Results 111 to 120 of about 109,213 (331)

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Fluctuation-induced forces between inclusions in a fluid membrane under tension

, 2011
We discuss the fluctuation-induced force, a finite-temperature analog of the Casimir force, between two inclusions embedded in a fluid membrane under tension.
B. Alberts, H. Hellmann, Hsiang-Ku Lin, Leonid P. Pryadko, Roya Zandi, Umar Mohideen, W. Helfrich   +6 more
core   +1 more source

Magmatic and Metamorphic Fluids in Pegmatite Development: Evidence from Borujerd Complex, Iran [PDF]

Journal of Sciences, Islamic Republic of Iran, 2005
The Borujerd complex of western Iran is composed of intrusions and their surrounding contact aureole, with, pegmatites and quartz veins. Pegmatites differ in mineralogy, origin and age, and two groups can be distinguished. The Older Pegmatites (about 120
doaj  

Phase transitions in natural C-O-H-N-S fluid inclusions - implications for gas mixtures and the behavior of solid H₂S at low temperatures. [PDF]

Nat Commun, 2021
Sośnicka M, Lüders V.
europepmc   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Characteristics of Ore-forming Fluid and Mineralization of Jinqingding Gold Deposit in Mouru Metallogenic Belt, Jiaodong

Kuangchan zonghe liyong
The Mouru Gold Metallogenic Belt is one of the three major one in the Jiaodong Gold Metallogenic Zone. The Jinqingding Gold Deposit is located in the southern part of the metallogenic belt and is a large quartz vein-type gold one. The research on its ore-
Qian SONG, Xin HUANG, Yongjun WANG, Yubao SHAO, Changyong LU, Silong LI   +5 more
doaj   +1 more source

Curvature correction to the mobility of fluid membrane inclusions [PDF]

The European Physical Journal E, 2016
Using rigorous low-Reynolds-number hydrodynamic theory on curved surfaces, we provide, via a Stokeslet-type approach, a general and concise expression for the leading-order curvature correction to the canonical, planar, Saffman-Delbrück value of the diffusion constant for a small inclusion embedded in an arbitrarily (albeit weakly) curved fluid ...
openaire   +5 more sources

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Characteristics and carbon stable isotopes of fluids in the Southern Kerala granulites and their bearing on the source of CO2 [PDF]

Carbon dioxide-rich inclusions commonly occur in the banded charnockites and khondalites of southern Kerala as well as in the incipient charnockites formed by desiccation of gneisses along oriented zones.
Harris, N. B. W., Jackson, D. H., Mattey, D. P., Santosh, M.   +3 more
core   +1 more source

Sources of the fluids for metasomatic magnesite of Ismakaevo deposit in the South Ural province (thermokryometry of fluid inclusions)

Литосфера, 2015
Bittern brine nature of fluid inclusions in magnesite of Ismakaevo deposits are confirmed not only by data of Cl-Br ion systematics, but also by methods of microthermometry.
M. T. Krupenin, A. A. Garaeva
doaj   +2 more sources