Results 111 to 120 of about 4,591,879 (304)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
STUDY OF FLUID OUTFLOW THROUGH THROTTLE CHANNELS WITH CAVITATION INITIATION
Вестник Донского государственного технического университета, 2018 The experimental study results of several hydrodynamic parameters of fluid discharge through the throttle channels of cylindrical or flat forms are offered.
Valery S. Kuznetsov
doaj
Metastability and nucleation in the dilute fluid phase of a simple model of globular proteins
, 1999 The dilute fluid phase of model globular proteins is studied. The model possesses a fluid-fluid transition buried within the fluid-crystal coexistence region, as do some globular proteins.
Sear, Richard P.
core
Curved film cooling admission tube [PDF]
, 1980 Effective film cooling to protect a wall surface from a hot fluid which impinges on or flows along the surface is provided. A film of cooling fluid having increased area is provided by changing the direction of a stream of cooling fluid through an angle ...
Graham, R. W., Papell, S. S.
core +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Fluid Dynamics Without Fluids [PDF]
, 2012 This chapter will discuss some interesting real applications where Fluid Dynamics equations found fruitful applications without dealing with "strictly speaking" fluids. In particular, thanks to the large set of analyses performed over different kinds of fluids in different operating and boundary conditions, a wide range of Computational Fluid Dynamics ...
openaire +2 more sources
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
, 2008 Abstract This chapter presents general properties of perfect fluids. When appropriate definitions are given, some of these properties generalize well-known properties of non-relativistic perfect fluids. However, the equivalence of mass and energy in Relativity introduces some fundamental differences.
openaire +1 more source
NASA Lewis Research Center low-gravity fluid management technology program [PDF]
, 1985 A history of the Lewis Research Center in space fluid management technology program is presented. Current programs which include numerical modeling of fluid systems, heat exchanger/radiator concept studies, and the design of the Cryogenic Fluid ...
Aydelott, J. C. +2 more
core +1 more source