Results 41 to 50 of about 42,420 (122)

Quantitation of ergosterol content and gene expression profile of ERG11 gene in fluconazole-resistant Candida albicans

open access: yesCurrent Medical Mycology, 2017
Background and Purpose: The frequency of opportunistic fungal infections in immunocompromised patients, especially by Candida species, has sharply increased in the last few decades.
Fahimeh Alizadeh   +2 more
doaj  

Phenotypic and genomic characterization of azole resistance in Portuguese Candida parapsilosis isolates

open access: yesFrontiers in Fungal Biology
IntroductionCandida parapsilosis is a clinically important etiological agent of systemic infections associated with hospital outbreaks, which prevalence has been increasing in the last decade.
Alexandru-Marian Papuc   +9 more
doaj   +1 more source

Fluconazole induces rapid high-frequency MTL homozygosis with microbiological polymorphism in Candida albicans

open access: yesJournal of Microbiology, Immunology and Infection, 2017
Background: Candida albicans, a common fungal pathogen that can cause opportunistic infections, is regarded as an apparently asexual, diploid fungus. A parasexual cycle was previously found between homozygotes with opposite mating type-like loci (MTLa/α)
Tsong-Yih Ou   +10 more
doaj   +1 more source

An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris

open access: yesNature Communications, 2020
The fungal pathogen Candida auris is resistant to multiple drugs including the common antifungal fluconazole. Here, Iyer et al. identify a compound that potentiates fluconazole activity against C.
Kali R. Iyer   +21 more
doaj   +1 more source

Correlation between ERG11 Gene Mutations and Fluconazole Resistance in Candida albicans Strains Isolated from Rasht in Years 2015-2016 [PDF]

open access: yesMajallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2017
Background: Candida albicans as an opportunistic fungal pathogen in human causes candidiasis. The widespread use of azoles has led to the increase of azole resistance in Candida albicans isolates.
Saeedeh Balabandi   +2 more
doaj  

In vitro activities of antifungal agents alone and in combination against fluconazole-susceptible and -resistant strains of Candida dubliniensis

open access: yesBrazilian Journal of Infectious Diseases
In the present study we used two groups of Candida dubliniensis strains: one containing fluconazole-susceptible clinical isolates and another containing fluconazole-resistant laboratory derivative from the former to examine the changes on susceptibility ...
Liliane Alves Scheid   +4 more
doaj   +1 more source

Fluconazole (Diflucan®) [PDF]

open access: yesInfectious Diseases in Obstetrics and Gynecology, 1995
Hollier, Lisa M., Cox, Susan M.
openaire   +2 more sources

Lipase Gene Expression of Resistant and Sensitive Candida Albicans to Fluconazole Isolated from Patients Suffering from Oral Candidiasis and Vaginal Candidiasis

open access: yesMedical Laboratory Journal, 2015
Background and Objective: With the development of drug resistance in strains of fungi, there is a considerable resistance of Candida albicans strains to fluconazole. Molecular studies are developing to determine the relationship of such a drug resistance
Nasrollahi Omran, A   +3 more
doaj  

Retinal toxicity of intravitreally injected plain and liposome formulation of fluconazole in rabbit eye

open access: yesIndian Journal of Ophthalmology, 2006
Purpose: Candidal endophthalmitis is a sight-threatening ocular infection that most frequently occurs as a complication of candidemia. Fluconazole has been effective against Candida albicans in various animal models.
Velpandian Thirumurthy   +4 more
doaj  

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