Results 251 to 260 of about 1,007,541 (342)

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

The efficacy and safety of isotonic and hypotonic fluids in intravenous maintenance fluid therapy in term newborns: national multicenter observational "neofluid" study. [PDF]

Front Nutr
Ozkan H, Duman N, Tuzun F, Narter F, Akyildiz C, Altuncu E, Satar M, Ozdemir M, Kurt A, Tugcu AU, Konak M, Uygun SS, Yilmaz Semerci S, Dikmen RT, Baysal B, Zeybek CK, Kostekci YE, Sahin S, Tutal M, Anik A, Buyuktiryaki M, Karagol BS, Tunç G, Colak D, Cetin H, Orman A, Olukman O, Deveci MF, Sarici D, Cakir SC, Keskinoglu P.   +30 more
europepmc   +1 more source

Fluid retention after initiation of thiazolidinedione therapy in diabetic patients with established chronic heart failure

, 2003
W.H. Wilson Tang, Gary S. Francis, Byron J. Hoogwerf, James B. Young   +3 more
openalex   +1 more source

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

Advanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo, Sara Menegazzo, Marcella Pantile, Silvia Bresolin, Carlo Zanon, Alessandro Davini, Massimiliano Mazzone, Alessandra Biffi, Sanja Aveic   +8 more
wiley   +1 more source

Investigating the effectiveness of an intraoperative decision support guided fluid therapy intervention on postoperative outcome of high-risk patients undergoing high-risk abdominal surgery: protocol for an international multicentre stepped-wedge cluster-randomised implementation trial. [PDF]

BJA Open
Coeckelenbergh S, Delaporte A, Rousseleau D, De Montblanc J, Roullet S, Ramadan J, Cholley B, Sitbon A, Weiss E, Kassab MC, Diop S, Manzi E, Pustetto M, Porta Bonette G, Guinot PG, Guerci P, Vanhonacker D, Carrier FM, Alexander B, Rinehart J, Boldt D, Grogan T, Cannesson M, Duranteau J, Grimaldi L, Pereira B, Joosten A.   +26 more
europepmc   +1 more source

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

Fluid therapy and pulmonary complications in abdominal surgeries: randomized controlled trial. [PDF]

Braz J Anesthesiol
Castro GIP, Castro RSAP, Lima RME, Santos BND, Navarro E Lima LH.   +4 more
europepmc   +1 more source

Modelling Atherosclerotic Plaque Cap Mechanics: Microcalcifications Reduce Mechanical Properties in Mesenchymal Stromal Cell‐Based Model

Advanced Biology, EarlyView.
This study develops a tissue‐engineered model of the atherosclerotic cap using human mesenchymal stromal cells (MSCs). After 2 weeks of culture to produce a collagenous matrix, a mineralizing medium induces microcalcifications over 4 weeks. These constructs, imaged with second harmonic generation microscopy, lead to reduced ultimate stress at rupture ...
Imke L. Jansen, Deniz Şahin, Frank J.H. Gijsen, Eric Farrell, Kim van der Heiden   +4 more
wiley   +1 more source

Effects of fluid therapy with ringer's vs. ringer lactate solution on acid-base balance and serum electrolytes in patients undergoing coronary artery bypass graft surgery. [PDF]

J Cardiovasc Thorac Res
Hadipourzadeh F, Azarfarin R, Ziyaeifard M, Jamalian J, Ghadimi M, Chaibakhsh Y.   +5 more
europepmc   +1 more source

L'infusione di liquidi nei pazienti in extraospedaliero [PDF]

, 2011
Finelli, Andrea
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