ...
Martin Dedicoat, Josephine V J Lightowler, Portia Mutevedzi, Lightowler Josephine V. J., Richard J Lessells, Newell, Marie-Louise, Marie-Louise Newell, Lightowler, Josephine VJ, Cooke, Graham S, Cooke Graham S., Mutevedzi Portia, Lessells Richard J., Mutevedzi, Portia, Lessells, Richard J, Dedicoat Martin, Dedicoat, Martin, Graham S Cooke, Newell Marie-Louise   +17 more
core   +1 more source

Lack of fluconazole effects on human chemosensation [PDF]

, 2022
S.13-20Objective: Drug effects on the function of smell and taste are occasionally mentioned in prescription information however, most originate from anecdotal reports without even distinguishing between gustatory or olfactory deteriorations.
Lötsch, J., Oertel, B.G., Hummel, T., Huynh, T.T.   +3 more
core   +1 more source

Cytotoxicity of fluconazole on canine dental pulp-derived stem cells

Journal of Oral Biology and Craniofacial Research, 2020
Objective: In order to use fluconazole as an antifungal in cell cultures, we evaluated its possible cytotoxic effects and its influence on the proliferation and viability of canine dental pulp-derived stem cells (cDPSCs).
Paulo Henrique Utumi, Letícia Fracaro, Felipe Yukio Ishikawa Fragoso, Dayane Mayumi Miyasaki, Paula Joly dos Santos, Lidiane Maria Boldrini-Leite, Paulo Roberto Slud Brofman, José Ademar Villanova, Jr., Alexandra Cristina Senegaglia   +8 more
doaj   +1 more source

Fluconazole-resistant Candida parapsilosis: A new emerging threat in the fungi arena

Frontiers in Fungal Biology, 2022
Candida parapsilosis is a leading cause of invasive candidiasis in southern Europe, Latin America and Asia. C. parapsilosis has been mostly considered susceptible to triazoles, but fluconazole resistance is on the rise in some countries.
Pilar Escribano, Pilar Escribano, Jesús Guinea, Jesús Guinea, Jesús Guinea   +4 more
doaj   +1 more source

Unlocking the Multifunctional Properties of Litsea cubeba Essential Oil: Composition, Antimicrobial, Antibiofilm and Insecticidal Activities

Flavour and Fragrance Journal, EarlyView.
Unveiling the chemical and biological properties of Litsea cubeba essential oil. ABSTRACT Litsea cubeba essential oil (LCEO) is recognised for its broad spectrum of biological activities, including antimicrobial and insecticidal effects, making it a promising natural alternative to synthetic agents.
Miroslava Kačániová, Minhang Qiao, Alessandro Bianchi, Joel Horacio Elizondo‐Luevano, Anis Ben Hsouna, Rania Ben Saad, Zhaojun Ban, Li Li, Jian Lou, Wissem Mnif, Stefania Garzoli   +10 more
wiley   +1 more source

Multifunctional Properties of Wintergreen (Gaultheria procumbens) Essential Oil: Antimicrobial, Antibiofilm, and Insecticidal Effects

Flavour and Fragrance Journal, EarlyView.
Unveiling the potential of Wintergreen (Gaultheria procumbens) essential oil. ABSTRACT This study investigated the antimicrobial, antibiofilm, and insecticidal properties of wintergreen (Gaultheria procumbens L.) essential oil (GPEO). The EO was chemically characterized by GC–MS, confirming methyl salicylate as the predominant compound (99.3%).
Miroslava Kačániová, Minhang Qiao, Alessandro Bianchi, Joel Horacio Elizondo‐Luevano, Anis Ben Hsouna, Rania Ben Saad, Zhaojun Ban, Li Li, Jian Lou, Wissem Mnif, Stefania Garzoli   +10 more
wiley   +1 more source

Fluconazole resistance in Candida species: a current perspective [PDF]

, 2017
Elizabeth L Berkow, Shawn R Lockhart Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA Abstract: Candida albicans and the emerging non-albicans Candida spp.
Lockhart SR, Berkow EL
core  

FLUCONAZOLE: A REVIEW [PDF]

, 2016
Fluconazole is a bis-triazole antifungal drug with novel pharmacokinetic properties (metabolic stability, relatively high water solubility) which contribute to its therapeutic activity.
Addetla Sagarika*, Boreda Sowmya, Aprajitha Bhatnagar , Dr. Kameswari
core   +1 more source