Results 121 to 130 of about 62,274 (300)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Fluctuation theory of ambipolar diffusion in a magneto-plasma

, 1969
Fluctuation theory of ambipolar diffusion in ...
Tchen, C. M.
core  

Queues and Lévy fluctuation theory

, 2015
The book provides an extensive introduction to queueing models driven by Lévy-processes as well as a systematic account of the literature on Lévy-driven queues.
Mandjes, M., Mandjes, Michel, Dębicki, Krzysztof, Dębicki, K.   +3 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Rescaled Range Analysis and Detrended Fluctuation Analysis: Finite Sample Properties and Confidence Intervals

We focus on finite sample properties of two mostly used methods of Hurst exponent H estimation—rescaled range analysis (R/S) and detrended fluctuation analysis (DFA).
Ladislav Krištoufek
core  

Photoacoustic fluctuation imaging: theory and application to blood flow imaging

, 2020
Photoacoustic fluctuation imaging, which exploits randomness in photoacoustic generation, provides enhanced images in terms of resolution and visibility, as compared to conventional photoacoustic images.
Bastien Arnal (1651111), Emmanuel Bossy (3961847), Guillaume Godefroy (9389783), Sergey Vilov (4446736)   +3 more
core   +1 more source

Numerical simulation study of lower hybrid wave scattering full-wave solution in scrap-off layer

He jishu
BackgroundLower hybrid current drive (LHCD) is one of the main auxiliary heating and current driving methods for Tokamak, and studies have shown that the boundary parasitics effect of lower hybrid (LH) wave in scrap-off layer (SOL) significantly ...
YANG Jinghe, DING Bojiang, WU Chenbin, LI Miaohui, WANG Mao, LIU Liang, YAN Guanghou   +6 more
doaj   +1 more source

Theoretical and Experimental Study on Echo Fluctuation Suppression of a Cirrus Cloud by Millimeter Wave MIMO Radar

International Journal of Antennas and Propagation, 2019
The scattering properties of nonspherical particles can be approximately computed by equivalent spherical theory. The scattering properties of ice particles were approximately computed by Rayleigh approximation because the sizes of the ice particles are ...
Jinhu Wang, Junxiang Ge, Ming Wei, Hongbin Chen, Zexin Yang, Yushu Ren, Qilin Zhang, Hao Chen   +7 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source