Results 111 to 120 of about 62,274 (300)

Surface Area Estimation: Replacing the Brunauer-Emmett-Teller Model with the Statistical Thermodynamic Fluctuation Theory. [PDF]

Langmuir, 2022
Shimizu S, Matubayasi N.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Fluorescence fluctuation analysis of Arabidopsis thaliana somatic embryogenesis receptor-like kinase and brassinosteroid insensitive 1 receptor ologomerization.

, 2008
Receptor kinases play a key role in the cellular perception of signals. To verify models for receptor activation through dimerization, an experimental system is required to determine the precise oligomerization status of proteins within living cells ...
Vries, S.C., de, Russinova, Eugenia, Visser, Antonie J.W.G., Shah, K., Vries, S.C., de Vries, Sacco C, Hink, M.A., de Vries, S.C., Shah, Khalid, Hink, Mark A, Visser, A.J.W.G., Russinova, E.T., Visser, Antonie JWG, Hink, Mark A., de Vries, Sacco C., Russinova, E.   +15 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Perpetual Options and Canadization Through Fluctuation Theory [PDF]

, 2000
In this article it is shown that one is able to evaluate the price of perpetual calls, puts, Russian and integral options directly as the Laplace transform of a stopping time of an appropriate diusion using standard uctuation theory.
Kyprianou, A., Pistorius, M.
core  

Observed Fluctuation Enhancement and Departure from WKB Theory in Sub-Alfvénic Solar Wind

The Astrophysical Journal Letters
Using Parker Solar Probe data from orbits 8 through 17, we examine fluctuation amplitudes throughout the critical region where the solar wind flow speed approaches and then exceeds the Alfvén wave speed, taking account of various exigencies of the plasma
David Ruffolo, Panisara Thepthong, Peera Pongkitiwanichakul, Sohom Roy, Francesco Pecora, Riddhi Bandyopadhyay, Rohit Chhiber, Arcadi V. Usmanov, Michael Stevens, Samuel Badman, Orlando Romeo, Jiaming Wang, Joshua Goodwill, Melvyn L. Goldstein, William H. Matthaeus   +14 more
doaj   +1 more source

Doping asymmetry of superconductivity coexisting with antiferromagnetism in spin fluctuation theory

New Journal of Physics, 2015
We generalize the theory of Cooper-pairing by spin excitations in the metallic antiferromagnetic state to include situations with electron and/or hole pockets.
W Rowe, I Eremin, A T Rømer, B M Andersen, P J Hirschfeld   +4 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Microscopic fluctuation theory (mFT) for interacting Poisson processes

, 2019
International audienceWhile the Macroscopic Fluctuation Theory (MFT) is a renormalized theory in the hydrodynamic limit based on a space-time local Lagrangian that is Gaussian with respect to the empirical current, C. Maes, K. Netocny and B.
Monthus, Cecile
core   +1 more source