Results 111 to 120 of about 484,163 (235)

Fluorescent antibody technique in malaria [PDF]

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1968
Kielmann, A., Weiss, N.
openaire   +3 more sources

AlignAb: Pareto-Optimal Energy Alignment for Designing Nature-Like Antibodies [PDF]

arXiv
We present a three-stage framework for training deep learning models specializing in antibody sequence-structure co-design. We first pre-train a language model using millions of antibody sequence data. Then, we employ the learned representations to guide the training of a diffusion model for joint optimization over both sequence and structure of ...
arxiv  

dyAb: Flow Matching for Flexible Antibody Design with AlphaFold-driven Pre-binding Antigen [PDF]

arXiv
The development of therapeutic antibodies heavily relies on accurate predictions of how antigens will interact with antibodies. Existing computational methods in antibody design often overlook crucial conformational changes that antigens undergo during the binding process, significantly impacting the reliability of the resulting antibodies.
arxiv  

Cellular delivery of antibodies: effective targeted subcellular imaging and new therapeutic tool [PDF]

, 2010
It is already more than a century since the pioneering work of the Nobel Laureate Ehrlich gave birth to the side chain theory1, which helped to define antibodies and their ability to target specific biological sites.
Andrew L. Lewis, Giuseppe Battaglia, Irene Canton, Marzia Massignani, Nicholas J. Warren, Nisa Patikarnmonthon, Steven P. Armes   +6 more
core   +1 more source

A Recommender System based on the Immune Network [PDF]

Proceedings of the IEEE Congress on Evolutionary Computation (CEC 2002), pp 807-813, Honolulu, USA, 2002, 2008
The immune system is a complex biological system with a highly distributed, adaptive and self-organising nature. This paper presents an artificial immune system (AIS) that exploits some of these characteristics and is applied to the task of film recommendation by collaborative filtering (CF).
arxiv  

A vital dye analysis of the timing and pathways of avian trunk neural crest cell migration [PDF]

, 1989
To permit a more detailed analysis of neural crest cell migratory pathways in the chick embryo, neural crest cells were labelled with a nondeleterious membrane intercalating vital dye, DiI.
Bronner-Fraser, Marianne E., Fraser, Scott E., Serbedzija, George N.   +2 more
core  

Spectral imaging in preclinical research and clinical pathology. [PDF]

, 2012
Spectral imaging methods are attracting increased interest from researchers and practitioners in basic science, pre-clinical and clinical arenas. A combination of better labeling reagents and better optics creates opportunities to detect and measure ...
Beechem, Joseph, Levenson, Richard, McNamara, George   +2 more
core  

Cultural methods of detection for microorganisms: recent advances and successes [PDF]

, 1997
Most microbiological methods require culture to allow organisms to recover or to selectively increase, and target organisms are identified by growth on specific agar media.
Jian, X., Watkins , J.
core  

Diagnostic virology. [PDF]

, 1987
Diagnostic virology services are increasingly available and pertinent as the number of useful antiviral agents grows. In this article, current methods of diagnosis are reviewed with special emphasis on rapid procedures.
Drew, WL
core  

Study on the value of detecting early secretory antigenic target-6 in cerebrospinal fluid monocytes by laser scanning confocal microscopy techniques in the early diagnosis of tuberculous meningitis

Chinese Journal of Contemporary Neurology and Neurosurgery, 2016
Objective To explore the value of detecting early secretory antigenic target-6 (ESAT-6) in cerebrospinal fluid (CSF) monocytes by laser scanning confocal microscopy (LSCM) techniques in early diagnosis of tuberculous meningitis (TBM), and to find a ...
Mei-jie LI, Yue-li ZOU, Jun-ying HE
doaj