Results 211 to 220 of about 40,790 (312)

Oocyte Age‐Dependent DNA Damage Can Be Reverted by the DNA Repair Competent Karyoplasm of Young Oocytes

Aging Cell, EarlyView.
As females age, oocyte chromosomal aberrations and DNA damage increase in frequency; this condition is believed to be irreversible. By exposing the aged oocyte nuclei to nuclear factors from young oocytes, the negative effects can be effectively suppressed, restoring their developmental competence. ABSTRACT Mammalian fully grown oocytes are believed to
Nataliia Dudko, Tereza Ilcikova, Natalie Novotna, Marta Czernik, Pasqualino Loi, Josef Fulka Jr., Pritha Bhattacharjee, Raffaella Santoro, Helena Fulka   +8 more
wiley   +1 more source

A pixel‐based likelihood framework for analysis of fluorescence recovery after photobleaching data [PDF]

, 2008
Jenny K. Jonasson, Niklas Lorén, P. Olofsson, Magnus Nydén, Mats Rudemo   +4 more
openalex   +1 more source

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Analyses of the Dynamic Properties of Nuclear Lamins by Fluorescence Recovery After Photobleaching (FRAP) and Fluorescence Correlation Spectroscopy (FCS). [PDF]

Methods Mol Biol, 2016
Takeshi S, Pack CG, Goldman RD.
europepmc   +1 more source

Fluorescence recovery after photobleaching reveals different behaviour of tropomyosin isoforms Tpm3.1 and Tpm4.2 in dendritic spines [PDF]

Tamara Tomanić, Holly Stefen, Esmeralda Parić, Arthur Chien, Thomas Fath   +4 more
openalex   +1 more source

Liquid–Liquid Phase Separation in Major Hallmarks of Cancer

Cell Proliferation, EarlyView.
Aberrant condensates formed through phase separation are involved in the dysregulation of various critical cellular processes, including genome stability, transcriptional regulation and signal transduction, thereby promoting malignant transformation and the acquisition of multiple cancer hallmarks.
Chen‐chen Xie, Ting Wang, Xin‐ran Liu, Yan Wang, Qin Dang, Tian Ding, Jia‐qi Xu, Xian‐jun Yu, Hai Lin, Xiao‐wu Xu, Yi Qin   +10 more
wiley   +1 more source

Diffusion of macromolecules in cheeses is affected by solute size and cheese structure : a Fluorescence Recovery After Photobleaching (FRAP) approach

, 2014
Anne Laure Chapeau, Juliana Valle Costa Silva, Anne Thierry, Valérie Gagnaire Soumet, Juliane Floury   +4 more
openalex   +1 more source

CDKL5 regulates the initiation of retrograde axonal transport through CLIP170–dynactin complex formation

The FEBS Journal, EarlyView.
Activation of CLIP170 by CDKL5 in wild‐type (WT) cells promotes its open conformation and association with tyrosinated microtubule (MT) plus‐ends (+), where it works as a docking site to recruit the dynactin–dynein–cargo complex, promoting the initiation of retrograde transport. In knock‐out (KO) neurons, CLIP170 is mainly present in a closed (inactive)
Serena Baldin, Clara Carmone, Giorgia Valetti, Roberta De Rosa, Isabella Barbiero   +4 more
wiley   +1 more source

Polar‐localized EXO70G1 regulates root development in Arabidopsis thaliana

Journal of Integrative Plant Biology, EarlyView.
The putative exocyst subunit EXO70G1 exhibits apical‐basal polarity in Arabidopsis root cells; this polarity stabilizes membrane domains to facilitate targeting of the auxin transporter PIN‐FORMED2 during root development. ABSTRACT Cellular asymmetry, which represents a fundamental characteristic of cell polarity, is prominently illustrated by the ...
Juan Li, Zhendong Liu, Lixue Gong, Shuju Zhao, Qing Lu, Shan Gao, Su Jiang, Xiaonan Liu, Long Ma, Guangyou Duan, Dayong Cui, Shipeng Li   +11 more
wiley   +1 more source

Imaging malaria parasites across scales and time

Journal of Microscopy, EarlyView.
Abstract The idea that disease is caused at the cellular level is so fundamental to us that we might forget the critical role microscopy played in generating and developing this insight. Visually identifying diseased or infected cells lays the foundation for any effort to curb human pathology.
Julien Guizetti
wiley   +1 more source