Results 211 to 220 of about 15,492 (288)

LAG‐3+ Regulatory T Cells Suppress Effector Function of T Cells and Allow Their Proliferation Into Regulatory T Cells

open access: yesImmunology, Volume 177, Issue 2, Page 317-328, February 2026.
LAG‐3+ regulatory T cells suppress the effector but not the proliferative response of naïve cognate antigen‐specific CD4+ T cells in vivo. The suppressed T cells display upregulation of immune checkpoints and downregulation of pro‐inflammatory pathways with enhanced TCR signaling and reduced oxidative metabolism.
Avijit Dutta   +7 more
wiley   +1 more source

Modulation of Immune Cells by Aspirin During Pregnancy

open access: yesImmunology, Volume 177, Issue 2, Page 329-338, February 2026.
This study explores immune and haematological shifts in high‐risk pregnancies, noting lower haemoglobin and platelet levels linked to maternal risk factors. Th2 cell increases support gestational tolerance, while LDA use correlates with reduced cytotoxic NK CD56dim cells and elevated CD56bright NK and naïve Treg cells, suggesting enhanced immune ...
Ana Luísa Areia   +4 more
wiley   +1 more source

Three-Dimensional Trilineage Differentiation Conditions for Human Induced Pluripotent Stem Cells. [PDF]

open access: yesBioengineering (Basel)
Rahman MS   +7 more
europepmc   +1 more source

Nbeal2 Inactivation Triggers Abl1 Stabilisation and Dysregulated Subcellular Localisation of the Multi‐Drug‐Resistant Protein MDR1 (ABCB1) in Mast Cells

open access: yesImmunology, Volume 177, Issue 2, Page 355-369, February 2026.
(A) Proposed model for Abl1 degradation via Nbeal2. Nbeal2 interacts with Abl1 with its WDR domain. This results in proteasomal degradation by a yet unidentified ubiquitin ligase. Therefore, Nbeal2 inactivation stabilises Abl1, which supports mast cell (MC) degeneration. (B) In wt MCs, the Abl1 protein level is controlled by Nbeal2. Furthermore, Nbeal2
Raphaela Marquardt   +10 more
wiley   +1 more source

Tooth–bone attachment tissue is produced by cells with a mixture of odontoblastic and osteoblastic features in reptiles

open access: yesJournal of Anatomy, Volume 248, Issue 2, Page 251-268, February 2026.
Tooth attachment in vertebrates ranges from ligament‐based anchorage in mammals to direct fusion in many reptiles. In the veiled chameleon, we identified a transient cell population—termed ankyloblasts—at the tooth‐bone interface. These cells exhibit both odontoblast‐ and osteoblast‐like features.
M. Šulcová   +11 more
wiley   +1 more source

Unveiling long-range forces in light-harvesting proteins: Pivotal roles of temperature and light. [PDF]

open access: yesSci Adv
Perez-Martin E   +13 more
europepmc   +1 more source

Decoding UTROSCT heterogeneity: systematic clinicopathological evaluation combined with molecular profiling

open access: yesThe Journal of Pathology: Clinical Research, Volume 12, Issue 1, January 2026.
Abstract Uterine tumor resembling ovarian sex cord tumor (UTROSCT) constitutes an exceptionally rare histological subset of uterine mesenchymal neoplasms. While most cases have benign clinical behavior, a subset of UTROSCTs exhibits clinically aggressive behavior characterized by recurrence and metastasis.
Jing Yang   +6 more
wiley   +1 more source

Optimized full-spectrum flow cytometry panel for deep immunophenotyping of murine lungs. [PDF]

open access: yesCell Rep Methods
Baumann Z   +5 more
europepmc   +1 more source

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