Results 71 to 80 of about 137,504 (309)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Behavioural fluency for young children with autism

open access: yes, 2002
Fluency is functionally defined by: skill retention after a period without practice; skill endurance over longer intervals than encountered during practice; skill stability in the face of distraction; a performance that can be effortlessly applied to new
Bonser, David J.
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

THE EFFECTS OF SYMMETRICAL AND ASYMMETRICAL SCAFFOLDING ON SPEAKING COMPLEXITY, ACCURACY, AND FLUENCYTHE EFFECTS OF SYMMETRICAL AND ASYMMETRICAL SCAFFOLDING ON SPEAKING COMPLEXITY, ACCURACY, AND FLUENCY

open access: yesIndonesian EFL Journal, 2018
This experimental study was set ought to explore the efficacy of symmetrical and asymmetrical scaffolding in boosting speaking complexity, accuracy, and fluency among 38 upper-intermediate EFL learners.
Parviz Ghasedi   +3 more
doaj   +1 more source

Quantitative and qualitative impairments in semantic fluency, but not phonetic fluency, as a potential risk factor for Alzheimer's disease

open access: yes, 2004
Qualitative aspects of verbal fluency may be more useful in discerning the precise cause of any quantitative deficits in phonetic or category fluency, especially in the case of mild cognitive impairment (MCI), a possible intermediate stage between normal
O'Dowd, B.   +4 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Is speaking fluency strand necessary for the college students to develop in the EFL class? [PDF]

open access: yes, 2014
This article aims to explore how the EFL teachers and students treat the development of speaking fluency in the EFL class in terms of the teachers' willingness of promoting speaking fluency for their students and the students' demand and preference of ...
Yang, Yingjie I. J.
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

EU education of fluency specialists : an innovative program

open access: yes, 2009
C
Eggers, KurtGE378020037463570000-0003-4221-2063219beb80-f314-11eb-8156-c87de931f959   +2 more
core  

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