Results 81 to 90 of about 218,447 (350)

Dual Role of Subphthalocyanine Dyes for Optical Imaging and Therapy of Cancer [PDF]

, 2018
This is the peer-reviewed version of the following article: van de Winckel, E., Mascaraque, M., Zamarrón, A., Juarranz de la Fuente, Á., Torres, T., & de la Escosura, A. (2018).
Escosura Navazo, Andrés de la, Juarranz de la Fuente, Ángeles, Mascaraque Checa, Marta, Torres Cebada, Tomás, van de Winckel, Eveline, Zamarrón, Alicia   +5 more
core   +1 more source

Fluorescent Dye Uptake By Platelets.

Experimental Biology and Medicine, 1967
SummaryThe uptake of the fluorescent dye euchrysine by human platelets is not affected by the aggregating agents ADP and adrenaline or by endotoxin, but is lost after exposure to anti-platelet and anti-red cell stroma serum. Granules of platelets fail to take up the dye at low temperatures and at an acid pH, both of these conditions being reversible ...
Cora L. Gott, John A. Shively
openaire   +2 more sources

Fluorescent dyes specific for quadruplex DNA [PDF]

Nucleic Acids Research, 1998
Fluorescent dyes which are specific for duplex DNA have found a wide range of applications from staining gels to visualization of chromosomes. Porphyrin dyes have been found which are highly fluorescent in the presence of quadruplex but not duplex DNA. These dyes may offer a route to the specific detection of quadruplex DNA under biologically important
Thomas L. Kawano, Philip H. Bolton, Haribabu Arthanari, Swarna Basu   +3 more
openaire   +3 more sources

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Fluorescent, Prussian Blue-Based Biocompatible Nanoparticle System for Multimodal Imaging Contrast

Nanomaterials, 2020
(1) Background. The main goal of this work was to develop a fluorescent dye-labelling technique for our previously described nanosized platform, citrate-coated Prussian blue (PB) nanoparticles (PBNPs). In addition, characteristics and stability of the PB
László Forgách, Nikolett Hegedűs, Ildikó Horváth, Bálint Kiss, Noémi Kovács, Zoltán Varga, Géza Jakab, Tibor Kovács, Parasuraman Padmanabhan, Krisztián Szigeti, Domokos Máthé   +10 more
doaj   +1 more source

Fluorescent nanoparticles for sensing

, 2020
Nanoparticle-based fluorescent sensors have emerged as a competitive alternative to small molecule sensors, due to their excellent fluorescence-based sensing capabilities.
Acosta, Alarcón-Angeles, Albertazzi, Aldewachi, Ali, Ali, Alivisatos, Amelia, Amin, Arai, Arcudi, Bae, Bagwe, Behnke, Berti, Bhattacharyya, Biteen, Bruchez, Byrappa, Cai, Cao, Carregal-Romero, Chai, Chandra, Chen, Chen, Chen, Chen, Chen, Chen, Choi, Chu, Colom, De Luca, del Mercato, del Mercato, Derr, Dhenadhayalan, Diaz-Diestra, Ding, Dmitriev, Dong, Duong, Duong, Enkin, Fehérvári, Fernández-Argüelles, Fong, Fu, Furukawa, Gao, Govindaraju, Guo, Ha, Halter, Herschel, Hines, Hornig, Hou, Hu, Huang, Huang, Huang, Iyer, Jelinek, Jeong, Jiang, Jimenez de Aberasturi, Jin, Kim, Kircher, Kong, Lakowicz, Lan, Lee, Lemon, Leobandung, Leonhardt, Lepore, Li, Li, Li, Li, Li, Li, Li, Li, Li, Li, Lim, Lin, Lin, Liu, Liu, Liu, Liu, Liu, López-Duarte, Ma, Ma, Medintz, Melnychuk, Miao, Monteiro, Naccarato, Nandi, Ng, Nie, Nooney, Ou, Pan, Pellegrino, Peng, Pompa, Potter, Qian, Qian, Qu, Rakovich, Rao, Reisch, Riccò, Riedinger, Ruedas-Rama, Saha, Samokhvalov, See, Shamirian, Shang, Shang, Shangguan, Shao, Shen, SMITH, Song, Stich, Stryer, Stöber, Su, Sun, Tang, Thiyagarajan, Toh, Ukeda, Valeur, Wang, Wang, Wang, Wang, Wang, Wang, Wang, Wang, Wei, Wen, Widengren, Wolfbeis, Wu, Wu, Wu, Wu, Wu, Xie, Xie, Xu, Xu, Yang, Yang, Ye, Yin, Yin, Yu, Yu, Yu, Zadran, Zeng, Zhang, Zhang, Zhang, Zhao, Zheng, Zhu, Zor, Zorman   +183 more
core   +1 more source

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

Molecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo, Marco Siringo, Alessandro Vici, Ann Zeuner, Orietta Gandini, Paola Gazzaniga, Chiara Nicolazzo   +6 more
wiley   +1 more source

J Fluorescence [PDF]

, 2005
The scope of this paper is to illustrate the need for an improved quality assurance in fluorometry. For this purpose, instrumental sources of error and their influences on the reliability and comparability of fluorescence data are highlighted for ...
Ebert, P., Engel, A., Hoffmann, K., Macdonald, R., Neukammer, J., Nietfeld, W., Nitschke, R., Resch-Genger, U.   +7 more
core   +2 more sources