Results 81 to 90 of about 122,840 (290)
Advanced Science, EarlyView.We developed a macrophage‐based therapeutic platform, termed trackable tolerogenic macrophages (TTM), for dual‐function immunomodulation and visualization in vivo. TTM cells were engineered to overexpress PD‐L1, incorporate bioorthogonal cell surface tags, and load rapamycin for sustained release.
Yihui Wang +14 more
wiley +1 more source
A field-deployable and handheld fluorometer for environmental water quality monitoring
Micro and Nano Systems Letters, 2018 This work reports the development of a field-deployable and fully handheld fluorometer for environmental water monitoring. Our developed fluorimeter can detect both green algae and cyanobacteria (blue-green algae) while simultaneously differentiating and
Young-Ho Shin +2 more
doaj +1 more source
Maize open-pollinated populations physiological improvement: validating tools for drought response participatory selection [PDF]
, 2019 Participatory selection—exploiting specific adaptation traits to target environments—helps to guarantees yield stability in a changing climate, in particular under low-input or organic production.
Araus +25 more
core +2 more sources
Advanced Science, EarlyView.This study identifies mutation‐intolerant genes (MIGs), which are mutationally constrained in tumors despite normal‐tissue variability. Using miDriver, the authors pinpoint MIGs essential for tumor‐intrinsic fitness and immune evasion. Focusing on CHEK1, they show it drives tumor fitness and sculpts an immunosuppressive niche via the MIF–CD74 axis ...
Tao Wang +16 more
wiley +1 more source
Advanced ScienceHere, a separation‐free and label‐free portable aptasensor is developed for rapid and sensitive analysis of tumor‐derived exosomes (TEXs). It integrated a parallel rolling circle amplification (RCA) reaction, selective binding of metal ions or small ...
Yaqin He +5 more
doaj +1 more source
New approaches to the measurement of chlorophyll, related pigments and productivity in the sea [PDF]
In the 1984 SBIR Call for Proposals, NASA solicited new methods to measure primary production and chlorophyll in the ocean. Biospherical Instruments Inc. responded to this call with a proposal first to study a variety of approaches to this problem.
Booth, C. R., Keifer, D. A.
core +1 more source
Shipboard Techniques for Oceanographic Observations [PDF]
, 1995 This report gives the details of water sampling methods and chemical analyses used during MLML participation in the EOS MODIS investigations. It is intended to be used as a reference manual for those engaged in shipboard work.
Broenkow, William W. +3 more
core
Advanced Science, EarlyView.A central molecular adaptor, ZSL, is identified that links transverse filaments ZYP1 to central element SCEP1/2 to drive synaptonemal complex assembly in Brassica napus. Loss of ZSL abolishes synaptonemal complex formation, disrupts meiotic chromosome segregation, and markedly increases crossovers, providing mechanistic insight into meiotic fidelity ...
Miaowei Geng +16 more
wiley +1 more source
Development of a Cone Penetrometer for Measuring Spectral Characteristics of Soils in Situ [PDF]
, 1993 A patent was recently granted to the U.S. Army for an adaptation of a soil cone penetrometer that can be used to measure the spectral characteristics (fluorescence or reflectance) of soils adjacent to the penetrometer rod. The system can use a variety of
Lee, Landris T., Jr., Malone, Philip G.
core +1 more source
A next-generation sequencing approach to identify gene mutations in early-and late-onset hypertrophic cardiomyopathy patients of an Italian cohort [PDF]
, 2016 Sequencing of sarcomere protein genes in patients fulfilling the clinical diagnostic criteria for hypertrophic cardiomyopathy (HCM) identifies a disease-causing mutation in 35% to 60% of cases.
Autore, Camillo +11 more
core +1 more source