Results 41 to 50 of about 17,088 (300)

Targeting Tex10 Overcomes Oxaliplatin Resistance by Competitively Disrupting the Non‐Canonical BAF Complex in Colorectal Cancer

Advanced Science, EarlyView.
This study reveals that Tex10 drives oxaliplatin resistance in colorectal cancer by competitively binding BRD9 to disrupt the ncBAF complex, thereby suppressing AMBRA1 transcription and ULK1‐mediated autophagy. Gemcitabine is identified as a direct Tex10 inhibitor that restores autophagy and overcomes resistance.
Ping Xu, Jie Huang, Xiaojin Gao, Lin Deng, Yanheng Deng, Denglu Wang, Chunlei Yu, Yunxiang Zhang, Jingdong Li, Xiaocong Xiang   +9 more
wiley   +1 more source

FLOW CYTOMETRY AS A MODERN ANALYTICAL TOOL IN BIOLOGY AND MEDICINE

Медицинская иммунология, 2014
. Flow cytometry is considered as a modern technology for fast measurements of cellular characteristics, their organelles, and processes occurring within them.
S. V. Khaidukov, A. V. Zurochka
doaj   +1 more source

Matrix Stiffness Enhances Odontogenic Differentiation of DPSCs through Membrane Curvature Protein Baiap2‐Modulated Exosome Release

Advanced Science, EarlyView.
Matrix stiffness softening is identified as a previously underappreciated feature in deep caries. Higher stiffness drives exosome release in dental pulp stem cells through a coordinated mechanism involving PI3K–AKT‐regulated Baiap2 and kinesin‐1, thereby promoting odontogenic differentiation.
Bilun Jin, Shaojie Dong, Yue Jia, Zhao Xu, Peiqi Liu, Zhaojing Ding, Yuxin Liao, Rui Zou, Jinsong Hu, Bo Cheng, Lin Niu   +10 more
wiley   +1 more source

Empleo de la técnica hibridación in situ fluorescente para visualizar microorganismos Use of fluorescence in situ hybridization technique to visualize microorganisms

Salud UIS, 2011
La hibridación in situ fluorescente (FISH), es una técnica que emplea sondas de oligonucleótidos marcadas con fluorocromos las cuales van dirigidas hacia secuencias específicas del ácido ribonucleico ribosomal (ARNr), lo que permite la identificación ...
Raúl Rodríguez Martínez
doaj  

Fluorochromes

, 2008
openaire   +2 more sources

Staining autoradiographs with the fluorochrome “33258” [PDF]

The Science of Nature, 1976
feuchtigkeitsempfindlich. Von der IridiumVerbindung konnten durch 800stfindiges Tempern bei 1000 ~ Einkristalle erhalten werden. In Tabelle 1 sind neben den pyknometrisch besfimmten Dichten die r6ntgenographischen Daten angegeben, die beim Lil,e3IrB2 aus Pr~izessionsaufnahmen, bei den beiden anderen Verbindungen aus Guinier-Aufnahmen ermittelt wurden ...
openaire   +2 more sources

Microfluorometric Investigations of Chromatin Structure - I. Evaluation of Nine DNA-Specific Fluorochromes as Probes of Chromatin Organization

, 1981
The ability of the highly condensed chromatin of small thymocyte nuclei and the more loosely organized chromatin of hepatocyte nuclei to interact with nine DNA-specific fluorochromes was assessed by microfluorometry.
Curtis, S. K., Cowden, R. R.
core   +1 more source

Rhoifolin Alleviates Ulcerative Colitis by Targeting NMNAT1 and Activating SIRT1‐FOXO1 Signaling to Enhance ILC3s Effector Function

Advanced Science, EarlyView.
Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang, Yishu Zhang, Sijia Feng, Xiaoqing Ma, Jiayi Feng, Junwei Wang, Jialin Gao, An Pan, Dapeng Wu, Kang Ding, Caijuan Zheng, Qi Lv, Lihong Hu   +12 more
wiley   +1 more source

Flow Cytometry for Estimating Plant Genome Size: Revisiting Assumptions, Sources of Variation, Reference Standards, and Best Practices

Journal of the American Society for Horticultural Science
Flow cytometry has been widely used to estimate relative and absolute genome sizes (DNA contents) of plants for more than 50 years. However, the accuracy of these estimates can vary widely because of many factors, including errors in the genome size ...
John Nix, Thomas G. Ranney, Nathan P. Lynch, Hsuan Chen   +3 more
doaj   +1 more source

Stress Hyperglycemia Drives CD4+ T Cell PANoptosis and Postoperative Organ Injury via Monocyte‐Derived Succinate

Advanced Science, EarlyView.
High glucose is linked to reduced succinate dehydrogenase activity in CD14+ monocytes, accompanied by succinate accumulation and extracellular release. Extracellular succinate exacerbates mitochondrial ROS production and mtDNA release in CD4+ T cells. Cytosolic mtDNA then activates Z‐DNA binding protein 1 (ZBP1) and engages ZBP1‐associated inflammatory
Shuai Zhao, Xuemei Miao, Wei Luo, Tao Liu, Yang Wang, Jiaying Li, Di Fu, Weiyun Shen, Yan Luo, Kang Chen, Ruping Dai, Hui Li   +11 more
wiley   +1 more source