Results 81 to 90 of about 223,239 (351)

Targeting the insulin growth factor-1 receptor with fluorescent antibodies enables high resolution imaging of human pancreatic cancer in orthotopic mouse models. [PDF]

, 2016
The goal of the present study was to determine whether insulin-like growth factor-1 receptor (IGF-1R) antibodies, conjugated with bright fluorophores, could enable visualization of pancreatic cancer in orthotopic nude mouse models. IGF-1R antibody (clone
Bouvet, Michael, Hoffman, Robert M, Lee, Jin Young, Park, Jeong Youp, Zhang, Yong   +4 more
core   +2 more sources

Deepening inside the pictorial layers of Etruscan sarcophagus of Hasti Afunei: An innovative micro-sampling technique for Raman/SERS analyses [PDF]

, 2019
The Hasti Afunei sarcophagus is a large Etruscan urn, made up of two chalky alabaster monoliths. Dated from the last quarter of the third century BC, it was found in 1826 in the small town of Chiusi (Tuscany- Il Colle place) by a landowner, Pietro Bonci ...
Bianco, Armandodoriano, Bruno, Maurizio, Ciccola, Alessandro, Gagliano Candela, Rossella, Lombardi, Livia, Pellegrino, Lorella, Postorino, Paolo, Serafini, Ilaria   +7 more
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Fluorescent, Prussian Blue-Based Biocompatible Nanoparticle System for Multimodal Imaging Contrast

Nanomaterials, 2020
(1) Background. The main goal of this work was to develop a fluorescent dye-labelling technique for our previously described nanosized platform, citrate-coated Prussian blue (PB) nanoparticles (PBNPs). In addition, characteristics and stability of the PB
László Forgách, Nikolett Hegedűs, Ildikó Horváth, Bálint Kiss, Noémi Kovács, Zoltán Varga, Géza Jakab, Tibor Kovács, Parasuraman Padmanabhan, Krisztián Szigeti, Domokos Máthé   +10 more
doaj   +1 more source

Fluorescence efficiency of laser dyes

Journal of Research of the National Bureau of Standards Section A: Physics and Chemistry, 1976
The fluorescence efficiency of xanthene dyes, oxazine dyes, and 7-aminocoumarins is discussed. Relations with the molecular structure are pointed out and dependence on solvent and temperature is explained. Several new fluorescence standards are suggested.
openaire   +1 more source

Exploiting speckle correlations to improve the resolution of wide-field fluorescence microscopy [PDF]

, 2014
Fluorescence microscopy is indispensable in nanoscience and biological sciences. The versatility of labeling target structures with fluorescent dyes permits to visualize structure and function at a subcellular resolution with a wide field of view. Due to
Bertolotti, Jacopo, Lagendijk, Ad, Mosk, Allard P., van Putten, Elbert G., Vos, Willem L., Yilmaz, Hasan   +5 more
core   +4 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Directing liquid crystalline self-organization of rod-like particles through tunable attractive single tips

, 2019
Dispersions of rodlike colloidal particles exhibit a plethora of liquid crystalline states, including nematic, smectic A, smectic B, and columnar phases.
Grelet, Eric, Menegon, Mariana Oshima, Repula, Andrii, van der Schoot, Paul, Wu, Cheng   +4 more
core   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

ASYMMETRIC, WATER-SOLUBLE CYANINE DYES: SYNTHESIS AND FLUORESCENT PROBE FOR THE Fe3+ ION

Studia Universitatis Babes-Bolyai Chemia
Two known symmetric and four novel asymmetric water-soluble pentamethyl cyanine dyes were synthesized and fully characterized by IR, MS and NMR. These dyes exhibited good water solubility and possessed good stability at different pH environment.
Xinyu DUAN, Weijian LI , Yanan NIU, Aihong HAN   +3 more
doaj   +1 more source