Results 91 to 100 of about 4,134,004 (303)

Fluid, electrolyte, and acid-base disorders in small animal practice /

, 2006
This comprehensive resource brings together cutting edge information about fluid, electrolyte, and acid-base physiology and fluid therapy as they apply to small animal practice. It also offers complete coverage of relevant physiology and pathophysiology,
DiBartola, Stephen P., DiBartola, Stephen P.Fluid therapy in small animal practice.   +1 more
core  

Fluidoterapia perioperatoria en niños [PDF]

Revista Chilena de Anestesia, 2022
Marcos Rattalino, Mario Concha Pinto
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Goal-directed haemodynamic therapy during elective total hip arthroplasty under regional anaesthesia. [PDF]

, 2011
INTRODUCTION: Total hip replacement is one of the most commonly performed major orthopaedic operations. Goal-directed therapy (GDT) using haemodynamic monitoring has previously demonstrated outcome benefits in high-risk surgical patients under general ...
Michele Divella, Della Rocca, G, Nicola Langiano, Nicola Fasano, COSTA, Maria Gabriella, DELLA ROCCA, Giorgio, Fasano, N, Maria G Costa, Cecconi, M, Maurizio Cecconi, Divella, M, RHODES A, Rhodes, A, DIVELLA M, Costa, MG, Giorgio Rocca, FASANO N, CECCONI M, LANGIANO N, Langiano, N, Andrew Rhodes   +20 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Treatment of experimental hyperchloremic metabolic acidosis in horses with enteral electrolyte solution containing sodium acetate

Frontiers in Veterinary Science
IntroductionIn adult horses, the development and evaluation of enteral electrolyte solutions containing sodium acetate for correcting hyperchloremic metabolic acidosis are still lacking, although these electrolyte and acid–base imbalances are commonly ...
Lorena Chaves Monteiro, Caio Monteiro Costa, Pedro Ancelmo Nunes Ermita, Silvio José Printes Gomes Júnior, Felipe Sperandio Mattos, Fernanda Campos Mansur, Mayara Oliveira dos Santos, Samuel Rodrigues Alves, Erica Garcia Mafort, Cíntia Fernandes Fidélis, Marcel Ferreira Bastos Avanza, Raffaella Bertoni Cavalvanti Teixeira, Rinaldo Batista Viana, José Dantas Ribeiro Filho   +13 more
doaj   +1 more source

Hidratación oral con una solución a base de harina de plátano precocida con electrolitos estandarizados.

Biomédica: revista del Instituto Nacional de Salud, 2005
Objetivo. El objetivo del presente trabajo fue determinar si una solución de hidratación oral a base de harina de plátano precocida con electrolitos, además de ser efectiva para tratar la deshidratación, tiene propiedades antidiarreicas.
Carlos Bernal, Gloria Margarita Alcaraz, Jorge Eliécer Botero   +2 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Neuroimaging Applications for the Delivery and Monitoring of Gene Therapy for Central Nervous System Diseases

Neurological disease due to single gene defects represents a targetable entity for adeno-associated virus (AAV) mediated gene therapy. The delivery of AAV-mediated gene therapy to the brain is challenging, owing to the presence of the blood-brain barrier.
Vardar, Zeynep, Gray-Edwards, Heather L, Daci, Rrita, Flotte, Terence R, Shazeeb, Mohammed Salman, Cataltepe, Oguz I, Vachha, Behroze   +6 more
core   +1 more source