Results 81 to 90 of about 10,229 (223)

Renal tubular acidosis: A ‘basic’ disorder

Equine Veterinary Education, EarlyView.
H. J. Mason, L. G. Arroyo
wiley   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, Volume 1, Issue 3, Page 322-358, December 2025.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

Pseudohypoaldosteronism type 1 due to novel variants of SCNN1B gene. [PDF]

, 2016
UnlabelledAutosomal recessive pseudohypoaldosteronism type 1 (PHA1) is a rare disorder characterized by sodium wasting, failure to thrive, hyperkalemia, hypovolemia and metabolic acidosis.
Abraham, Smita B, Belyavskaya, Elena, Faucz, Fabio R, Lodish, Maya B, Lyssikatos, Charalampos, Nobel, Yael R, Raygada, Margarita, Rivero, Jaydira Del, Stratakis, Constantine A, Zilbermint, Mihail   +9 more
core   +2 more sources

Sleep Architecture Alterations Following High‐Dose Steroid Pulse Therapy: A Pilot Study Using a Portable Electroencephalogram‐Based Device

Neuropsychopharmacology Reports, Volume 45, Issue 4, December 2025.
High‐dose steroid pulse therapy markedly reduces total sleep time, REM, and NREM sleep, as objectively demonstrated for the first time using a portable EEG‐based device. ABSTRACT Background Sleep disturbance is a common side effect of high‐dose steroid pulse therapy (SPT).
Hiroki Endo, Yuki Shigetsura, Misaki Chahara, Keisuke Kido, Etsuro Nakanishi, Sakiho Ueda, Kimitoshi Kimura, Akira Kuzuya, Hirotsugu Kawashima, Riki Matsumoto, Masahiro Tsuda, Shunsaku Nakagawa, Tomohiro Terada   +12 more
wiley   +1 more source

A novel detrimental homozygous mutation in the WFS1 gene in two sisters from nonconsanguineous parents with untreated diabetes insipidus [PDF]

, 2019
Given the limited lifespan and with the recent progress in experimental treatments for WS, timely diagnosis and multidisciplinary treatment for DI/DM, hydronephrosis, and visual/psychiatric status-maintaining quality of life-are of crucial ...
Delides, Alexandros, Dinopoulos, Argyrios, Kleanthous, Kleanthis, Manolakos, Emmanouil, Mastorakos, Georgios, Nikolopoulos, Thomas, Papadimitriou, Anastasios, Papadimitriou, Dimitrios T, Tiulpakov, Anatoly, Urano, Fumihiko, Voros, Gerasimos, Zoupanos, George   +11 more
core   +2 more sources

The Concise Guide to PHARMACOLOGY 2025/26: Nuclear hormone receptors

British Journal of Pharmacology, Volume 182, Issue S1, Page S242-S258, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, John A. Cidlowski, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Laurel Coons, Peter J. Fuller, Kenneth S. Korach, Donald P. McDonell, Robert Oakley, Sarah Radi, Rachid Safi, Frances Sladek, Morag J. Young   +20 more
wiley   +1 more source

Fludrocortisone improves endometrial receptivity by regulating expression of ENaC, SGK1, HAND2, miR-200a, miR-145, miR-451, mTOR, and 4E-BP1 during the implantation window in mice [PDF]

Journal of Research in Applied and Basic Medical Sciences
Background & Aims: This study investigated the effect of fludrocortisone treatment on the expression of genes and proteins involved in the implantation process in mice.
Mohammad Bakhtiar Hesam Shariati, Behrooz Niknafs, Naser Shokrzadeh   +2 more
doaj  

Comparative long-term evaluation of tacrolimus and cyclosporine in pediatric liver transplantation [PDF]

, 2000
Background. In this report, we compare the long-term outcome of pediatric liver transplantation (LTx) patients maintained with tacrolimus-based and with cyclosporine (CsA)-based immunosuppressive therapy.
Fung, J, Green, M, Gronsky, C, Jain, A, Kashyap, R, Mazariegos, G, Reyes, J, Starzl, TE   +7 more
core   +1 more source

Catch-up Growth and Discontinuation of Fludrocortisone Treatment in Aldosterone Synthase Deficiency [PDF]

, 2021
Büşra Gürpınar Tosun, Yasemin Kendir Demirkol, tuba seven menevse, Sare Betül Kaygusuz, Mehmet Nuri Özbek, Selda Ayça Altıncık, Jamala Mammadova, Atilla Çayır, Esra Döğer, Elvan Bayramoğlu, Özlem Nalbantoğlu, Gül Yeşiltepe Mutlu, Agharza Aghayev, Serap Turan, Abdullah Bereket, Tülay Güran   +15 more
openalex   +1 more source

Exenatide Once Weekly in the Treatment of Patients with Multiple System Atrophy

Annals of Neurology, Volume 98, Issue 5, Page 991-1003, November 2025.
Objective Exenatide, a glucagon‐like peptide‐1 (GLP‐1) receptor agonist, has neuroprotective effects in preclinical models of multiple system atrophy (MSA). We investigated these effects in a proof‐of‐concept clinical trial. Methods In this single‐center, randomized, open label trial, participants with MSA were randomly assigned (1:1) to receive ...
Nirosen Vijiaratnam, Christine Girges, Martin Wiegand, Claudia Ismail, Alexandra Lameirinhas, Alison Yarnall, Cameron Kirk, Silvia Del‐Din, Lynn Rochester, Christopher Kobylecki, Gareth Ambler, Simon Skene, Henry Houlden, Viorica Chelban, Amanda Heslegrave, Wendy Phillips, Alan Whone, Niall Quinn, Christian Lambert, Charlotte Dore, Huw R. Morris, Mathew H. Horrocks, Ji Eun Lee, Judi O'Shaughnessy, Yazhou Li, Nigel H. Greig, Sonia Gandhi, Vincenzo Libri, Dilan Athauda, Tom Foltynie   +29 more
wiley   +1 more source