Fluoroquinolone-Induced Metabolic Dysregulation and Oxidative Stress Orchestrate Bacterial Demise. [PDF]
Zhou C +10 more
europepmc +1 more source
Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods
Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Burcu Karayavuz +1 more
wiley +1 more source
Fluoroquinolone prescribing to older adults following FDA boxed warnings: a comparative analysis. [PDF]
Jia M +4 more
europepmc +1 more source
Carbon quantum dots engineered through heteroatom doping and surface functionalization enable selective tetracycline sensing via fluorescence modulation. Integration of machine learning with portable sensing platforms enhances discrimination accuracy, matrix tolerance, and real‐world applicability for intelligent antibiotic monitoring in food and ...
Mohamed Abu Shuheil +8 more
wiley +1 more source
Fluoroquinolones for TB preventive treatment of contacts exposed to persons with multidrug-resistant TB: a systematic review and meta-analysis. [PDF]
Sidhu H +6 more
europepmc +1 more source
Trends in Enterobacteriaceae Resistance Patterns: A Nine‐Year Retrospective Study From North Lebanon
ABSTRACT Background and Aims Antimicrobial resistance (AMR) in Enterobacteriaceae poses a critical threat to global health, particularly in regions where antibiotic misuse and limited surveillance prevail. Intensive care units (ICUs) act as focal points for resistance emergence and dissemination. This study aimed to evaluate long‐term resistance trends
Mazen Zaylaa +12 more
wiley +1 more source
Fluoroquinolone Prophylaxis Uncovers High Prevalence Rates of Fluoroquinolone-Resistant <i>Enterobacterales</i> Colonization in Multiple Myeloma Autologous Transplant Patients: A Prospective Cohort Study. [PDF]
Patel C +12 more
europepmc +1 more source
ABSTRACT Background and Aims Typhoid fever remains a significant public health concern in Bangladesh due to overcrowding, insufficient sanitation, unsafe food and contaminated water exposure, and antimicrobial resistance. The aim of this research is to gather evidence‐based information to guide future public health programs and educational initiatives ...
Most. Nazma Parvin +2 more
wiley +1 more source
Prevalence and Risk Factors of Fluoroquinolone Resistance in Major Bacterial Pathogens: A Systematic Review and Meta-Analysis. [PDF]
Anggriawan IMB, Rochmawati ID.
europepmc +1 more source
Topoisomerase Inhibitors: Fluoroquinolone Mechanisms of Action and Resistance.
D. Hooper, G. Jacoby
semanticscholar +1 more source

