Results 41 to 50 of about 427,237 (379)

Nanoscale integration of single cell biologics discovery processes using optofluidic manipulation and monitoring. [PDF]

open access: yes, 2019
The new and rapid advancement in the complexity of biologics drug discovery has been driven by a deeper understanding of biological systems combined with innovative new therapeutic modalities, paving the way to breakthrough therapies for previously ...
Chen, Ching   +17 more
core   +1 more source

Paraneoplastic Pemphigus Presenting as Toxic Epidermal Necrolysis: A Case Report

open access: yesNepal Journal of Dermatology, Venereology & Leprology, 2018
Polymorphous skin lesions have classically been described in paraneoplastic pemphigus (PNP), but it can present as toxic epidermal necrolysis (TEN) though this type of presentation is extremely rare.
Jignaben K Padhiyar   +6 more
doaj   +3 more sources

Differentiation of ruminant transmissible spongiform encephalopathy isolate types, including bovine spongiform encephalopathy and CH1641 scrapie [PDF]

open access: yes, 2010
With increased awareness of the diversity of transmissible spongiform encephalopathy (TSE) strains in the ruminant population, comes an appreciation of the need for improved methods of differential diagnosis. Exposure to bovine spongiform encephalopathy (
Bossers, A.   +5 more
core   +2 more sources

Citologia de Tzanck: redescobrindo uma antiga ferramenta diagnóstica Tzanck smears: an old but useful diagnostic tool

open access: yesAnais Brasileiros de Dermatologia, 2009
A citologia de Tzanck consiste em método simples e confiável para o diagnóstico de dermatoses virais, parasitárias, autoimunes e tumorais. Para exemplificar o emprego do teste de Tzanck em lesões vésico-bolhosas, um caso de pênfigo vulgar é descrito ...
Moema Mignac Cumming Brito   +4 more
doaj   +1 more source

Approaches to overcome flow cytometry limitations in the analysis of cells from veterinary relevant species [PDF]

open access: yes, 2020
BACKGROUND: Flow cytometry is a powerful tool for the multiparameter analysis of leukocyte subsets on the single cell level. Recent advances have greatly increased the number of fluorochrome-labeled antibodies in flow cytometry.
Debes, Gudrun F.   +2 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Etiological diagnosis reduces the use of antibiotics in infants with bronchiolitis

open access: yesClinics, 2012
OBJECTIVE: Acute bronchiolitis is a leading cause of infant hospitalization and is most commonly caused by respiratory syncytial virus. Etiological tests are not required for its diagnosis, but the influence of viral screening on the therapeutic approach
Ângela Esposito Ferronato   +4 more
doaj   +1 more source

Comparative evaluation of some techniques used for detection of rabies virus

open access: yesOpen Veterinary Journal, 2023
Background: Neurotropic viruses in the family Rhabdoviridae, genus Lyssavirus, are what cause rabies, an acute, progressive, and highly lethal encephalomyelitis.
Dalia Nasr Hegazy   +4 more
doaj   +1 more source

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

open access: yesFEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera   +4 more
wiley   +1 more source

Single-cell western blotting. [PDF]

open access: yes, 2014
To measure cell-to-cell variation in protein-mediated functions, we developed an approach to conduct ∼10(3) concurrent single-cell western blots (scWesterns) in ∼4 h.
Herr, Amy E   +5 more
core   +2 more sources

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