Results 11 to 20 of about 8,686 (179)

Association of mortality with fludrocortisone addition to hydrocortisone treatment among septic shock patients: a propensity score matching analysis

Frontiers in Medicine, 2023
BackgroundSeveral clinical trials of corticosteroids have been carried out in the treatment of septic shock, however, the therapeutic effect of the most widely used hydrocortisone is still controversial, and no studies have directly compared ...
Xiaoxiao Cheng, Zhiqin Fu, Yiting Liu, Xiaoyu Zheng, Tianyang Hu   +4 more
doaj   +2 more sources

Performance of renin assays in selecting fludrocortisone dose in children with adrenal disorders

Endocrine Connections
Children with salt-wasting adrenal insufficiency are managed with glucocorticoid and mineralocorticoid replacement. Measurement of renin activity or concentration alongside blood electrolyte levels is used to monitor the adequacy of mineralocorticoid ...
Timothy J Morris, Andrew Whatmore, Laura Hamilton, Beverly Hird, Eric S Kilpatrick, Lesley Tetlow, Peter Clayton   +6 more
doaj   +2 more sources

Access to fludrocortisone and to hydrocortisone in children with congenital adrenal hyperplasia in the WHO Eastern Mediterranean Region: it takes a village…

BMJ Global Health, 2021
Congenital adrenal hyperplasia (CAH), if untreated, carries high morbidity and mortality. A higher incidence of CAH is expected in countries where consanguinity is common, such as in the countries of the WHO Eastern Mediterranean Region (EMRO).
, Asma Deeb, Jean-Pierre Chanoine, Jamal Raza, Amanda Rowlands, Abdulsalam Abu-Libdeh, Asmahane Ladjouze, Rasha T Hamza, Salwa A Musa, Farida Jennane, Bouferoua Fadila, Delileche Hana, Djahlat Larbi, Noumi Mustapha, Haya Alkhayyat, Abdourahman Douksie, Ali Rabbani, Ali Al-Jumaili, Rasha Odeh, Hessa Alkandari, Hala Tfayli, Suleiman Abusrewil, Millad Ghawil, Aisha Al senani, Fawziya Alkhalaf, Abdelhadi Habeb, Noman Ahmad, Omer Elshareef, Mohamed Abdullah, Olivia Al-Hassan, Dima Karah, Mongia Hachicha, Mohammed Alshakka   +32 more
doaj   +2 more sources

Evolution and Comparison Effects of Fludrocortisone and Betamethasone on Glucose and Lipid Profile in Rats

Acta Medica Iranica, 2020
Hyperglycemia may associate with improper use of glucocorticoids, impaired insulin function, or both, and is associated with many complications such as hyperlipidemia and Hyperglycemia.
Hamid Reza Reza Jamshidi, Mohammad Naeem Malmir   +1 more
doaj   +2 more sources

Fludrocortisone Is Associated With a Higher Risk of All‐Cause Hospitalizations Compared With Midodrine in Patients With Orthostatic Hypotension

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundOrthostatic hypotension causes ≈80 000 hospitalizations per year in the United States. Treatments for orthostatic hypotension include fludrocortisone, a mineralocorticoid analog that promotes sodium reabsorption; and midodrine, an α‐1 ...
Carlos G. Grijalva, Italo Biaggioni, Marie R. Griffin, Cyndya A. Shibao   +3 more
doaj   +2 more sources

Evaluation of the role of hydrocortisone either alone or combined with fludrocortisone in the outcome of septic shock in adults

Ain Shams Journal of Anesthesiology, 2022
Background Management of sepsis is a time critical procedure; the consequences of improperly managed sepsis and septic shock can cause multiple organ dysfunction and death.
Heba A. Labib, Ali I. Hassan, Ayman M. Kamaly, Sherif S. Wahba, Mona A. Ammar   +4 more
doaj   +2 more sources

Effects of low-dose hydrocortisone and hydrocortisone plus fludrocortisone in adults with septic shock: a protocol for a systematic review and meta-analysis of individual participant data

BMJ Open, 2020
Introduction The benefits and risks of low-dose hydrocortisone in patients with septic shock have been investigated in numerous randomised controlled trials and trial-level meta-analyses. Yet, the routine use of this treatment remains controversial.
Yaseen Arabi, Sylvie Chevret, Laurent Billot, Anthony Gordon, Didier Keh, Romain Pirracchio, Balasubramanian Venkatesh, Djillali Annane, Andre Waschka, Jeremy Cohen, Simon Finfer, Naomi Hammond, John Myburgh, Anthony Delaney, Pierre Edouard Bollaert, Josef Briegel, Ling Liu, G Umberto, Liliana Mirea, L Charles, Nejla Tilouche, Surat Tongyoo, Ruiqiang Zheng   +22 more
doaj   +2 more sources

StAR Protein Deficiency in Clinical Practice: A Case Series From Saudi Arabia. [PDF]

Case Rep Endocrinol
Objectives Steroidogenic acute regulatory (StAR) protein deficiency is a rare autosomal recessive disorder that disrupts steroid hormone biosynthesis, resulting in congenital adrenal hyperplasia (CAH) and variations in sexual development. However, limited data is available in Saudi Arabia.
Alabduljabbar A, Farooq D, Abid S, Aljazaeri S, Alhuthil R, Alsagheir A.   +5 more
europepmc   +2 more sources

Genetic Insights and Lifelong Management of Aldosterone Synthase Deficiency: A Case of Hyperreninemic Hypoaldosteronism. [PDF]

Clin Case Rep
ABSTRACT Aldosterone synthase deficiency is a rare cause of neonatal salt‐wasting and failure to thrive. Routine newborn electrolyte screening after 5 days of life is vital for early detection and prevention of life‐threatening crises. Genetic confirmation enables targeted fludrocortisone therapy, ensuring favorable growth and developmental outcomes.
Ahmed MMH, Waris R, Batool S, Omarzai RG, Rehman A.   +4 more
europepmc   +2 more sources

Adrenal Insufficiency due to Disseminated <i>Cryptococcus</i> in an Immunocompetent Individual. [PDF]

Case Rep Endocrinol
Primary adrenal insufficiency due to infiltrative fungal infections, such as Cryptococcus neoformans, is rare, particularly in immunocompetent patients. We present a case of an immunocompetent 61‐year‐old man who presented with bilateral adrenal enlargement and adrenal insufficiency, with a 3‐month history of generalised fatigue, weight loss and ...
Knott JA, Apostoloski Z.
europepmc   +2 more sources