Results 111 to 120 of about 129,172 (353)

SETD1A Regulates Glycolysis and Senescence of Nucleus Pulposus Cells via H3K4me3–HELZ2/PPARα‐HIF1α Axis to Drive Intervertebral Disc Degeneration

Advanced Science, EarlyView.
SETD1A is a key epigenetic regulator in NPCs during IDD. In normal NPCs, it sustains H3K4me3–HELZ2/PPARα–HIF1α signaling to maintain glycolytic energy metabolism and proliferation. In degenerated NPCs, reduced SETD1A disrupts this axis, impairing glycolysis and accelerating senescence, highlighting a promising therapeutic target for IDD.
Jiawei Fu, Xue Leng, Jiang Long, Zhengao Liao, Xiaoqin An, Xuezheng Ai, Dan Long, Changqing Li, Bo Huang, Yue Zhou, Shiwu Dong, Chencheng Feng   +11 more
wiley   +1 more source

Profil Densitas Akustik Perikanan di Perairan Lamalera, Nusa Tenggara Timur (Fisheries Acoustics Density Profiles in Lamalera Waters, East Nusa Tenggara)

Ilmu Kelautan, 2013
Sound Scattering Layer merupakan lapisan sejumlah organisme yang memantulkan sinyal hidroakustik. Pengetahun mengenai hal ini penting untuk memahami fungsi ekosistem epipelagis. Penelitian ini bertujuan untuk mendapatkan kuantitas akustik guna memperoleh
Adi Purwandana, Fis Purwongko
doaj   +1 more source

Cotton Recruits Soil‐Derived Delftia tsuruhatensis to Suppress Aphid Detoxification Via Salicylic Acid‐Mediated Defense

Advanced Science, EarlyView.
This study systematically reveals a complex interactive network involving plants, microbes, and insects, elucidating the ecological and molecular mechanisms by which cotton enhances its resistance to aphids through the active recruitment of the beneficial soil bacterium Delftia tsuruhatensis.
Hui Xue, Fengchao Diao, Qiqing Yu, Xiangzhen Zhu, Tingfang Zhong, Li Wang, Kaixin Zhang, Dongyang Li, Jichao Ji, Junyu Luo, Jinjie Cui, Xueke Gao   +11 more
wiley   +1 more source

A Biomimetic Nanoparticle System Intercepts and Degrades Thrombospondin‐1 to Restore Vascular Homeostasis After Ischemic Injury

Advanced Science, EarlyView.
TAX2‐NPs capture extracellular TSP‐1 in the injured liver and promote its macrophage‐mediated autophagic degradation. This process blocks TSP‐1/CD47 signaling, restores VEGFR2‐AKT activity, preserves endothelial function, and mitigates hepatic ischemia‐reperfusion injury.
Haorui Wang, Xiandi Meng, Yanbao Xin, Kuirong Mao, Huizhu Tan, Changkai Ma, Xiuxiu Cong, Mengfei Zhao, Meiling Yu, Si Chen, Yue Hou, Yong‐Guang Yang, Tianmeng Sun   +12 more
wiley   +1 more source

A Combined Spectrophotometer and Fluorometer to Demonstrate the Principles of Absorption Spectroscopy

Journal of Chemical Education, 2021
A. Lietard, Martin A. Screen, Diana L. Flindt, Caleb J. C. Jordan, Jacquie Robson, J. Verlet   +5 more
semanticscholar   +1 more source

Assessment of wavelength-dependent parameters of photosynthetic electron transport with a new type of multi-color PAM chlorophyll fluorometer

Photosynthesis Research, 2012
Technical features of a novel multi-color pulse amplitude modulation (PAM) chlorophyll fluorometer as well as the applied methodology and some typical examples of its practical application with suspensions of Chlorella vulgaris and Synechocystis PCC 6803
U. Schreiber, C. Klughammer, J. Kolbowski   +2 more
semanticscholar   +1 more source

Detection of Borrelia burgdorferi in historic tick samples and its relevance to the white-tailed deer population in New Hampshire [PDF]

, 2018
The cases of Lyme disease in New Hampshire have increased over time. There are speculations that increasing number of Lyme disease cases in New Hampshire are due to environmental factors, such as warmer climate, white-footed mouse population, white ...
Rakasiwi, Tasya
core   +1 more source

Engineered Carbon Dots from a Traditional Herb Pair Orchestrate Concurrent Antioxidant and AP‐1‐Mediated Inflammation to Attenuate Renal Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study integrates two complementary traditional Chinese medicine components as precursors to synthesize bioactive AM‐AS@CDs. Compared with single‐component CDs, these dual‐component CDs exhibit enhanced antioxidant capacity and superior renoprotective effects.
Bixiao Liu, Fuying Zhu, Zhuqing Wang, Jiawen Chen, Xiaomiao Cui, Congzhong Yang, Yao Peng, Dengyuan Feng, Li Lu, Hui Wei, Xiaozhi Zhao   +10 more
wiley   +1 more source

RRS Discovery Cruise DY017, 20 Oct - 05 Nov 2014. Outer Hebrides process cruise [PDF]

, 2015
The continental shelf region immediately west of the UK and North of Ireland is thought to be a key region for the exchange of nutrients, carbon and water between the NW European continental shelf and the open North Atlantic Ocean yet it remains ...
et al,, Painter, S.C.
core  

Stage‐Specific H3K14 and H3K23 Succinylation Orchestrates Insect Metamorphosis and Oogenesis

Advanced Science, EarlyView.
Stage‐specific succinylation of histone H3 at lysine 14 and 23 differentially controls insect metamorphosis and oogenesis through distinct GPCR‐PKC signaling cascades, revealing an evolutionarily conserved epigenetic mechanism that coordinates key life‐history traits.
Yu‐Pu Jing, Lunjie Li, Libin Yang, Lin‐Jie Zhang, Qiang Yan, Ci Zhang, Zanrong Wen, Guangze Yu, Qian Li, Shutang Zhou   +9 more
wiley   +1 more source