Results 221 to 230 of about 40,790 (312)

Microfluidic live‐cell imaging of Aspergillus fumigatus and Candida albicans hyphal growth treated with AmBisome and Caspofungin

open access: yesJournal of Microscopy, EarlyView.
Abstract Hyphal forms of human pathogenic fungi cause invasive disease in humans, but the hyphal response to antifungals is understudied. In the major fungal pathogens Aspergillus fumigatus and Candida albicans, we used microfluidic‐coupled, fluorescence‐mediated live‐cell imaging to capture the real‐time responses of fungal hyphae to clinical ...
D. D. Thomson   +3 more
wiley   +1 more source

Starch synthesis in Brachypodium distachyon endosperm occurs in dynamic, connected amyloplast compartments

open access: yesNew Phytologist, EarlyView.
Summary The morphology of starch granules is a major determinant of the functional and nutritional properties of starch and is highly variable among cereal species. Much of this morphological variation stems from differences in the spatial and temporal patterns of starch granule initiation in amyloplasts during grain development.
Lara Esch   +6 more
wiley   +1 more source

Localising enzymes to biomolecular condensates increases their accumulation and benefits engineered metabolic pathway performance in Nicotiana benthamiana

open access: yesPlant Biotechnology Journal, EarlyView.
Summary The establishment of Nicotiana benthamiana as a robust biofactory is complicated by issues such as product toxicity and proteolytic degradation of target proteins/introduced enzymes. Here we investigate whether biomolecular condensates can be used to address these problems. We engineered biomolecular condensates in N.
Anya L. Lindström Battle   +3 more
wiley   +1 more source

Transgene‐Free, Gene‐Edited Cavendish Bananas (Musa acuminata, AAA)

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Global consumer acceptance of gene‐edited food crops is increasing with new breeding technologies that can modify the genome without foreign DNA integration. Here, we report an Agrobacterium‐based system for transgene‐free, gene editing of the banana cultivar, Cavendish.
Maiko Kato   +6 more
wiley   +1 more source

Mathematical model of the zebrafish ventricular cardiomyocyte action potential and calcium transient

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This study presents the development and validation of the first biophysically detailed computational model of the zebrafish ventricular action potential (AP). The model is based on a human cardiomyocyte framework and reparameterized using published and newly generated patch‐clamp recordings of zebrafish ionic currents.
Ludovica Cestariolo   +5 more
wiley   +1 more source

Live-cell images of fluorescence recovery after photobleaching (FRAP) experiments in the strain expressing FgPin3-GFP.

open access: green
Yakubu Saddeeq Abubakar (5558399)   +6 more
openalex   +1 more source

Efficient in vivo targeting of the myocardial scar using Moloney murine leukaemia virus complexed with nanoparticles

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The complexation of Moloney murine leukaemia virus (MMLV) with magnetic nanoparticles (MNP) greatly enhanced the transduction of (myo)fibroblasts (FB), when applied in a magnetic field, both in vitro and in vivo in cryoinjured mice.
Timo Mohr   +11 more
wiley   +1 more source

Live-cell images of fluorescence recovery after photobleaching (FRAP) experiments in the strain expressing FgRvs167-GFP.

open access: green
Yakubu Saddeeq Abubakar (5558399)   +6 more
openalex   +1 more source

Neuromuscular junction instability with inactivity: morphological and functional changes after 10 days of bed rest in older adults

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This figure summarises the study of neuromuscular junction (NMJ) changes in 10 older males following a 10 day bed rest period. Baseline (BR0) and post‐bed rest (BR10) assessments were conducted using intramuscular EMG (iEMG) to measure NMJ transmission. At BR0 and BR10, muscle biopsies were obtained to analyse NMJ morphology, and
Evgeniia Motanova   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy