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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background Fluoroquinolones are first‐line antibiotics recommended for the treatment of complicated urinary tract infections (UTIs), with frequent reports of adverse effects of aortic aneurysm (AA) and aortic dissection (AD).
Yin‐Yang Chen +6 more
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Fluoroquinolones’ Biological Activities against Laboratory Microbes and Cancer Cell Lines
Molecules, 2022 Development of novel derivatives to rein in and fight bacteria have never been more demanding, as microbial resistance strains are alarmingly increasing.
Ghadeer A. R. Y. Suaifan +2 more
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Frontiers in Veterinary Science, 2022 Mycoplasma bovis (M. bovis) is one of the important pathogens for yaks. Aminoglycosides and fluoroquinolones are frequently used medications for the treatment of M. bovis. Drug-resistant strains were inevitable with the abuse of antibiotics.
Jiaqiang Niu +5 more
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Cardiotoxicity of fluoroquinolones [PDF]
Journal of Antimicrobial Chemotherapy, 2002 Currently marketed fluoroquinolones enjoy an admirable safety profile that is not matched by any other antibiotic group. The widespread use of fluoroquinolones in the elderly, who are susceptible to cardiac arrhythmias because of underlying heart diseases, metabolic derangement and use of anti-arrhythmic agents and other medications that prolong the QT
Ethan Rubinstein, John Camm
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Transporter and metabolizer gene polymorphisms affect fluoroquinolone pharmacokinetic parameters
Frontiers in Pharmacology, 2022 Tuberculosis (TB) is an infectious disease that occurs globally. Treatment of TB has been hindered by problems with multidrug-resistant strains (MDR-TB). Fluoroquinolones are one of the main drugs used for the treatment of MDR-TB.
Nurul Annisa +5 more
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Pharmacodynamics of Fluoroquinolones [PDF]
Clinical Infectious Diseases, 1998 Fluoroquinolone antimicrobial agents are highly active against aerobic or facultative gram-negative bacilli. The fluoroquinolones have been shown to be very concentration dependent in their rates of killing and also have a postantibiotic effect against most gram-negative pathogens.
Klaus Borner, Peter Koeppe, Hartmut Lode
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BMC Pediatrics, 2020 Background To evaluate the safety of using fluoroquinolones in pediatric population in Taiwan. Methods Patients aged 0~18 years old with fluoroquinolones prescriptions ≥5 consecutive days during year 2000 to 2013 were selected from the National Health ...
Pei-Han Yu +6 more
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Cells, 2021 Fluoroquinolones cause phototoxic reactions, manifested as different types of skin lesions, including hyperpigmentation. The disturbances of melanogenesis indicate that fluoroquinolones may affect cellular processes in melanocytes.
Justyna Kowalska +5 more
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Systemic use of fluoroquinolone in children [PDF]
Korean Journal of Pediatrics, 2013 Fluoroquinolones are an important class of antibiotics that are widely used in adult patients because of their broad spectrum of activity, good tissue penetration, and oral bioavailability.
Soo-Han Choi +2 more
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Revista Española de Quimioterapia, 2023 Fluoroquinolones (FQs) are one of the most commonly prescribed classes of antibiotics. Although they were initially well tolerated in randomized clinical trials, subsequent epidemiological studies have reported an increased risk of threatening, severe, long-lasting, disabling and irreversible adverse effects (AEs), related to neurotoxicity and collagen
José Barberán +6 more
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