Results 41 to 50 of about 256,414 (305)

Assessment of RANS turbulence models and Zwart cavitation model empirical coefficients for the simulation of unsteady cloud cavitation [PDF]

, 2019
The numerical simulation of unsteady cavitation flows is sensitive to the selected models and associated parameters. Consequently, three Reynolds Average Navier-Stokes (RANS) turbulence models and the Zwart cavitation model were selected to assess their ...
Escaler Puigoriol, Francesc Xavier, Geng, Linlin   +1 more
core   +2 more sources

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Boundary layer tripping on a transonic compressor profile

Archives of Mechanics
The numerical and experimental investigation of boundary layer tripping using steps on the suction side of a transonic compressor rotor has been presented in this paper.
A. Joseph, M. Piotrowicz, P. Flaszynski, P. Doerffer, P. Kaczynski   +4 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Atmospheric pressure microwave (915 MHz) plasma for hydrogen production from steam reforming of ethanol

Scientific Reports
This work presents experimental results on the energy efficiency in hydrogen production using atmospheric microwave plasma (915 MHz) through steam reforming of ethanol. Ethanol was chosen as a liquid hydrogen carrier due to its high hydrogen atom content,
Robert Miotk, Bartosz Hrycak, Dariusz Czylkowski, Mariusz Jasiński, Mirosław Dors, Jerzy Mizeraczyk   +5 more
doaj   +1 more source

Damage assessment in wind turbine technology

E3S Web of Conferences, 2017
The economic efficiency of wind turbines WT is strictly dependent on their availability and reliability. This problem is most important in the case of offshore wind turbines OWT.
Ostachowicz Wiesław, Malinowski Paweł H., Soman Rohan, Wandowski Tomasz   +3 more
doaj   +1 more source

A Bramble-Pasciak-like method with applications in optimization [PDF]

, 2008
Saddle-point systems arise in many applications areas, in fact in any situation where an extremum principle arises with constraints. The Stokes problem describing slow viscous flow of an incompressible fluid is a classic example coming from partial ...
Dollar, H. Sue, Gould, Nicholas I. M., Stoll, Martin, Wathen, A. J.   +3 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Fluid Mechanics and Machinery

"Fluid Mechanics and Machinery" is a comprehensive guide designed for students, engineers, and professionals in mechanical and civil engineering. The book covers fundamental and advanced concepts in fluid mechanics, including fluid properties, flow dynamics, and machinery applications.
Dr. G. Karthikeyan, Mr. Kiran CH, Dr. S.Vijayan, Mr. G. Kasirajan   +3 more
openaire   +3 more sources

Role of ethanol to water ratio in hydrogen production by ethanol steam reforming in atmospheric pressure 915 MHz microwave plasma

Scientific Reports
As interest in the hydrogen economy grows, the demand for efficient, cost-effective, and sustainable hydrogen production methods increases. In response, this work focuses on developing a small-scale hydrogen production method based on ethanol steam ...
Robert Miotk, Bartosz Hrycak, Dariusz Czylkowski, Jerzy Mizeraczyk, Mirosław Dors, Mariusz Jasiński   +5 more
doaj   +1 more source