Results 121 to 130 of about 129,172 (353)
ABSTRACT Introduction Chronic rhinosinusitis (CRS) is an inflammatory disease with many different contributing factors, including bacterial infection. CRS patients are typically managed with medical therapies; however, these treatments frequently fail, leaving surgery as the only viable option.
Sintayehu Ambachew +8 more
wiley +1 more source
Satellite detection of phytoplankton export from the mid-Atlantic Bight during the 1979 spring bloom [PDF]
Analysis of Coastal Zone Color Scanner (CZCS) imagery confirms shipboard and in situ moored fluorometer observations of resuspension of near-bottom chlorophyll within surface waters (1 to 10 m) by northwesterly wind events in the mid-Atlantic Bight.
Dieterle, D. A. +2 more
core +1 more source
Ciglitazone-a human PPARγ agonist-disrupts dorsoventral patterning in zebrafish. [PDF]
Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated transcription factor that regulates lipid/glucose homeostasis and adipocyte differentiation.
Cheng, Vanessa +3 more
core
ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda +4 more
wiley +1 more source
Migration of Net Phytoplankton and Zooplankton in Mendum’s Pond, New Hampshire [PDF]
The study examines the vertical distribution and migratory behavior of net phytoplankton and zooplankton of Mendum’s Pond in Barrington, N.H. The cyanobacteria, Microcystis and Aphanocapsa were the dominant net phytoplankton in this lake.
Murby, Amanda L.
core +1 more source
Using a 3D cell culture model of the fibrotic barrier in pancreatic cancer, this work shows that inhibiting NUAK2 kinase in pancreatic stellate cells enhances macromolecular drug delivery. Mechanistically, NUAK2 inhibition disrupted actin stress fiber assembly to downregulate collagen I expression, thus enhancing macromolecular permeability.
Misaki Nakamura +14 more
wiley +1 more source
A High-Performance and Versatile Fluorometer for Chlorophyll a Monitoring
Chlorophyll a (Chl a) monitoring is vital for aquatic ecosystem assessment but is challenged by low signals and interference. Addressing this, we introduced balanced maximum entropy m-sequence modulation for Chl a fluorescence detection, developing a ...
Tingkai Zhang +3 more
doaj +1 more source
Redox responsive mesoporous silica nanoparticles (MSNs) were engineered to deliver gemcitabine (Gem) and cisplatin (cisPt) at defined ratios to overcome chemoresistance in pancreatic ductal adenocarcinoma (PDAC). Optimized Gem MSNs and Gem cisPt MSNs enhanced cytotoxicity in murine and human Gem resistant models, with select formulations inducing ...
Tamanna Binte Huq +5 more
wiley +1 more source
Automated in situ observations of upper ocean biogeochemistry, bio-optics, and physics and their potential use for global studies [PDF]
The processes controlling the flux of carbon in the upper ocean have dynamic ranges in space and time of at least nine orders of magnitude. These processes depend on a broad suite of inter-related biogeochemical, bio-optical, and physical variables ...
Dickey, Tommy D. +2 more
core +1 more source
Experimental Evidence for a Metal‐Related Function of a Cyanobactin
Cyanobactins such as patellamides are produced by cyanobacteria profusely and have been studied extensively, but almost exclusively for their cytotoxic properties. Discussed is unprecedented experimental evidence for a metal‐related biological function – likely CO2 transport from the ascidian to the cyanobacterial symbiont.
Philipp Baur +8 more
wiley +1 more source

