Blood PressureIntroduction Fludrocortisone and midodrine are frequently used to raise blood pressure (BP) in patients with vasovagal syncope (VVS)/low BP phenotype and orthostatic hypotension (OH), despite limited supporting evidence.
Kate Doyle +4 more
doaj +2 more sources
Association of mortality with fludrocortisone addition to hydrocortisone treatment among septic shock patients: a propensity score matching analysis [PDF]
Frontiers in Medicine, 2023 BackgroundSeveral clinical trials of corticosteroids have been carried out in the treatment of septic shock, however, the therapeutic effect of the most widely used hydrocortisone is still controversial, and no studies have directly compared ...
Xiaoxiao Cheng +4 more
doaj +2 more sources
Oral Fludrocortisone Test for Salt-Sensitive Screening in Hypertensive Patients: A Randomized Crossover Trial [PDF]
International Journal of Hypertension, 2018 Background. Salt sensitivity is associated with an increased cardiovascular risk, but the gold standard method (diet cycles) requires 24-h urine samples and has poor patient compliance. Objectives.
Andrea Pio-Abreu +4 more
doaj +2 more sources
Use of fludrocortisone for intradialytic hypotension
Kidney Research and Clinical Practice, 2018 Intradialytic hypotension during dialysis adversely affects a patient's prognosis and increases mortality. We report a case in which intradialytic hypotension that persisted after the administration of midodrine was relieved after the use of ...
Yuri Seo +5 more
doaj +3 more sources
Access to fludrocortisone and to hydrocortisone in children with congenital adrenal hyperplasia in the WHO Eastern Mediterranean Region: it takes a village… [PDF]
BMJ Global Health, 2021 Congenital adrenal hyperplasia (CAH), if untreated, carries high morbidity and mortality. A higher incidence of CAH is expected in countries where consanguinity is common, such as in the countries of the WHO Eastern Mediterranean Region (EMRO).
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Chronic urine acidification by fludrocortisone to treat infectious kidney stones [PDF]
Comptes Rendus. Chimie, 2021 Chronic urinary tract infections by urease-producing bacteria may increase urine pH and promote thereby the formation of recurrent kidney stones made of highly carbonated calcium phosphate apatite and struvite, a magnesium ammonium phosphate.
Lionet, Arnaud +4 more
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Performance of renin assays in selecting fludrocortisone dose in children with adrenal disorders [PDF]
Endocrine ConnectionsChildren with salt-wasting adrenal insufficiency are managed with glucocorticoid and mineralocorticoid replacement. Measurement of renin activity or concentration alongside blood electrolyte levels is used to monitor the adequacy of mineralocorticoid ...
Timothy J Morris +6 more
doaj +2 more sources
Cerebral Salt Wasting Syndrome following Head Injury in a Child Managed Successfully with Fludrocortisone [PDF]
Case Reports in Pediatrics, 2016 Cerebral salt wasting (CSW) syndrome is an important cause of hyponatremia in head injuries apart from syndrome of inappropriate antidiuretic hormone (SIADH). Proper diagnosis and differentiation between these two entities are necessary for management as
Nagendra Chaudhary +3 more
doaj +2 more sources
StAR Protein Deficiency in Clinical Practice: A Case Series From Saudi Arabia. [PDF]
Case Rep EndocrinolObjectives Steroidogenic acute regulatory (StAR) protein deficiency is a rare autosomal recessive disorder that disrupts steroid hormone biosynthesis, resulting in congenital adrenal hyperplasia (CAH) and variations in sexual development. However, limited data is available in Saudi Arabia.
Alabduljabbar A +5 more
europepmc +2 more sources
Genetic Insights and Lifelong Management of Aldosterone Synthase Deficiency: A Case of Hyperreninemic Hypoaldosteronism. [PDF]
Clin Case RepABSTRACT Aldosterone synthase deficiency is a rare cause of neonatal salt‐wasting and failure to thrive. Routine newborn electrolyte screening after 5 days of life is vital for early detection and prevention of life‐threatening crises. Genetic confirmation enables targeted fludrocortisone therapy, ensuring favorable growth and developmental outcomes.
Ahmed MMH +4 more
europepmc +2 more sources