Results 81 to 90 of about 110,241 (334)
Cytotoxicity of fluconazole on canine dental pulp-derived stem cells
Journal of Oral Biology and Craniofacial Research, 2020 Objective: In order to use fluconazole as an antifungal in cell cultures, we evaluated its possible cytotoxic effects and its influence on the proliferation and viability of canine dental pulp-derived stem cells (cDPSCs).
Paulo Henrique Utumi +8 more
doaj +1 more source
The Surgical Infection Society revised guidelines on the management of intra-abdominal infection [PDF]
, 2017 Background: Previous evidence-based guidelines on the management of intra-abdominal infection (IAI) were published by the Surgical Infection Society (SIS) in 1992, 2002, and 2010. At the time the most recent guideline was released, the plan was to update
Chang, Phillip K +11 more
core +3 more sources
Synergistic Effect of Fluconazole and Calcium Channel Blockers against Resistant Candida albicans
PLoS ONE, 2016 Candidiasis has increased significantly recently that threatens patients with low immunity. However, the number of antifungal drugs on the market is limited in comparison to the number of available antibacterial drugs.
Shuyuan Liu +5 more
semanticscholar +1 more source
Drug Discovery Applications of Nitroso (Hetero)Arene Derivatives
ChemPlusChem, EarlyView.Nitroso (hetero)aromatic compounds are bioactive molecules with antiviral, anticancer, neuroprotective, and antimicrobial properties. This review highlights their mechanisms of action—oxidative stress, DNA damage, and enzyme inhibition—alongside synthesis, structure–activity relationships, and toxicity challenges, offering insight into their ...
Silvia Roscales, Aurelio G. Csáky
wiley +1 more source
BMC Infectious Diseases, 2016 BackgroundCandidemia is an increasing problem in tertiary care hospitals worldwide. Here, we report the first outbreak of candidemia caused by fluconazole-resistant C.
H. M. Pinhati +5 more
semanticscholar +1 more source
Flavour and Fragrance Journal, EarlyView.Chemical and biological investigation of Elettaria cardamomum EO. ABSTRACT Cardamom, a highly valued spice, is predominantly cultivated in Guatemala and India. The plant is notable for its potent essential oil and unique, pleasant aroma. One of the many potential uses of cardamom essential oil lies within the culinary industry.
Miroslava Kačániová +8 more
wiley +1 more source
Frequent premature ventricular contractions induced by fluconazole: A case report
IDCasesIntroduction: Fluconazole is commonly used to treat and prevent fungal infections caused by Candida and Cryptococcus species. Although there have been reports of fatal arrhythmias induced by fluconazole, such as torsades de pointes, there have been ...
Kumi Tamura +2 more
doaj +1 more source
SWL-1 Reverses Fluconazole Resistance in Candida albicans by Regulating the Glycolytic Pathway
Frontiers in Microbiology, 2020 Candida albicans is a ubiquitous clinical fungal pathogen. Prolonged use of the first-line antifungal agent fluconazole (FLC) has intensified fungal resistance and limited its effectiveness for the treatment of fungal infections.
Xiao-Ning Li +13 more
doaj +1 more source
Frontiers in Microbiology, 2016 Candida glabrata is a major pathogenic yeast in humans that is known to rapidly acquire resistance to triazole and echinocandin antifungal drugs. A mutator genotype (MSH2 polymorphism) inducing a mismatch repair defect has been recently proposed to be ...
S. Dellière +11 more
semanticscholar +1 more source
Interdisciplinary Medicine, EarlyView.Although most cancer cells rely on aerobic glycolysis, Oxidative phosphorylation (OXPHOS) remains essential for their survival, proliferation, and metastasis. With the emergence of OXPHOS‐targeted drugs, its therapeutic potential is becoming increasingly evident.
Keke Chen +5 more
wiley +1 more source