Results 101 to 110 of about 55,766 (252)

In vitro selection of fluoroquinolone resistance in Brucella melitensis [PDF]

open access: yes, 2009
International audienceMoxifloxacin-resistant mutants of 16M [moxifloxacin minimum inhibitory concentration (MIC)=1mg/L] were selected in order to characterise fluoroquinolone resistance mechanisms in this species. Eight independent mutants were obtained,
Ravanel, N., Gestin, B., Maurin, M.
core   +1 more source

Delafloxacin suppresses DEPDC1 expression and induces G2/M arrest in non‐small cell lung cancer cells: A drug repurposing study

open access: yesSmart Molecules, EarlyView.
This study presents Delafloxacin repurposed as a DEPDC1‐targeting therapeutic aiming to suppress lung cancer progression. It highlights a novel strategy for lung cancer treatment with potential clinical applications. Abstract Emerging evidence highlights the oncogenic role of the Dishevelled, Egl‐10, and Pleckstrin domains containing 1 (DEPDC1) gene in
Noman Ali   +4 more
wiley   +1 more source

Trends in South Korean antimicrobial use and association with changes in Escherichia coli resistance rates: 12-year ecological study using a nationwide surveillance and antimicrobial prescription database.

open access: yesPLoS ONE, 2018
The purpose of this study is to determine the correlation between use of antimicrobials, such as fluoroquinolone, cefoxitin, and cefotaxime, and Escherichia coli resistance using a nationwide database.
Young Ah Kim   +4 more
doaj   +1 more source

Fluoroquinolone-Resistant Escherichia coli Infections after Transrectal Biopsy of the Prostate in the Veterans Affairs Healthcare System

open access: yesPathogens and Immunity, 2016
Background: Recent reports suggest that infections due to fluoroquinolone-resistant Escherichia coli (E. coli) are an increasingly common complication of transrectal biopsy of the prostate (TBP) in the United States.
Elie Antoun Saade   +4 more
doaj   +1 more source

Antibiotic resistance in the environment, with particular reference to MRSA [PDF]

open access: yes, 2008
The introduction of β-lactam antibiotics (penicillins and cephalosporins) in the 1940s and 1950s probably represents the most dramatic event in the battle against infection in human medicine.
William Gaze   +13 more
core   +1 more source

‘Knowledge, attitudes and practices’ survey of Austrian veterinarians' antibiotic use in clinical practice

open access: yesVeterinary Record, EarlyView.
Abstract Background Antimicrobial resistance (AMR) is a critical global health issue, with antimicrobial use (AMU) in veterinary medicine playing a relevant role in its emergence. This study aimed to evaluate the knowledge, attitudes and practices of Austrian veterinarians regarding AMU and AMR.
Clair L. Firth   +4 more
wiley   +1 more source

Topical Fluoroquinolones: Current Perspectives

open access: yesDelhi Journal of Ophthalmology, 2015
Fluoroquinolone class of antibiotics has become popular by the virtue of its properties like broad spectrum bactericidal activity, better intraocular concentration, minimal side effects and resistance.
Sayali Pradhan, N Venkatesh Prajna
doaj   +1 more source

Genomic Characterization of a Fluoroquinolone Intermediate Resistance Herbaspirillum sp. Strain HhutSZ1 Rarely Causing Bacteremia [PDF]

open access: yes
Yi Luo,1 Taihan Li,1 Suo Zhang,2 Dayong Gu,1 Bing Fan1 1Department of Laboratory, Shenzhen Second People’s Hospital, Shenzhen, People’s Republic of China; 2Department of Rheumatology and Immunology, Shenzhen Second People’s Hospital, Shenzhen, People’s ...
Gu D, Li T, Luo Y, Zhang S, Fan B
core   +1 more source

Fluoroquinolone Resistance and Clostridium difficile, Germany [PDF]

open access: yes, 2010
We characterized 670 Clostridium diffi cile isolates collected from patients in 84 hospitals in Germany in 2008. PCR ribotyping showed high prevalence of ribotype 001 and restricted dissemination of ribotype 027 strains.
Nübel, Ulrich   +5 more
core   +1 more source

Reusing health records from farm animal practices at scale: A potential complementary method of surveillance

open access: yesVeterinary Record, EarlyView.
Abstract Background Disease in primary care frequently represents a surveillance blind spot, particularly for diseases affecting farm animals. Methods Electronic health records (EHRs) were collected from four farm animal veterinary practices in Wales (February 2024‒January 2025) as part of a pilot study.
Beverley Hopkins   +8 more
wiley   +1 more source

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