Results 91 to 100 of about 10,229 (223)

A simple and robust method for connecting small-molecule drugs using gene-expression signatures [PDF]

, 2008
Interaction of a drug or chemical with a biological system can result in a gene-expression profile or signature characteristic of the event. Using a suitably robust algorithm these signatures can potentially be used to connect molecules with similar ...
B Efron, CC Ting, J Frasor, J Lamb, JD Storey, JJ Chen, JS Warrington, KB Glaser, L Tian, M Lee, N Fujimoto, N Sathyamoorthy, PA Horwitz, R Januchowski, S McHugh, SD Zhang, Shu-Dong Zhang, ST Matalon, Timothy W Gant, VW Armstrong, Y Chen   +20 more
core   +5 more sources

Infants With Congenital Adrenal Hyperplasia Are at Risk for Hypercalcemia, Hypercalciuria, and Nephrocalcinosis [PDF]

, 2017
In a retrospective study, most young children with CAH had at least one episode of hypercalcemia, whereas a smaller percentage was found to have hypercalciuria and/or ...
Imel, Erik A., Nailescu, Corina, Schoelwer, Melissa J., Viswanathan, Vidhya, Wilson, Amy   +4 more
core   +1 more source

Effect of stress doses of hydrocortisone on S-100B vs. interleukin-8 and polymorphonuclear elastase levels in human septic shock [PDF]

, 2005
Stress doses of hydrocortisone a re known to have immunomodulatory effects in patients with hyperdynamic septic shock. The prognosis correlates with the presence and severity of septic encephalopathy. However, neurological evaluation is influenced by the
Anderson, Annane, Astudillo, Barie, Barie, Bastos, Bertsch, Blomquist, Bollaert, Bolton, Bolton, Bone, Briegel, Briegel, Briegel, Briegel, Danielson, Donato, Eidelman, Endo, Haimoto, Herrmann, Hollenberg, Hund, Hund, Jonsson, Keh, Lindner, Marshall, Metinko, Munck, Mussack, Mussack, Pelinka, Pelinka, Rosen, Schwarz, Stanimirovic, Usui, Vincent, Waage, Weiss, Westaby, Wheeler, Wiesmann, Wunderlich, Young   +46 more
core   +2 more sources

Corticotherapy for traumatic brain-injured Patients - The Corti-TC trial: study protocol for a randomized controlled trial

Trials, 2011
Background Traumatic brain injury (TBI) is a main cause of severe prolonged disability of young patients. Hospital acquired pneumonia (HAP) add to the morbidity and mortality of traumatic brain-injured patients. In one study, hydrocortisone for treatment
Asehnoune Karim, Roquilly Antoine, Sebille Véronique, group The Corti-TC trial   +3 more
doaj   +1 more source

Exercise induced collapse: neurocardiogenic syncope [PDF]

, 2009
This issue of eMedRef provides information to clinicians on the pathophysiology, diagnosis, and therapeutics of exercise induced collapse caused by neurocardiogenic ...
Chang, Tony
core  

Cardiovascular abnormalities and impaired exercise performance in adolescents with congenital adrenal hyperplasia [PDF]

, 2015
Context: Patients with classic Congenital Adrenal Hyperplasia (CAH) are treated with lifelong glucocorticoids (GCS). Cardiovascular (CV) and metabolic effects of such therapy in adolescents have never been quantified.
Alessio, Maria, Arcopinto, Michele, Capalbo, Donatella, Cittadini, Antonio, De Paulis, Amato, Improda, Nicola, Isidori, Andrea, Lenzi, Andrea, Marra, ALBERTO MARIA, Salerno, Mariacarolina, Salzano, Andrea   +10 more
core   +1 more source

Recurrent nocturnal hypoglycaemia as a cause of morning fatigue in treated Addison’s disease – Favourable response to dietary management: A case report [PDF]

, 2015
Background: Addison’s disease, or primary adrenal insufficiency, is often associated with reduced well-being and fatigue despite use of currently recommended adrenal hormone replacement. Hypoglycaemia is a known manifestation of glucocorticoid deficiency,
Clifton, Peter M, Petersen, Kristina S, Rushworth, R Louise, Torphy, David J   +3 more
core   +2 more sources

Fludrocortisone for Treatment of Intradialytic Hypotension: Case Report and Review of Literature [PDF]

, 2021
Nasser Mikhail
openalex   +1 more source

Aldosterone synthase deficiency associated with a CYP11B2 variant of uncertain significance: Case report and literature review

Journal of Clinical and Translational Endocrinology Case Reports
Congenital aldosterone synthase deficiency (ASD) is a rare autosomal recessive condition that causes isolated primary hypoaldosteronism. It has been associated with different pathogenic mutations of the CYP11B2 gene.
Bayan AlNassir, Hessah AlOtaibi
doaj   +1 more source

The use of desoxycorticosterone pivalate in dogs with hypoadrenocorticism : a retrospective study of eight cases [PDF]

, 2018
In this article, the use of desoxycorticosterone pivalate is retrospectively reviewed in eight dogs with primary hypoadrenocorticism, presented at the Small Animal Department of Ghent University.
Albers, Maai, Daminet, Sylvie, Defauw, Pieter, Mortier, Femke   +3 more
core