Results 141 to 150 of about 94,119 (260)

Successful Management of Septic Splenitis in an Abyssinian Cat

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
A 3.5‐year‐old female neutered Abyssinian with pyrexia of unknown origin and splenomegaly was diagnosed with septic splenitis. Complete resolution of clinical signs followed splenectomy and antibiotic treatment with pradofloxacin. Septic splenitis, although uncommon, should be considered as a differential diagnosis in patients with splenomegaly and ...
Martina Vecín Sancho, Perrine Henry, Mica Taylor, Catherine Davidson, María Lázaro Muñoz, Efa Llewellyn, Maša Vilfan, Paola Cazzini, Linda Morrison, Kelly Blacklock, Danièlle Gunn‐Moore   +10 more
wiley   +1 more source

Glanders: Past, Present and Future of a Neglected Zoonosis as a Threat in Veterinary and Human Health

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This review displays a comprehensive overview of glanders, including aetiology, epidemiology, pathogenesis, diagnosis, control strategies and ongoing eradication programs. It has also reviewed differential diagnosis and treatment both in animals and humans as well as organism's antimicrobial properties.
Yahya Kanani, Ahmad Oryan, Abdollah Derakhshandeh   +2 more
wiley   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, Volume 183, Issue 9, Page 1779-1813, May 2026.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

Advancing Pharmacoequity in Low‐ and Middle‐Income Countries via Model Informed Drug Development

Clinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT Across low‐ and middle‐income countries (LMICs) inequities in access to safe, effective medicines persist due to limited regulatory capacity, inadequate financing, and insufficient local data. Regulatory authorities are engaging with model‐informed drug development (MIDD), but uneven technical readiness and resource gaps limit uptake ...
Henry Enzama, Francis Williams Ojara, Ian S. Haworth, Sandra Cvijic, Catriona Waitt, Thaddeus H. Grasela   +5 more
wiley   +1 more source

Postoperative Antibiotics Do Not Prevent Surgical Site Infections After Routine Ophthalmic Soft Tissue Surgeries in Dogs—A Retrospective Study

Veterinary Ophthalmology, Volume 29, Issue 3, May 2026.
ABSTRACT Purpose To compare the incidence of surgical site infections (SSI) following routine ophthalmic soft tissue surgeries in dogs receiving (AB) and not receiving (noAB) postoperative antibiotics. Methods Clinical records of dogs that underwent enucleations, wedge resections, medial canthoplasties, and simple and complicated eyelid surgeries with ...
Ana Cristina Piroth, Claudia Busse
wiley   +1 more source

Treatment Approaches for Refractory <i>Mycoplasma genitalium</i> Infection. [PDF]

Open Forum Infect Dis
Tenney R, Portillo ER, Bacic Lima D, Torres Isasiga JA.   +3 more
europepmc   +1 more source

Comparison of Infectious Complications After Transrectal Prostate Biopsy Under Two Antibiotic Prophylaxis Regimens: Ceftriaxone Plus Cefixime Versus Ciprofloxacin Plus Gentamicin. [PDF]

Int J Urol
ABSTRACT Objectives To compare the effectiveness and safety of two antibiotic prophylaxis regimens, ciprofloxacin plus gentamicin and ceftriaxone plus cefixime, in preventing infectious complications after transrectal ultrasound‐guided prostate biopsy.
Balık AY, Ediz E, Ayvacık B, Taşkıran AT, Başaran E, Baba D.   +5 more
europepmc   +2 more sources

Allium‐Derived Compounds Against Multidrug‐Resistant Bacteria: Antibacterial Activity and Synergistic Effects

ChemMedChem, Volume 21, Issue 8, 28 April 2026.
This study evaluates four compounds derived from the genus Allium against 330 multidrug‐resistant bacteria. Propyl‐propane‐thiosulfonate (PTSO) exhibits the highest activity, particularly against Gram‐positive strains, while Gram‐negative bacteria are less affected.
Antonio Sorlózano‐Puerto, Yariel Figueroa‐Vega, Pablo Martín‐Valenzuela, José Manuel de la Torre‐Ramírez, Alberto Baños, José Gutiérrez‐Fernández   +5 more
wiley   +1 more source

A new therapeutic strategy for spotted fever group rickettsioses: a proposal for evaluating combination therapy with tetracycline and fluoroquinolones. [PDF]

Front Cell Infect Microbiol
Itoh K, Tsutani H, Mitsuke Y, Ikawa M, Iwasaki H.   +4 more
europepmc   +1 more source

Synthesis of an Enzyme‐Triggered Chitosan‐Based Drug Delivery System for Peri‐Implantitis Prevention

Chemistry – A European Journal, Volume 32, Issue 16, 25 April 2026.
ABSTRACT Dental implants have become a leading solution for tooth loss, yet bacterial infections remain a major complication. Antibacterial implant coatings are an important approach to reduce or prevent bacterial infections at the implant. Given the oral cavity's complex microbiome and the importance of some commensal bacteria, it is crucial to ...
Nelly Senze Nnane, Amit Gaikwad, Muhammad Imran Rahim, Andreas Winkel, Oliver Hergert, Till Beuerle, Meike Stiesch, Henning Menzel   +7 more
wiley   +1 more source