Results 71 to 80 of about 66,971 (207)

N1-Benzofused Modification of Fluoroquinolones Reduces Activity Against Gram- Negative Bacteria

, 2019
The fluoroquinolone class of antibiotics have a well-established structure-activity relationship (SAR) and a long history in the clinic, but the effect of electron-rich benzofused substituents at the N1 position remains poorly explored.
Mark, Laws, Khondaker Miraz Rahman (7870067), Charlotte, Hind, Mark Laws (7870093), Shirin Jamshidi (7870109), Khondaker Miraz, Rahman, J Mark Sutton (7870127), Charlotte Hind (7870105), Andrea Favaron (7870106), Andrea, Favaron, Shirin, Jamshidi, J Mark, Sutton   +11 more
core   +1 more source

High-resolution mapping of fluoroquinolones in TB rabbit lesions reveals specific distribution in immune cell types

eLife, 2018
Understanding the distribution patterns of antibiotics at the site of infection is paramount to selecting adequate drug regimens and developing new antibiotics.
Landry Blanc, Isaac B Daudelin, Brendan K Podell, Pei-Yu Chen, Matthew Zimmerman, Amanda J Martinot, Rada M Savic, Brendan Prideaux, Véronique Dartois   +8 more
doaj   +1 more source

Achromobacter : mechanisms of acquired resistance to fluoroquinolones

, 2022
Achromobacter est un pathogène opportuniste émergent, rencontré principalement chez les patients atteints de mucoviscidose. Ce sont des bacilles à Gram négatif non fermentaires présentant des résistances naturelles à de nombreux antibiotiques ainsi que ...
Magallon, Arnaud
core  

Fluoroquinolone-resistant Escherichia coli strains in animal and poultry feed from Ukrainian feed-producing enterprises

Біологія тварин
The article presents the results of studying the sensitivity of Escherichia coli strains isolated from animal and poultry feed samples to fluoroquinolones of the second (ofloxacin, norfloxacin), third (levofloxacin) and fourth (moxifloxacin) generations.
N. V. Kuryata, O. M. Chechet, O. I. Gorbatyuk, O. V. Pishchanskyi, L. V. Balanchuk, N. Y. Mekh, O. M. Zhovnir   +6 more
doaj   +1 more source

Healthcare associated Clostridioides difficile infection in adult surgical and medical patients hospitalized in tertiary hospital in Belgrade, Serbia: a seven years prospective cohort study

Libyan Journal of Medicine, 2020
Introduction: Clostridioides difficile (C. difficile) infection (CDI) is one of the most common healthcare-associated (HA) infections in contemporary medicine.
Vesna Šuljagić, Bojana Milenković, Aneta Perić, Dragutin Jovanović, Vesna Begović-Kuprešanin, Srđan Starčević, Aleksandar Tomić, Sandra Vezmar Kovačević, Viktorija Dragojević-Simić   +8 more
doaj   +1 more source

Fluoroquinolones in ambulatory surgical practice: whom, when, how?

Амбулаторная хирургия, 2016
The articLe discusses the indications and conditions for the use of fLuoroquinoLones (ciprofloxacin, LevofLoxacin, moxifLoxacin) in surgicaL infections of the skin and soft tissues in ambuLatory patients.
A. V. Golub, V. G. Pleshkov, V. V. Privol'nev   +2 more
doaj  

Duodenal ulcer promoting gene 1 (dupA1) is associated with A2147G clarithromycin-resistance mutation but not interleukin-8 secretion from gastric mucosa in Iraqi patients

New Microbes and New Infections, 2015
Helicobacter pylori causes peptic ulceration and gastric adenocarcinoma. The aims were to study the influence of dupA1 positivity upon interleukin-8 (IL-8) secretion from gastric mucosa and determine the prevalence of mutations responsible for ...
N.R. Hussein, I. Tunjel, H.S. Majed, S.T. Yousif, S.I. Aswad, M.S. Assafi   +5 more
doaj   +1 more source

Fluoroquinolones for treating typhoid and paratyphoid fever (enteric fever)

, 2008
Background: Fluoroquinolones are recommended as first-line therapy for typhoid and paratyphoid fever (enteric fever), but how they compare with other antibiotics and different fluoroquinolones is unclear.Objectives: To evaluate fluoroquinolone ...
Critchley, Julia A., Azmatullah, Asma, Bhutta, Zulfiqar Ahmed, Anita KM Zaidi, Julia A Critchley, Asma Azmatullah, Zulfiqar A Bhutta, Zaidi, Anita K. M., Madni, Syed Ali, Durrane Thaver, Syed Ali Madni, Thaver, Durrane   +11 more
core   +1 more source

Antimicrobial Drug Prescribing for Pneumonia in Ambulatory Care

Emerging Infectious Diseases, 2005
To determine patterns and predictors of antimicrobial drug use for outpatients with community-acquired pneumonia, we examined office visit and pharmacy claims data of 4 large third-party payer organizations from 2000 to 2002.
Conan MacDougall, B. Joseph Guglielmo, Judy Maselli, Ralph Gonzales   +3 more
doaj   +1 more source

Modelled PNECs for macrolides and fluoroquinolones [55].

, 2019
Modelled PNECs for macrolides and fluoroquinolones [55].
Virginie D. J. Keller (7344653), Andrew C. Singer (7344647), Qiuying Xu (7344650)   +2 more
core   +1 more source