Results 101 to 110 of about 5,793,605 (328)

Topical Fluoroquinolones: Current Perspectives

Delhi Journal of Ophthalmology, 2015
Fluoroquinolone class of antibiotics has become popular by the virtue of its properties like broad spectrum bactericidal activity, better intraocular concentration, minimal side effects and resistance.
Sayali Pradhan, N Venkatesh Prajna
doaj   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Antibiotic resistance in the environment, with particular reference to MRSA [PDF]

, 2008
The introduction of β-lactam antibiotics (penicillins and cephalosporins) in the 1940s and 1950s probably represents the most dramatic event in the battle against infection in human medicine.
William Gaze, Gaze, William H., Hawkey, Peter, Peter Hawkey, Hawkey, P. M., O'Neill, Colette, O'Neill, C, Colette O'Neill, Elizabeth Wellington, Gaze, W, Wellington, E, Wellington, Elizabeth, Wellington, E. M. H., Gaze, William   +13 more
core   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Genomic Characterization of a Fluoroquinolone Intermediate Resistance Herbaspirillum sp. Strain HhutSZ1 Rarely Causing Bacteremia [PDF]

Yi Luo,1 Taihan Li,1 Suo Zhang,2 Dayong Gu,1 Bing Fan1 1Department of Laboratory, Shenzhen Second People’s Hospital, Shenzhen, People’s Republic of China; 2Department of Rheumatology and Immunology, Shenzhen Second People’s Hospital, Shenzhen, People’s ...
Gu D, Li T, Luo Y, Zhang S, Fan B
core  

Fluoroquinolone Resistance and Clostridium difficile, Germany [PDF]

, 2010
We characterized 670 Clostridium diffi cile isolates collected from patients in 84 hospitals in Germany in 2008. PCR ribotyping showed high prevalence of ribotype 001 and restricted dissemination of ribotype 027 strains.
Nübel, Ulrich, Wolfgang Witte, Witte, Wolfgang, Ulrich Nübel, Zaiß, Henning, Nils Henning Zaiß   +5 more
core   +1 more source

Mechanistic insights into HipA‐mediated bacterial persistence: Role of initial cellular states and toxin expression kinetics

mLife, EarlyView.
Abstract Persistent bacteria subpopulations showing multidrug tolerance pose significant challenges to antibiotic therapy. While the HipBA toxin–antitoxin (TA) system is known to play a role in persister formation, existing studies predominantly focus on its kinase activity and intracellular regulatory pathways, with limited attention to the ...
Jing Zhao, Yixiao Xiong, Hongxia Zhao, Jin Wang, Xiaona Fang   +4 more
wiley   +1 more source

Fluoroquinolone resistance and phylogenetic analysis of broiler Campylobacter jejuni isolates in Indonesia [PDF]

, 2023
Consumption of poultry contaminated with Campylobacter jejuni is the main source of sporadic campylobacteriosis in humans, while fluoroquinolone resistance is increasing in Campylobacter jejuni isolated from poultry.
Khairullah, Aswin R., Moses, Ikechukwu B., Effendi, Mustofa H., Silaen, Otto S.M., Yanestria, Sheila M., Hasib, Abdullah, Mariyono, Mariyono, Tyasningsih, Wiwiek, Samodra, Muhammad E.E., Ikaratri, Rosmita, Kurniawan, Shendy C., Dameanti, Fidi N.A.E.P.   +11 more
core   +1 more source

Frequency and Geographic Distribution of gyrA and gyrB Mutations Associated with Fluoroquinolone Resistance in Clinical Mycobacterium Tuberculosis Isolates: A Systematic Review

PLoS ONE, 2015
Background The detection of mutations in the gyrA and gyrB genes in the Mycobacterium tuberculosis genome that have been demonstrated to confer phenotypic resistance to fluoroquinolones is the most promising technology for rapid diagnosis of ...
E. Avalos, D. Catanzaro, A. Catanzaro, T. Ganiats, S. Brodine, John E. Alcaraz, T. Rodwell   +6 more
semanticscholar   +1 more source

ISAba1‐mediated crp‐osmC amplification enhances host‐associated fitness in Acinetobacter baumannii

mLife, EarlyView.
Abstract Acinetobacter baumannii is a pathogen, highly adaptable to both hospital‐ and host‐associated environments. Understanding the genetic mechanisms underlying its adaptability is critical for controlling its persistence. Our study identified the crp‐osmC gene cluster, flanked by ISAba1 elements, as a significant genetic structure undergoing ...
Da‐Wei Wei, Jiangqing Huang, Hailing Fang, Xinyu Wang, Gang Zhang, Chao Wang, Yuqin Song, Jie Feng   +7 more
wiley   +1 more source