Results 31 to 40 of about 3,257,828 (382)

Radiosynthesis, in vitro and preliminary in vivo evaluation of the novel glutamine derived PET tracers [18F]fluorophenylglutamine and [18F]fluorobiphenylglutamine

, 2020
INTRODUCTION: Glucose has been deemed the driving force of tumor growth for decades. However, research has shown that several tumors metabolically shift towards glutaminolysis.
Baguet, Tristan, Beyzavi, M. Hassan, De Lombaerde, Stef, De Vos, Filip, Descamps, Benedicte, Donche, Sam, Goethals, Ingeborg, Hu, Jiyun, Lambe, Patricia, Pauwelyn, Glenn, Piron, Sarah, Vanhove, Christian, Verhoeven, Jeroen   +12 more
core   +1 more source

Enzymatic transhalogenation of dendritic RGD peptide constructs with the fluorinase [PDF]

, 2016
We thank EPSRC and the Scottish Imaging Network (SINAPSE) for grants. DO’H thanks the Royal Society for a Wolfson Research Merit Award and ST is grateful to the John and Kathleen Watson Scholarship for financial support.
Fleming, Ian N., O’Hagan, David, Thompson, Stephen   +2 more
core   +1 more source

Fluorine-18: an untapped resource in inorganic chemistry [PDF]

Chemical Communications, 2018
Advances in the field of fluorine chemistry have been applied extensively to the syntheses of 18F-labelled organic compounds and radiopharmaceuticals.
Cassis Varlow, Cassis Varlow, Vadim Bernard-Gauthier, Vadim Bernard-Gauthier, Neil Vasdev, Neil Vasdev, Kenneth Dahl, Kenneth Dahl, Daniel Szames, Daniel Szames   +9 more
openaire   +3 more sources

Positron detection in silica monoliths for miniaturised quality control of PET radiotracers [PDF]

, 2016
We demonstrate the use of the miniaturised Medipix positron sensor for detection of the clinical PET radiotracer, [⁶⁸Ga]gallium-citrate, on a silica-based monolith, towards microfluidic quality control.
Alexander, Richard, Archibald, Stephen J., Brown, Nathaniel J., Maneuski, Dzmitry, O’Shea, Val, Pamme, Nicole, Pimlott, Sally L., Tarn, Mark D.   +7 more
core   +2 more sources

Carbon-11 and Fluorine-18 Labeled Amino Acid Tracers for Positron Emission Tomography Imaging of Tumors

Frontiers in Chemistry, 2018
Tumor cells have an increased nutritional demand for amino acids (AAs) to satisfy their rapid proliferation. Positron-emitting nuclide labeled AAs are interesting probes and are of great importance for imaging tumors using positron emission tomography ...
Aixia Sun, Xiang Liu, Ganghua Tang
semanticscholar   +1 more source

τBu₂SiF-Derivatized D₂-Receptor Ligands: The First SiFA-Containing Small Molecule Radiotracers for Target-Specific PET-Imaging [PDF]

, 2011
The synthesis, radiolabeling and in vitro evaluation of new silicon-fluoride acceptor (SiFA) derivatized D-2-receptor ligands is reported. The SiFA-technology simplifies the introduction of fluorine-18 into target specific biomolecules for Positron ...
Bartenstein, Peter, Höfner, Georg, Iovkova-Berends, Ljuba, Jurkschat, Klaus, Kostikov, Alexey, Rensch, Christian, Schirrmacher, Ralf, Wanner, Klaus Theodor, Wängler, Björn, Wängler, Carmen, Zöller, Thomas   +10 more
core   +2 more sources

A New Method for 18FDG generating using Geant4/ Gate7

Basic & Clinical Cancer Research, 2023
Fluorine 18-deoxyglucose is often used in Positron Emission Tomography devices. Positron Emission Tomography imaging is one of the useful tools which is used for cancer detection and its management.
Abuzar Shakeri, Ebrahim Heidari, Seyedeh Nasrin Hosseini Motlagh, Hamid Reza Vanaei   +3 more
doaj  

Detectability of colorectal neoplasia with fluorine-18-2-fluoro-2-deoxy-D-glucose positron emission tomography and computed tomography (FDG-PET/CT) [PDF]

, 2011
The purpose of this study was to analyze the detectability of colorectal neoplasia with fluorine-18-2-fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography (FDG-PET/CT). Data for a total of 492 patients who had undergone both PET/CT
A Katagiri, B Levin, BR Weston, CD Johnson, CG Fraser, D Ravizza, D Thorwarth, DF Halpenny, Eisuke Kaji, EM Kamel, EM Rohren, F Gutman, FA Sinicrope, H Pohl, Hideyuki Suzuki, J Czernin, JP Drenth, Jun Kato, Kazuhide Yamamoto, Keisuke Hori, KS Tagore, MB Tessem, MC Kouwen van, Mitsuhiro Akita, O Israel, PL Kei, R Meza, R Minamimoto, R Tatlidil, Reiji Higashi, S Friedland, S Halligan, S Kudo, S Kudo, S Tsuda, S Yasuda, Sakiko Hiraoka, Sakuma Takahashi, Shunsuke Saito, SS Shim, TF Imperiale, Tomoko Hirakawa, Toshio Uraoka, WS Samowitz, Y Zhao, Yoshihiro Okumura   +45 more
core   +1 more source

Synthesis of [ 18 F]fluoroethoxy‐benzovesamicol, a radiotracer for cholinergic neurons [PDF]

, 1993
Full experimental details are given for the preparation of [ 18 F]fluoroethoxy‐benzovesamicol, (−)‐( 2R, 3R )‐ trans ‐2‐hydroxy‐3‐(4‐phenylpiperidino)‐5‐(2‐[ 18 F]fluoroethoxy)‐1,2,3,4‐tetralin, a new fluorine‐18 labeled cholinergic neuron mapping agent ...
Altar, Block, Block, Chi, Dale, Efange, French, Hicks, Jerabek, Jung, Keisewetter, Kiesewetter, Kilbourn, Lemaire, Marien, Marshall, Moerlein, Mulholland, Mulholland, Mulholland, Mulholland, Mulholland, Mulholland, Plenevaux, Rogers, Rogers, Rogers, Rogers, Satymurthy, Shuie, Suehiro, Widen   +31 more
core   +1 more source

Radiosynthesis of [¹⁸F]-Labelled Pro-Nucleotides (ProTides)

Molecules, 2020
Phosphoramidate pro-nucleotides (ProTides) have revolutionized the field of anti-viral and anti-cancer nucleoside therapy, overcoming the major limitations of nucleoside therapies and achieving clinical and commercial success.
Alessandra Cavaliere, Katrin C. Probst, Stephen J. Paisey, Christopher Marshall, Abdul K. H. Dheere, Franklin Aigbirhio, Christopher McGuigan, Andrew D. Westwell   +7 more
doaj   +1 more source