Results 101 to 110 of about 656,113 (361)

Treatment of experimental hyperchloremic metabolic acidosis in horses with enteral electrolyte solution containing sodium acetate

open access: yesFrontiers in Veterinary Science
IntroductionIn adult horses, the development and evaluation of enteral electrolyte solutions containing sodium acetate for correcting hyperchloremic metabolic acidosis are still lacking, although these electrolyte and acid–base imbalances are commonly ...
Lorena Chaves Monteiro   +13 more
doaj   +1 more source

Hidratación oral con una solución a base de harina de plátano precocida con electrolitos estandarizados.

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2005
Objetivo. El objetivo del presente trabajo fue determinar si una solución de hidratación oral a base de harina de plátano precocida con electrolitos, además de ser efectiva para tratar la deshidratación, tiene propiedades antidiarreicas.
Carlos Bernal   +2 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Term amniotic fluid [Elektronisk resurs] : An unexploited reserve of mesenchymal stromal cells for reprogramming and potential cell therapy applications

open access: yes, 2017
Background: Mesenchymal stromal cells (MSCs) are currently being evaluated in numerous pre-clinical and clinical cell-based therapy studies. Furthermore, there is an increasing interest in exploring alternative uses of these cells in disease modelling ...
Herbst, Andreas,   +9 more
core   +1 more source

Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin [PDF]

open access: yes, 2005
Pathological processes involved in the initiation of rheumatoid synovitis remain unclear. We undertook the present study to identify immune and stromal processes that are present soon after the clinical onset of rheumatoid arthritis ( RA) by assessing a ...
Lee, CY   +28 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Understanding the principles and aims of intravenous fluid therapy

open access: yes, 2020
A balance between the volume of fluid taken in by the human body, and the volume of fluid excreted, is essential for life. Body fluid balance, which is maintained via various homeostatic mechanisms, can be disrupted by injury or disease. Prompt action is
Guest, Mags
core   +1 more source

Investigating the effectiveness of an intraoperative decision support guided fluid therapy intervention on postoperative outcome of high-risk patients undergoing high-risk abdominal surgery: protocol for an international multicentre stepped-wedge cluster-randomised implementation trial

open access: yesBJA Open
Background: Inappropriate fluid administration can impact patient outcome. Intraoperative advanced haemodynamic monitoring coupled with a treatment protocol based on stroke volume optimisation can help determine the appropriate timing for fluid boluses ...
Sean Coeckelenbergh   +26 more
doaj   +1 more source

Hidratação com bicarbonato de sódio não previne a nefropatia de contraste: ensaio clínico multicêntrico Hydration with sodium bicarbonate does not prevent contrast nephropathy: a multicenter clinical trial

open access: yesArquivos Brasileiros de Cardiologia, 2012
FUNDAMENTO: A exposição ao meio de contraste radiográfico pode causar comprometimento agudo da função renal. Há evidências limitadas e conflitantes de que a hidratação com bicarbonato de sódio previne a Nefropatia Induzida por Contraste (NIC) em ...
Vitor O. Gomes   +8 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

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