Results 61 to 70 of about 1,238,717 (284)

Modelling of anthropogenic pollutant diffusion in the atmosphere and applications to civil protection monitoring

open access: yes, 2008
A basic feature of fluid mechanics concerns the frictionless phase-space dynamics of particles in an incompressible fluid. The issue, besides its theoretical interest in turbulence theory, is important in many applications, such as the pollutant dynamics
Marco Tessarotto   +2 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Quantifying Equilibrium Climate Sensitivity to Atmospheric Chemistry and Composition Representations in GFDL‐CM4.0 and GFDL‐ESM4.1

open access: yesGeophysical Research Letters
Equilibrium climate sensitivity (ECS) quantifies surface warming in response to doubled pre‐industrial CO2 (2xCO2). Uncertainty in estimates arises from diverse model representations and climate‐chemistry feedbacks.
L. T. Sentman   +6 more
doaj   +1 more source

On the Flight Control of Flapping Wing Micro Air Vehicles with Model-Based Reinforcement Learning

open access: yesProceedings
Hummingbirds and insects can hover in disturbed conditions, escape from predators with a very fast response, fly for miles without landing, etc [...]
Romain Poletti   +2 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Large eddy simulations of methane oxidation at ultra-wet conditions in a model gas turbine combustor applying detailed chemistry

open access: yesJournal of Fluid Science and Technology, 2014
The addition of steam to the combustion process is a promising avenue, in order to reduce harmful emissions and simultaneously increase the efficiency. In contrast to traditional flames where the heat release exhibits a thin flame front, operating under ...
Oliver KRÜGER   +3 more
doaj   +1 more source

Dissipative hydrodynamics in 2+1 dimension

open access: yes, 2006
In 2+1 dimension, we have simulated the hydrodynamic evolution of QGP fluid with dissipation due to shear viscosity. Comparison of evolution of ideal and viscous fluid, both initialised under the same conditions e.g.
A. K. Chaudhuri   +4 more
core   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Steady linked vortices with chaotic streamlines

open access: yes, 2010
This paper contains background information for a fluid dynamics video submitted to the Gallery of Fluid Motion to be held along with the 63rd Annual Meeting of the American Physical Society's Division of Fluid Dynamics.Comment: 2 videos (high and low ...
Angélica Romero Arteaga   +8 more
core   +1 more source

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