Results 31 to 40 of about 3,823 (239)

Liquid dosage forms with antibacterial activity

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015
The development and implementation of effective liquid medicines with antiseptic action on the basis of new substances and their complex combinations into medical practice is an important task of modern pharmaceutical and medical science.
O. I. Mykhalyk
doaj   +1 more source

Bioactive fluorenes. Part III: 2,7-dichloro-9H-fluorene-based thiazolidinone and azetidinone analogues as anticancer and antimicrobial against multidrug resistant strains agents

open access: yesBMC Chemistry, 2020
Background Thiazoles, thiazolidinones and azetidinones are highly ranked amongst natural and synthetic heterocyclic derivatives due to their great pharmaceutical potential.
Essam M. Hussein   +9 more
doaj   +1 more source

Transformation of Substituted Fluorenes and Fluorene Analogs by Pseudomonas sp. Strain F274 [PDF]

open access: yesApplied and Environmental Microbiology, 1995
Pseudomonas sp. strain F274, previously shown to catabolize fluorene via fluorenone and its angular dioxygenation, 2(prm1),3(prm1)-dihydroxy-2-carboxybiphenyl, phthalate, and protocatechuate, was examined for its ability to transform substituted fluorenes and S- and N-heterocyclic analogs.
M, Grifoll, S A, Selifonov, P J, Chapman
openaire   +2 more sources

Discovery of Stealthin Derivatives and Implication of the Amidotransferase FlsN3 in the Biosynthesis of Nitrogen-Containing Fluostatins

open access: yesMarine Drugs, 2019
Diazobenzofluorene-containing atypical angucyclines exhibit promising biological activities. Here we report the inactivation of an amidotransferase-encoding gene flsN3 in Micromonospora rosaria SCSIO N160, a producer of fluostatins.
Chunshuai Huang   +6 more
doaj   +1 more source

Flash Pyrolysis – Synthetic and Mechanistic Aspects

open access: yesCHIMIA, 1977
Some examples of synthetically useful flash pyrolysis reactions are presented, and the reaction mechanisms are discussed. Cyanocyclopentadienes, -indenes, and -pyrroles are produced by pyrolysis of the appropriate triazoloarenes or isatins, or as the ...
Curt Wentrup
doaj   +1 more source

Bioactive fluorenes. part I. Synthesis, pharmacological study and molecular docking of novel dihydrofolate reductase inhibitors based-2,7-dichlorofluorene

open access: yesHeliyon, 2019
In this study, a new series of 2,7-dichloro-4-(2-substituted-amino acetyl)fluorene derivatives were synthesized, characterized and evaluated for their antimicrobial activity and screened for cytotoxic activity against human lung carcinoma (A-549) and ...
Essam M. Hussein   +6 more
doaj   +1 more source

Diatom aggregation when exposed to crude oil and chemical dispersant: Potential impacts of ocean acidification.

open access: yesPLoS ONE, 2020
Diatoms play a key role in the marine carbon cycle with their high primary productivity and release of exudates such as extracellular polymeric substances (EPS) and transparent exopolymeric particles (TEP). These exudates contribute to aggregates (marine
Jennifer L Genzer   +6 more
doaj   +1 more source

The Role of Ultra‐Thin Buffer Layers for Achieving Ultra‐Low Dark Currents in Single‐Component Organic Photodetectors

open access: yesAdvanced Functional Materials, EarlyView.
Here, SubNc single‐component organic photodiodes (SC‐OPDs) are investigated, which achieve highly competitive performance metrics, including high EQE, ultra‐low JD, and high specific detectivity (D*). This study emphasizes the critical role of an organic buffer layer in studying the interface energetics and effects to achieve state‐of‐the‐art ...
Anncharlott Kusber   +12 more
wiley   +1 more source

Cyclic Olefin Copolymers as Versatile Materials for Advanced Engineering Applications

open access: yesAdvanced Functional Materials, EarlyView.
Cyclic olefin copolymers (COCs) are presented as highly versatile materials combining tunable synthesis, excellent optical properties, and mechanical robustness. Their potential spans microfluidics, bioengineering, and advanced electronics, while emerging self‐healing and sustainable solutions highlight future opportunities.
Giulia Fredi   +3 more
wiley   +1 more source

Mitochondria‐Damaging Self‐Reporting Probe for Cancer Therapy

open access: yesAngewandte Chemie, EarlyView.
We developed a class of self‐reporting cationic chemotherapeutic probes that selectively induce mitochondrial damage and apoptosis in cancer cells. Their unique mitochondria‐to‐nucleus fluorescence migration enables real‐time visualization of the therapeutic process. ABSTRACT Mitochondrial damage induced by chemotherapeutic agents through disruption of
Hai Xu   +10 more
wiley   +2 more sources

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