Results 121 to 130 of about 4,332,918 (396)

Alteration, mineralization, geochemistry and fluid inclusion investigations in Joftrud prospect area, southwest of Birjand

open access: yesJournal of Economic Geology
The Joftrud prospect area is located in the central Lut Block and 60 Km of Birjand city. The area comprises outcrops of pyroclastic (andesitic tuff), volcanic (hornblende andesite, pyroxene andesite, basaltic andesite), intrusive (diorite porphyry ...
Omid Shareipour   +2 more
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Pulsed Injections of Metal‐Rich Magmatic Fluids: Key Drivers of Mineralization in a Back‐Arc Basin Hydrothermal System

open access: yesGeochemistry, Geophysics, Geosystems
Submarine magmatic–hydrothermal systems, where magmatic volatiles and fluids possibly serve as major sources of mineralization elements, have been extensively documented in numerous felsic‐hosted hydrothermal fields.
Xia Zhang   +5 more
doaj   +1 more source

Thermo-acoustic wave propagation and reflection near the liquid-gas critical point

open access: yes, 2009
We study the thermo-acoustic wave propagation and reflection near the liquid-gas critical point. Specifically, we perform a numerical investigation of the acoustic responses in a near-critical fluid to thermal perturbations based on the same setup of a ...
A. Onuki   +5 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Hydrocarbon Fluid Inclusion Fluorescence: A Review

open access: yes, 2009
Geological fluid inclusions are small voids that can contain a variety of liquids which are often found in natural minerals and rocks. Typically they are less than 10 micrometres in size that host fossil fluids which existed when the minerals grew or healed after fracture.
Blamey, Nigel J. F., Ryder, Alan G.
openaire   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Home - About - Disclaimer - Privacy