Case Report: Type II Bartter syndrome with a novel KCNJ1 variant in a premature neonate presenting with features of salt-wasting congenital adrenal crisis and pseudo-hypoaldosteronism [PDF]
Frontiers in PediatricsIntroductionBartter syndrome (BS) is a rare group of inherited renal tubulopathies. Diagnosis of BS type II is challenging in the neonatal period as its clinical findings and biochemical features may mimic that of adrenal crisis and pseudo ...
Heung-Ching Tsui +7 more
doaj +2 more sources
StAR Protein Deficiency in Clinical Practice: A Case Series From Saudi Arabia. [PDF]
Case Rep EndocrinolObjectives Steroidogenic acute regulatory (StAR) protein deficiency is a rare autosomal recessive disorder that disrupts steroid hormone biosynthesis, resulting in congenital adrenal hyperplasia (CAH) and variations in sexual development. However, limited data is available in Saudi Arabia.
Alabduljabbar A +5 more
europepmc +2 more sources
Genetic Insights and Lifelong Management of Aldosterone Synthase Deficiency: A Case of Hyperreninemic Hypoaldosteronism. [PDF]
Clin Case RepABSTRACT Aldosterone synthase deficiency is a rare cause of neonatal salt‐wasting and failure to thrive. Routine newborn electrolyte screening after 5 days of life is vital for early detection and prevention of life‐threatening crises. Genetic confirmation enables targeted fludrocortisone therapy, ensuring favorable growth and developmental outcomes.
Ahmed MMH +4 more
europepmc +2 more sources
Fludrocortisone Induces Aortic Pathologies in Mice
Biomolecules, 2022 Background and Objective: In an experiment designed to explore the mechanisms of fludrocortisone-induced high blood pressure, we serendipitously observed aortic aneurysms in mice infused with fludrocortisone.
Dien Ye +12 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2022 BackgroundLow-dose steroids are known to increase arterial pressure during septic shock through restoration of vasopressor response to norepinephrine. However, their effects on cardiac performance and ventriculo-arterial coupling (VAC) have never been ...
François Bagate +15 more
doaj +1 more source
Fix or Adapt? Rethinking the Management of Complex Autonomic Dysfunction in an Older Adult Following Orthopedic Surgery. [PDF]
Geriatr Gerontol IntGeriatrics &Gerontology International, Volume 25, Issue 12, Page 1962-1964, December 2025.
De Louche CD, Palliyage S.
europepmc +2 more sources
Use of Deoxycorticosterone Pivalate by Veterinarians: A Western European Survey
Veterinary Sciences, 2021 This study aims to gather knowledge about the use of deoxycorticosterone pivalate (DOCP) by Western European Veterinarians (WEV) in dogs with typical hypoadrenocorticism.
Rita Rebocho +8 more
doaj +1 more source
Endocrine Connections, 2021 Objective: Treatment of classic congenital adrenal hyperplasia (CAH) is necessary to compensate for glucocorticoid/mineralocorticoid deficiencies and to suppress androgen excess.
Heike Hoyer-Kuhn +12 more
doaj +1 more source
Post-Tuberculosis Adrenal Crisis in a Young Boy: A Case Report. [PDF]
Clin Case RepABSTRACT An adrenal crisis should be considered in children with a history of tuberculosis who present with shock, hypoglycemia, and hyperpigmentation. Even years after successful treatment, TB can cause irreversible adrenal damage leading to primary adrenal insufficiency. Early recognition and prompt glucocorticoid replacement are lifesaving.
Haleem A +5 more
europepmc +2 more sources
Primary adrenal insufficiency - Addison's disease
Journal of Education, Health and Sport, 2022 Introduction and purpose Addison's syndrome is defined as primary adrenal insufficiency, the symptoms of which result from hormonal deficiencies: glucocorticosteroids, mineralocorticosteroids and androgens.
Jakub Metelski +4 more
doaj +1 more source