Results 161 to 170 of about 81,185 (328)

Rapid Microfluidic Drug Sensitivity Testing Within 5 Days Using Minimal Clinical Tumor Samples

Advanced Science, EarlyView.
This study develops the air‐punched fabrication approach for nanoliter‐scale microcavity arrays with ultra‐smooth microcavity surfaces, with which rapid formation and 3D culture of tumor cell spheroids from small numbers of cell samples, as well as high‐throughput drug sensitivity testing can be achieved within 5 days.
Yi‐Xue Chen, Yi Zhang, Yu‐Jie Yan, Meng‐Ting Zhang, Jian‐Bo Chen, Yi‐Rong Jiang, Jie Wu, Hui‐Feng Wang, Jian‐Zhang Pan, Zhi‐Gang Chen, Jian Huang, Qun Fang   +11 more
wiley   +1 more source

Harnessing fluorescent probes for molecular diagnosis and theranostics of atherosclerosis. [PDF]

Drug Deliv
Mao X, Zhao X, Ni Z, Xu X, Liu Q, Qu P.
europepmc   +1 more source

Beyond Catalytic Therapy: Copper‐Paeonol Nanozymes Disrupt Fascin‐Mediated Actin Bundling to Suppress Tumor Growth and Metastasis

Advanced Science, EarlyView.
Copper‐paeonol nanozymes target tumor‐specific reactive oxygen species generation and disrupt fascin‐mediated actin bundling, effectively suppressing tumor growth and metastatic colonization. Abstract Fascin, an actin‐bundling protein universally upregulated in metastatic tumors, drives tumor migration and invasion by promoting filopodia and ...
Peiying Zhang, Huajun Li, Yisen Wang, Jie Xiang, Lei Fan, Shengzhe Zhang, Lizeng Gao, Hua Dai, Juqun Xi   +8 more
wiley   +1 more source

Néhány emlősállat állalatti nyálmirigyéből (Gl. submaxillaris) leírt „világos” és „sötét” sejtek értékelése mucopolysaccharid reagensek segítségével [PDF]

Vágás, Endre
core   +3 more sources

An <i>In Vivo</i> Fluorescence Image Analysis Tool for Esterase Activity Quantification in <i>Daphnia</i>: Using Calcein AM in Ecotoxicological Studies. [PDF]

Environ Sci Technol
Perez-Liñan A, Abele C, Pierozan P, Breitholtz M, Karlsson O.   +4 more
europepmc   +1 more source

Fluorescein Punctate Staining Traced to Superficial Corneal Epithelial Cells by Impression Cytology and Confocal Microscopy [PDF]

, 2011
Maryam Mokhtarzadeh, Richard Casey, Ben J. Glasgow   +2 more
openalex   +1 more source

Bimetallic Peroxide Nanocomposites‐Driven Redox Dyshomeostasis to Activate Sequential Cuproptosis and Pyroptosis for Amplified Tumor Immunotherapy

Advanced Science, EarlyView.
Hyaluronic acid‐modified bimetallic peroxide nanocomposites (MgO2‐CuO2@HA) are designed for synergistic tumor therapy. The nanocomposites release Mg2+, H2O2, and Cu2+ in tumor cells, induce cuproptosis via Cu+‐mediated protein aggregation, and activate pyroptosis through caspase‐1/gasdermin D pathways for inducing immunogenic cell death, collectively ...
Guanting He, Haixia Zhu, Peipei Kang, Lili Feng, Chenghao Yu, Yanlin Zhu, Bin Liu, Zhengxiao Guo, Piaoping Yang   +8 more
wiley   +1 more source

A borindolizine platform for the design of fluorophores with tunable emissions. [PDF]

Chem Sci
Apte CN, Heller NW, Huang BZ, Marr A, Jorner K, Aspuru-Guzik A, Yudin AK.   +6 more
europepmc   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Determination of the phloem transport pathways and destination of photosynthates in soybean using autoradiography and fluorescent tracer imaging. [PDF]

Plant Signal Behav
Kaiho-Soma A, Kurita Y, Kobayashi NI, Nakanishi TM, Tanoi K.   +4 more
europepmc   +1 more source