Results 201 to 210 of about 5,793,605 (328)

Pragmatic Phenotype–Electrophysiology–Genomics Integration in Pediatric Congenital Myasthenic Syndromes: Insights From 36 Patients in a Single‐Center Study in China

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
In 36 Chinese pediatric CMS patients, integrated phenotype, RNS, and genomic assessment revealed marked genetic heterogeneity across 17 CMS‐associated genes and frequent VUS‐related uncertainty. Genotype‐informed therapy improved MG‐ADL scores, while CHAT‐CMS identified a high‐risk subgroup for early respiratory failure and mortality.
Liya Cui, Kaiyue Ma, Xiaona Fu, Lin Ge, Bingbing Jia, Wenna Ma, Lei Yang, Zhimei Liu, Junlan Lv, Wenmiao Xu, Lijuan Wang, Guangyuan Zhao, Jiuwei Li, Jie Wu, Quan Wang, Changhong Ding, Xiaotun Ren, Xinming Shen, Hui Xiong   +18 more
wiley   +1 more source

Antimicrobial Susceptibility and Fluoroquinolone Resistance Patterns of <i>Pseudomonas aeruginosa</i> Isolated from Canine Otitis Externa in Romania. [PDF]

Antibiotics (Basel)
Popa I, Iancu I, Iorgoni V, Gligor A, Imre K, Tîrziu E, Bochiș T, Pop C, Degi J, Ivan A, Dahma M, Plotuna AM, Orghici G, Herman V, Nichita I.   +14 more
europepmc   +1 more source

Gyrase Mutations Are Associated with Variable Levels of Fluoroquinolone Resistance in Mycobacterium tuberculosis

Journal of Clinical Microbiology, 2016
M. Farhat, K. Jacobson, M. Franke, D. Kaur, A. Sloutsky, C. Mitnick, M. Murray   +6 more
semanticscholar   +1 more source

Venetoclax for elderly patients with acute myeloid leukaemia unfit for intensive chemotherapy: Prospects, resistance mechanisms and management strategies

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Resistance to venetoclax has become a critical bottleneck limiting its long‐term clinical benefits. A thorough understanding of the underlying resistance mechanisms and the development of novel strategies to overcome resistance are central to improving survival outcomes in elderly AML patients. Abstract To date, the treatment of acute myeloid leukaemia
Jinlin Zhang, Jile Liu, Mohan Zhao, Xiaoyu Zhang, Linlin Liu, Mengnan Li, Changze Cao, Rui Zhang, Mingfeng Zhao   +8 more
wiley   +1 more source

A first look into the genomic characterization and fluoroquinolone resistance genotypes of Mycoplasma spp. in Colombian poultry. [PDF]

Poult Sci
Forero-Marin S, Gomez AP, Beltran-Leon M, Ramirez-Nieto G.   +3 more
europepmc   +1 more source

Tuberculosis in Sudan: A Comprehensive Narrative Review of Epidemiological Trends, Diagnosis, Drug Resistance, Challenges, and Data Gaps

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims This narrative review aims to provide a comprehensive overview of tuberculosis (TB) in Sudan, focusing on prevalence, drug resistance patterns, and associated challenges while identifying knowledge gaps in scientific research and data needed for effective management.
Mohammad Azhar Kamal, Hisham N. Altayb, Shima M. Abdulgader, Ehssan Moglad   +3 more
wiley   +1 more source

Laboratory‐Detected Clostridioides difficile Stool‐Test Positivity and Mortality in Sepsis: A Retrospective Cohort Study

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Sepsis disrupts intestinal microbiota, and broad‐spectrum antibiotics may worsen dysbiosis. Clostridioides difficile (C. difficile) infection (CDI) is a prevalent nosocomial enteric pathogen among critically ill patients, yet its prognostic implications in sepsis remain inadequately studied.
Jiyun Hu, Fuxing Deng, Tingyue Hu, Binbin Meng, Songyun Deng, Lina Zhang, Wenchao Li   +6 more
wiley   +1 more source

Phenotype-First Diagnostic Framework for Tracking Fluoroquinolone Resistance in <i>Escherichia coli</i>. [PDF]

Diagnostics (Basel)
Marzouk E, Almuzaini AM.
europepmc   +1 more source

Prediction of Fluoroquinolone Resistance in Gram-Negative Bacteria Causing Bloodstream Infections

Antimicrobial Agents and Chemotherapy, 2016
Seejil Dan, Ansal Shah, J. Justo, P. Bookstaver, J. Kohn, H. Albrecht, M. Al-Hasan   +6 more
semanticscholar   +1 more source

Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention

iMetaOmics, Volume 3, Issue 3, September 2026.
The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie, Jingyuan Ye, Sheng Wang, Maoyun Liu, Fengsheng Dai, Mingzhen Bai, Yi Wang, Athena Savoji, Yu Wang, Phillip B. Hylemon, Huiping Zhou, Hui Li, Dewei Li   +12 more
wiley   +1 more source