Adverse reactions in a dose-ranging study with a new long-acting fluoroquinolone, fleroxacin [PDF]
W R Bowie, V Willetts, Peter J. Jewesson
openalex +1 more source
Deuterium, a heavy isotope of hydrogen, is universal in nature, but it disrupts the mitochondrial ATPase pumps. One mechanism that biological organisms may use to reduce deuterium levels in the mitochondria is to sequester deuterium bound to carbon atoms in a small set of organic molecules that have a unique configuration to support such trapping ...
Stephanie Seneff+2 more
wiley +1 more source
EXPERIENCE OF RESPIRATORY FLUOROHINOLONUM LAEVOFLOXACINE APPLICATION («FLORACID®») IN PATIENTS WITH NON-SEVERE COMMUNITY-ACQUIRED PNEUMONIA [PDF]
The dynamics of clinical and laboratory parameters in patients with community-acquired pneumonia were studied during the treatment with respiratory fluorohinolonum laevofloxacin «Floracid®».
A.P. Rebrov+2 more
doaj
Fluoroquinolones and Risk for Methicillin-Resistant Staphylococcus aureus, Canada
Receipt of fluoroquinolones was the predominant risk factor for Clostridium difficile–associated disease (CDAD) during an epidemic in Quebec, Canada. To determine the role of antimicrobial drugs in facilitating healthcare-associated methicillin-resistant
Louiselle LeBlanc+6 more
doaj +1 more source
Embedding Pharmacogenetics Into Clinical Practice to Improve Patient Outcomes
ABSTRACT Pharmacogenomics, the use of germline genomic data to guide prescription to improve effective and safer medication, holds promise as a clinical intervention. To date in most health systems, there has been limited uptake of pharmacogenomic testing confined to a few single drug–gene associations.
John Henry McDermott+3 more
wiley +1 more source
CLINICAL USE OF MODERN FLUOROQUINOLONES IN DENTAL IMPLANTATION AND MAXILLARY SINUS LIFTING [PDF]
New fluoroquinolones like levofloxacine, with broad-spectrum of effect which is also active against anaerobic bacteria, is a prospective drug for the prevention of the inflammatory complications in implant dentistry and maxillary sinus augmentation.
S.A. Novikov+3 more
doaj
ABSTRACT Drug‐induced immune reactions are an important burden for patients and health systems. They can be classified into immediate‐drug hypersensitivity reactions (IDHRs) and delayed‐DHRs (DDHRs) based on their phenotype. Drugs do not always behave as allergens and need to bind to proteins, forming adducts.
C. Mayorga+7 more
wiley +1 more source
Substantiation of the differentiated approach to the therapy by antibiotics at an aggravation of the extented chronic periodontitis [PDF]
Investigated biochemical changes in an oral liquid of patients with the extented chronic periodontitis chronic in aggravation stage, specific features of change of activity of enzymes of a mouth at presence fluoroquinolones , in the presence of the ...
Albitskaya J.N.+4 more
doaj
Penicillin Allergy in China: Consequences of Inappropriate Skin Testing Practices and Policies
There are significant variations in practice and implementation of penicillin skin testing within China and worldwide. Indiscriminate and ‘pre‐emptive’ skin testing practices in China significantly exacerbate penicillin allergy mislabelling, and global cooperation for advancing modern penicillin allergy diagnosis is urgently needed.
Weihong Shi+5 more
wiley +1 more source
In vitro activity of T-3761, a new fluoroquinolone [PDF]
Tetsuro Muratani+2 more
openalex +1 more source