Results 41 to 50 of about 106,245 (320)

Emergence of clonal fluconazole-resistant Candida parapsilosis clinical isolates in a multicentre laboratory-based surveillance study in India

open access: yesJournal of Antimicrobial Chemotherapy, 2019
Objectives The emergence of fluconazole resistance in Candida parapsilosis healthcare-associated infections has recently been increasingly reported. Antifungal susceptibility profiles and mechanisms of fluconazole resistance in C.
Ashutosh Singh   +10 more
semanticscholar   +1 more source

Current status of antihistamines repurposing for infectious diseases [PDF]

open access: yesarXiv, 2022
Objectives. This review gathers information on the potential role of antihistamines as anti-infective agents and identifies gaps in research that have impaired its applicability in human health. Methods. The literature search encompassed MEDLINE, PubMed and Google Scholar from 1990 to 2022. Results.
arxiv  

A natural histone H2A variant lacking the Bub1 phosphorylation site and regulated depletion of centromeric histone CENP-A foster evolvability in Candida albicans. [PDF]

open access: yes, 2019
Eukaryotes have evolved elaborate mechanisms to ensure that chromosomes segregate with high fidelity during mitosis and meiosis, and yet specific aneuploidies can be adaptive during environmental stress.
Brimacombe, Cedric A   +8 more
core   +3 more sources

Adhesive Properties and Sensitivity to Antifungal Drugs of Candida Albicans, Which Are Released From Patients of Gastroenterological Profile with Candidiasis of the Mucosa of the Upper Part of the Digestive Tract [PDF]

open access: yes, 2016
Candida albicans were released from 146 loci from 89 patients in order to perform the investigation. The fourth stage of contamination by Candida albicans in the scrape from the tongue and candidiasis of the esophagus or /and the stomach during ...
Kushnirenko, I. (Inessa)
core   +2 more sources

Associations between low- and high-dose oral fluconazole and pregnancy outcomes: 3 nested case–control studies

open access: yesCanadian Medical Association Journal, 2019
Background: While topical azoles are the first-line treatment for fungal infections, oral fluconazole is frequently used during pregnancy. We aimed to assess the effect of exposure to low and high doses of fluconazole during pregnancy on the occurrence ...
A. Bérard   +6 more
semanticscholar   +1 more source

Sphingolipid Inhibitors as an Alternative to Treat Candidiasis Caused by Fluconazole-Resistant Strains

open access: yesPathogens, 2021
Candida species are fungal pathogens known to cause a wide spectrum of diseases, and Candida albicans and Candida glabrata are the most common associated with invasive infections.
Rodrigo Rollin-Pinheiro   +6 more
doaj   +1 more source

Fluconazole Penetration into the Pancreas [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2000
ABSTRACT Because of antibiotic prophylaxis for necrotizing pancreatitis, the frequency of fungal superinfection in patients with pancreatic necrosis is increasing. In this study we analyzed the penetration of fluconazole into the human pancreas and in experimental acute pancreatitis.
Claudia Issenegger   +8 more
openaire   +3 more sources

Repurposing of terconazole as an anti Trypanosoma cruzi agent [PDF]

open access: yes, 2019
Trypanosoma cruzi is the causative agent of Chagas disease, a parasitic infection endemic in Latin America. Currently there are no effective treatments for the chronic phase of the disease, when most patients are diagnosed, therefore the development of ...
Martínez Sayé, Melisa Soledad   +4 more
core   +1 more source

Fluconazole Resistance in Isolates of Uncommon Pathogenic Yeast Species from the United Kingdom

open access: yesAntimicrobial Agents and Chemotherapy, 2019
The triazole drug fluconazole remains one of the most commonly prescribed antifungal drugs, both for prophylaxis in high-risk patients and also as a second-line treatment option for invasive Candida infections.
A. Borman   +7 more
semanticscholar   +1 more source

Synergistic Effects of Amiodarone and Fluconazole on Candida tropicalis Resistant to Fluconazole [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2013
ABSTRACT There have recently been significant increases in the prevalence of systemic invasive fungal infections. However, the number of antifungal drugs on the market is limited in comparison to the number of available antibacterial drugs. This fact, coupled with the increased frequency of cross-resistance, makes it necessary to
Thalles B. Grangeiro   +11 more
openaire   +3 more sources

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