Results 31 to 40 of about 262,034 (273)

Implantable Photonic Neural Probes with 3D-Printed Microfluidics and Applications to Uncaging [PDF]

open access: yes, 2023
Advances in chip-scale photonic-electronic integration are enabling a new generation of foundry-manufacturable implantable silicon neural probes incorporating nanophotonic waveguides and microelectrodes for optogenetic stimulation and electrophysiological recording in neuroscience research. Further extending neural probe functionalities with integrated
arxiv   +1 more source

Avaliação da viabilidade de intestino delgado com isquemia experimental pelo uso de fluoresceína sódica em eqüinos Evaluation of the small intestine viability with experimental ischemia by the use of sodic fluorescein in horses

open access: yesCiência Rural, 1997
Com o objetivo de testar o sal sódico de fluoresceína na indicação da viabilidade intestinal em casos de processos isquêmicos do intestino delgado de eqüinos, desenvolveu-se um modelo isquêmico através de ligadura artério-venosa durante 120 minutos ...
Augusto Sampaio, Ney Luis Pippi
doaj   +1 more source

Crystal structure of 4′-allyl-4,5,6,7,2′,7′-hexachlorofluorescein allyl ester unknown solvate

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2018
In the title compound, 4′-allyl-4,5,6,7,2′,7′-hexachlorofluorescein allyl ester {systematic name: prop-2-en-1-yl 2,3,4,5-tetrachloro-6-[2,7-dichloro-6-hydroxy-3-oxo-4-(prop-2-en-1-yl)-3H-xanthen-9-yl]benzoate}, C26H14Cl6O5, accompanied by unknown solvate
Lili Wang   +2 more
doaj   +1 more source

Squeezed Light Induced Two-photon Absorption Fluorescence of Fluorescein Biomarkers [PDF]

open access: yesAppl. Phys. Lett. 116, 254001 (2020), 2019
Two-photon absorption (TPA) fluorescence of biomarkers has been decisive in advancing the fields of biosensing and deep-tissue in vivo imaging of live specimens. However, due to the extremely small TPA cross section and the quadratic dependence on the input photon flux, extremely high peak-intensity pulsed lasers are imperative, which can result in ...
arxiv   +1 more source

Resection of gliomas by intraoperative high⁃field MRI combined with fluorescence⁃ guided

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2021
Objective To investigate the efficacy and safety of intraoperative high⁃field MRI combined with fluorescence⁃guided glioma resection. Methods A total of 53 patients with glioma admitted to The Fisrt Bethune Hospital of Jilin University from June 2017 to ...
DONG Ze⁃ping   +4 more
doaj   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

Tracking of a Fluorescent Dye in a Freshwater Lake with an Unmanned Surface Vehicle and an Unmanned Aircraft System

open access: yesRemote Sensing, 2018
Recent catastrophic events in our oceans, including the spill of toxic oil from the explosion of the Deepwater Horizon drilling rig and the rapid dispersion of radioactive particulates from the meltdown of the Fukushima Daiichi nuclear plant, underscore ...
Craig Powers   +2 more
doaj   +1 more source

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

open access: yesMolecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita   +1 more
wiley   +1 more source

Optic Disc Melanocytoma: A Case Report and Review

open access: yesJournal of Pediatrics Review, 2021
Introduction: Melanocytoma is a rare benign stationary tumor that usually appears as a pigmented lesion on the optic disk. Optic Disc Melanocytoma (ODM) can compress the optic nerve or undergo necrosis, leading to ischemic axonal loss and visual field ...
Ali Ahmadzadeh Amiri   +2 more
doaj  

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

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