Results 51 to 60 of about 389,563 (238)

Hydro-micromechanical modeling of wave propagation in saturated granular media [PDF]

open access: yes, 2018
Biot's theory predicts the wave velocities of a saturated poroelastic granular medium from the elastic properties, density and geometry of its dry solid matrix and the pore fluid, neglecting the interaction between constituent particles and local flow ...
Cheng, Hongyang   +4 more
core   +4 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Development of 6-way CFD-DEM-FEM momentum coupling interface using partitioned coupling approach

open access: yesResults in Engineering
Fluid-particle-structure interactions (FPSI) govern a wide range of natural and engineering phenomena, from landslides to erosion in abrasive water jet cutting nozzles. Despite the importance of studying FPSI, existing numerical frameworks often simplify
Prasad Adhav   +2 more
doaj   +1 more source

Fluid–structure interaction study of three-dimensional vehicle model under crosswind

open access: yesAdvances in Mechanical Engineering, 2015
It is very important to study fluid–structure interaction of vehicles which move in strong crosswind environment. For solving a fluid–structure interaction problem, the effect of the deformation and vibration of the elastic body on the flow field should ...
Hui Zhu, Yang Zhigang
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Research Method of Wellbore Stability of Coal Formation in the Daniudi Gas Field

open access: yesShiyou jixie, 2015
Most studies on the coalbed wellbore stability are based on continuum mechanics,few research has involved fluid-structure coupling.The coal mechanical properties have been studied through the uniaxial and 3-axis compressive strength test of coal samples ...
Cheng Fushan   +5 more
doaj  

Fluid Structure Interaction Using Modal Superposition and Lagrangian CFD

open access: yesJournal of Marine Science and Engineering
This study investigates the impact of fluid loads on the elastic deformation and dynamic response of linear structures. A weakly coupled modal solver is presented, which involves the solution of a dynamic equation of motion with external loads.
Manigandan Paneer   +5 more
doaj   +1 more source

Coupling analysis of contra-rotating fan interstage pressure pulsation and blade vibration based on wavelet reconstruction.

open access: yesPLoS ONE, 2021
In recent years, the flow characteristics research of the interstage region in counter-rotating axial fans in terms of fluid dynamics has attracted much attention.
Xinzhe Zhang   +4 more
doaj   +1 more source

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