Results 131 to 140 of about 594,017 (304)

Muscle microRNAs in the cerebrospinal fluid predict clinical response to nusinersen therapy in type II and type III spinal muscular atrophy patients

, 2022
Iddo Magen, Sharon Aharoni, Nancy‐Sarah Yacovzada, Itay Tokatly Latzer, Christiano R. R. Alves, Liora Sagi, Aviva Fattal‐Valevski, Kathryn J. Swoboda, Jacob Katz, Elchanan Bruckheimer, Yoram Nevo, Eran Hornstein   +11 more
openalex   +2 more sources

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

FLUID RESUSCITATION VOLUME FOR SEPTIC SHOCK PATIENTS WAS NOT DECREASED FOR ECHOCARDIOGRAM-DETERMINED LEFT VENTRICULAR (LV) SYSTOLIC DYSFUNCTION PATIENTS WHEN MANAGED WITH EARLY GOAL-DIRECTED THERAPY (EGDT) [PDF]

, 2007
Robert Updaw, Leah Passmore, Donna Mitten-Long, Cathy A. Pierce, Amelia Ross, Gretchen Wells, Peter E. Morris   +6 more
openalex   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

Antibiotic therapy in patients with amniotic fluid sludge and risk of preterm birth: a meta-analysis [PDF]

, 2023
Ioakeim Sapantzoglou, Vasilios Pergialiotis, Ioannis Prokopakis, Athanasios Douligeris, Sofoklis Stavros, Periklis Panagopoulos, Marianna Theodora, Panagiotis Antsaklis, G. Daskalakis   +8 more
openalex   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Fluid Therapy in Acute Pancreatitis-Current Knowledge and Future Perspectives. [PDF]

Pharmaceuticals (Basel)
Caban M, Zatorski H, Małecka-Wojciesko E.   +2 more
europepmc   +1 more source

Epidemiology of secondary fluid bolus therapy for infection-associated hypotension

, 2016
Miklós Lipcsey, I. Subiakto, Jonathan Chiong, Melissa Kaufman, Antoine Schneider, Rinaldo Bellomo   +5 more
openalex   +1 more source

Goal directed fluid therapy reduces major complications in elective surgery for abdominal aortic aneurysm: liberal versus restrictive strategies [PDF]

, 2016
Dina Y. Kassim, Ibrahim M. Esmat
openalex   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source