Results 191 to 200 of about 55,338 (292)
Coacervate‐Mediated Lysosome‐Targeting Antibody Delivery for Protein Degradation
Advanced Science, Volume 13, Issue 25, 4 May 2026.Targeting coacervates to the lysosome in the cytoplasm is a challenge. Here, we convert a tetrapeptide into lysosome‐targeting, membrane‐translocating coacervates. The lysosome‐sorting peptide coacervates facilitate coacervate‐mediated delivery of antibody antigen complexes and a PROTAC compound to the lysosome for the targeted degradation of cancer ...
Dingdong Yuan +7 more
wiley +1 more source
Nucleation Kinetics Reveals a Distinct Biological Function Space of Biomolecular Condensates
Advanced Science, Volume 13, Issue 26, 8 May 2026.This study utilizes microfluidics to quantify the nucleation rates of dense liquid phases within dilute solutions and of the reverse process, in which dilute voids nucleate inside condensates. The interfacial tension is identified as the key determinant of both processes.
Leif‐Thore Deck +5 more
wiley +1 more source
Advanced Science, Volume 13, Issue 26, 8 May 2026.CDK5RAP2 associates with the kinesin HSET and forms co‐condensates. HSET motors drive the directional transport of CDK5RAP2 condensates toward microtubule minus ends. During mitosis, HSET self‐assembly further stabilizes clustered centrosomes, thereby enabling pseudo‐bipolar spindle formation in cancer cells with supernumerary centrosomes. Upon mitotic
Po‐Pang Chen +11 more
wiley +1 more source
Fluorescence recovery after photobleaching investigation of protein transport and exchange in chromatographic media. [PDF]
J Chromatogr A, 2014 Traylor SJ +4 more
europepmc +1 more source
A method improving the accuracy of fluorescence recovery after photobleaching analysis.
Biophysical Journal, 2008 Peter Jönsson +3 more
semanticscholar +1 more source
Aggregate, Volume 7, Issue 5, May 2026.The self‐assembly of carbon dots, which enables precise control over their macroscopic architectures and collective properties, profoundly enhances their functionality. This review systematically summarizes the field through four key aspects—morphology control, luminescence modulation, assembly mechanisms, and advanced applications—and thereby offers a
Kai Chen +5 more
wiley +1 more source
Measurement of three-dimensional anisotropic diffusion by multiphoton fluorescence recovery after photobleaching. [PDF]
Ann Biomed Eng, 2014 Shi C, Cisewski SE, Bell PD, Yao H.
europepmc +1 more source
Plasma Membrane‐Promoted Aggregation of BODIPY Dimers Enables Live‐Cell Super‐Resolution Imaging
Aggregate, Volume 7, Issue 5, May 2026.BODIPY dimers are introduced as membrane probes exhibiting dynamic, environment‐dependent intermolecular interactions within lipid bilayers. Transient aggregation between molecules drives switching between open, H‐aggregated, and J‐aggregated states, enabling efficient blinking. This behavior allows dual‐color imaging, with green emission outlining the
Sonia Pfister +3 more
wiley +1 more source