Results 81 to 90 of about 10,175 (227)
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin +8 more
wiley +1 more source
High‐dose steroid pulse therapy markedly reduces total sleep time, REM, and NREM sleep, as objectively demonstrated for the first time using a portable EEG‐based device. ABSTRACT Background Sleep disturbance is a common side effect of high‐dose steroid pulse therapy (SPT).
Hiroki Endo +12 more
wiley +1 more source
Background Autonomic dysfunction, including orthostatic hypotension and postural tachycardia syndrome, has emerged as a COVID-19 complication.
Daisuke Miyamori, Masanori Ito
doaj +1 more source
Pseudohypoaldosteronism type 1 due to novel variants of SCNN1B gene. [PDF]
UnlabelledAutosomal recessive pseudohypoaldosteronism type 1 (PHA1) is a rare disorder characterized by sodium wasting, failure to thrive, hyperkalemia, hypovolemia and metabolic acidosis.
Abraham, Smita B +9 more
core +2 more sources
Renal tubular acidosis: A ‘basic’ disorder
Equine Veterinary Education, EarlyView.
H. J. Mason, L. G. Arroyo
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Nuclear hormone receptors
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +20 more
wiley +1 more source
A novel detrimental homozygous mutation in the WFS1 gene in two sisters from nonconsanguineous parents with untreated diabetes insipidus [PDF]
Given the limited lifespan and with the recent progress in experimental treatments for WS, timely diagnosis and multidisciplinary treatment for DI/DM, hydronephrosis, and visual/psychiatric status-maintaining quality of life-are of crucial ...
Delides, Alexandros +11 more
core +2 more sources
Effect of stress doses of hydrocortisone on S-100B vs. interleukin-8 and polymorphonuclear elastase levels in human septic shock [PDF]
Stress doses of hydrocortisone a re known to have immunomodulatory effects in patients with hyperdynamic septic shock. The prognosis correlates with the presence and severity of septic encephalopathy. However, neurological evaluation is influenced by the
Anderson +46 more
core +2 more sources
Infants With Congenital Adrenal Hyperplasia Are at Risk for Hypercalcemia, Hypercalciuria, and Nephrocalcinosis [PDF]
In a retrospective study, most young children with CAH had at least one episode of hypercalcemia, whereas a smaller percentage was found to have hypercalciuria and/or ...
Imel, Erik A. +4 more
core +1 more source

