Results 111 to 120 of about 416,920 (380)

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

Case for diagnosis Caso para diagnóstico

Anais Brasileiros de Dermatologia, 2012
We report a clinical case of a rare variant of pemphigus - pemphigus herpetiformis - which combines the clinical features of dermatitis herpetiformis with the immunological findings of pemphigus.
Iolanda Conde Fernandes, Madalena Sanches, Rosário Alves, Manuela Selores   +3 more
doaj   +1 more source

Acidic microenvironment plays a key role in human melanoma progression through a sustained exosome mediated transfer of clinically relevant metastatic molecules [PDF]

, 2018
Background: Microenvironment cues involved in melanoma progression are largely unknown. Melanoma is highly influenced in its aggressive phenotype by the changes it determinates in its microenvironment, such as pH decrease, in turn influencing cancer cell
A Albini, A Lardner, Alessandra Carè, AR Hess, Bok Hong, C Coscia, Carla Raggi, CC Jiang, CP Lai, Cristiana Zanetti, D Hanahan, E Alegre, E Willms, EK Rofstad, Elin J Ekström, Elisabetta Pizzi, Fabrizio Mattei, Federica Felicetti, Federica Fratini, G Helmlinger, G Raposo, H Mizuno, H Peinado, I Lazar, I Parolini, IF Robey, Isabella Parolini, J Kowal, J Lotvall, J Niu, J Skog, J Webber, Jessica Lamberti, JL Hood, JL Hood, JL Wike-Hooley, JM Graham, JR Knutson, K Al-Nedawi, Katia Fecchi, Luca Fantozzi, Luca Pasquini, M Colombo, M Logozzi, Massimo Sanchez, Massimo Sargiacomo, MR Muhsin-Sharafaldine, N Raghunand, O WARBURG, P Vaupel, R Valenti, RE Moellering, Rossella Puglisi, S Dror, S Dutta, S Peppicelli, SK Huang, Stefania D’Atri, T Fiaschi, T Fukamachi, T Groot Kormelink, T Kobayashi, V Estrella, V Pospichalova, V Vukovic, XY Yam, Y Ishihama, Zaira Boussadia   +67 more
core   +10 more sources

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Análise de exames de imunofluorescência direta para o diagnóstico de tracoma

Revista de Saúde Pública
Para confirmação de foco de tracoma em locais onde não existiam casos anteriormente relatados, a Secretaria de Estado da Saúde preconiza a realização de exames laboratoriais principalmente pelo fato da doença ter sido considerada erradicada no Estado de ...
Norma H. Medina, Rosana M. Gentil, Márcia Caraça, César K. Suzuki, Heloísa H. B. Melles   +4 more
doaj  

Expression and significance of p120ctn isoforms in lung squamous cell carcinomas

Chinese Journal of Lung Cancer, 2008
Background and Objective It has been proven that p120ctn plaied an important role in cell adhesion and correlates with tumorigenesis significantly, the aim of this work is to investigate the expression of p120ctn(p120 catenin) isoform proteins in lung ...
Enhua WANG, Yan WANG, Yang LIU, Yuan MIAO   +3 more
doaj  

Immunofluorescence and its application in dermatopathology with oral manifestations: Revisited

Journal of Orofacial Sciences, 2013
The use of fluorescence probes the field of cell and molecular biology. Immunofluorescence is a molecular method for detection of antigen or antibody in a tissue section/serum sample. Although histopathology remains gold standard for most of auto immune,
R S Arvind Babu, P Chandrasekar, K Lalith Prakash Chandra, G Sridhar Reddy, K Krian Kumar, B V Ramana Reddy   +5 more
doaj   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Detection of Air-borne Pasteurella tularensis Using the Fluorescent Antibody Technique [PDF]

, 1961
R. Jaeger, R. O. Spertzel, Ralph W. Kuehne   +2 more
openalex   +2 more sources

Preliminary Study of In Vivo Formed Dental Plaque Using Confocal Microscopy and Scanning Electron Microscopy

Frontiers in Dentistry, 2009
Objective: Confocal laser scanning microscopy (CLSM) is relatively a new light microscopical imaging technique with a wide range of applications in biological sciences. primary value of CLSM for the biologist is its ability to provide optical sections
KA. Al-Salihi , NABA. Tarmidzi   +1 more
doaj