Results 101 to 110 of about 129,172 (353)

The genetic basis of host preference and resting behavior in the major African malaria vector, Anopheles arabiensis [PDF]

, 2016
Malaria transmission is dependent on the propensity of Anopheles mosquitoes to bite humans (anthropophily) instead of other dead end hosts. Recent increases in the usage of Long Lasting Insecticide Treated Nets (LLINs) in Africa have been associated ...
Collier, T. J., Cornel, A.J., Eskin, E., Ferguson, H.M., Govella, N. J., Kang, E.Y., Kihonda, A., Kreppel, K.S., Lanzaro, G.C., Lee, Y., Main, B. J., Nieman, C.C., Weakley, A.M.   +12 more
core   +3 more sources

Portable Aptasensor Based on Parallel Rolling Circle Amplification for Tumor‐Derived Exosomes Liquid Biopsy

Advanced Science
Here, a separation‐free and label‐free portable aptasensor is developed for rapid and sensitive analysis of tumor‐derived exosomes (TEXs). It integrated a parallel rolling circle amplification (RCA) reaction, selective binding of metal ions or small ...
Yaqin He, Xianghu Zeng, Ying Xiong, Congcong Shen, Ke Huang, Piaopiao Chen   +5 more
doaj   +1 more source

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

Advanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu, Bo Qin, Zhuoyu Gu, Weizheng Ding, Xiaoming Chen, Kaishang Zhang, Yujin Qiao, Shuang Yuan, Song Zhao, Xiangnan Li, Peng Zhang   +10 more
wiley   +1 more source

ZSL Orchestrates Synaptonemal Complex Assembly as a Central Region Scaffold to Ensure Synapsis Fidelity and Crossover Control in Polyploid Meiosis

Advanced Science, EarlyView.
A central molecular adaptor, ZSL, is identified that links transverse filaments ZYP1 to central element SCEP1/2 to drive synaptonemal complex assembly in Brassica napus. Loss of ZSL abolishes synaptonemal complex formation, disrupts meiotic chromosome segregation, and markedly increases crossovers, providing mechanistic insight into meiotic fidelity ...
Miaowei Geng, Shaochen Jia, Fei Cao, Cuiping Liu, Heshuang Zhang, Gang Xu, Jixin Zhuang, Yashi Zhang, Can Liu, Yuhang Zhao, Zilin Guo, Xinjie Yuan, Jiaqing Yang, Lei Chu, Bowei Cai, Hu Zhao, Chao Yang   +16 more
wiley   +1 more source

Mononuclear cell transcriptome changes associated with dimethyl fumarate in MS. [PDF]

, 2018
ObjectiveTo identify short-term changes in gene expression in peripheral blood mononuclear cells (PBMCs) associated with treatment response to dimethyl fumarate (DMF, Tecfidera) in patients with relapsing-remitting MS (RRMS).MethodsBlood samples were ...
Baranzini, Sergio E, Cencioni, Maria T, Gafson, Arie R, Kim, Kicheol, Matthews, Paul M, Nicholas, Richard, van Hecke, Wim   +6 more
core  

A Portable Fluorometer for the Detection of Glyphosate

Biosensors
Glyphosate is the most widely used herbicide worldwide, but many current detection methods rely on lab-based chromatography, requiring costly equipment and expert users.
Nathanael B. Smith, Adrian S. Rizk, Owen K. Rizk, Shahir S. Rizk   +3 more
doaj   +1 more source

Cryoablation Activates the cGAS–STING‐CXCL10 Axis in Macrophages to Enhance Anti‐Tumor Immunity in NSCLC

Advanced Science, EarlyView.
Tumor dsDNA released by cryoablation is taken up by macrophages, activating the cGAS‐STING signaling pathway. This leads to an expansion of the CXCL10+ macrophage pool and increased secretion of CXCL10, which in turn recruits CXCR3+ T cells from draining lymph nodes into the tumor microenvironment to exert anti‐tumor effects.
Xinxin Zhi, Zhengcao Xing, Libo Luo, Jiale Wang, Xinyu Liu, Jia Yu, Jizhong Yin, Bin Chen, Yiwei Liu, Hui Sun, Guanghui Gao, Lei Wang, Xiaoxia Chen, Fei Li, Hu Ma, Lin Wang, Shuo Yang, Shengxiang Ren   +17 more
wiley   +1 more source

Improved precision in aerial application equipment [PDF]

There are no author-identified significant results in this ...
Roth, L. O.
core   +1 more source

Development of a pathogenicity testing system for Dothistroma pini infection of Pinus radiata : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Microbiology at Massey University [PDF]

, 2004
Dothistroma pini is a fungal pathogen of pine species around the world and can be found in most parts of New Zealand. Infection by D. pini causes a disease commonly known as Dothistroma needle blight. Dothistroma needle blight has a significant financial
West, Phillip John
core  

A Comparison of the Pac-X Trans-Pacific Wave Glider Data and Satellite Data (MODIS, Aquarius, TRMM and VIIRS) [PDF]

, 2014
Tracy A. Villareal, Marine Science Institute and Department of Marine Science, The University of Texas at Austin, Port Aransas, Texas, United States of AmericaCara Wilson, Environmental Research Division, Southwest Fisheries Science Center, National ...
Villareal, Tracy A., Wilson, Cara
core   +3 more sources