Results 151 to 160 of about 72,300 (203)
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Fluoroquinolones in Paediatrics
Drugs, 1999Fluoroquinolones have a broad spectrum of activity against gram-positive, gram-negative, and mycobacterial organisms as well as anaerobes, Mycoplasma, Chlamydia, Ureaplasma, and Legionella spp. They have excellent oral bioavailability, with good tissue penetration, and long elimination half-lives. The experience with fluoroquinolones in paediatrics has
H S, Jafri, G H, McCracken
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Ophthalmology, 2009
To report a possible association between fluoroquinolones and diplopia.Database study.A total of 171 subjects were studied.Spontaneous reports from the National Registry of Drug-Induced Ocular Side Effects, World Health Organization, and Food and Drug Administration were collected on fluoroquinolones and diplopia.Data garnered from the spontaneous ...
Frederick W, Fraunfelder +1 more
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To report a possible association between fluoroquinolones and diplopia.Database study.A total of 171 subjects were studied.Spontaneous reports from the National Registry of Drug-Induced Ocular Side Effects, World Health Organization, and Food and Drug Administration were collected on fluoroquinolones and diplopia.Data garnered from the spontaneous ...
Frederick W, Fraunfelder +1 more
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Fluoroquinolones and tuberculosis
Expert Opinion on Investigational Drugs, 2002Tuberculosis (TB) remains one of the main causes of morbidity worldwide, and the emergence of multi-drug resistant (MDR) Mycobacterium tuberculosis strains in some parts of the world has become a major concern. The decrease in activity of the major anti-TB drugs, such as isoniazid and rifampicin, is an important threat and alternative therapies are ...
André, Bryskier, John, Lowther
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Fluoroquinolones in Paediatrics
Paediatric Drugs, 2001The fluoroquinolones are an important group of antibiotics, which are widely used in adult patients because of their high penetration in tissues and bactericidal activity. However, they are not licensed for paediatric use (except the limited indication of Pseudomonas infection in cystic fibrosis) because of their potential to cause joint toxicity ...
D, Gendrel, F, Moulin
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Dysglycaemias and Fluoroquinolones
Drug Safety, 2008The fluoroquinolones are an extremely popular class of antibacterials, owing to their broad spectrum of activity and the convenience of their intravenous and oral dosage formulations. Overall, the currently available fluoroquinolones have a good safety profile; however, certain fluoroquinolones within the class have been associated with severe and life-
Roshan J, Lewis, John F, Mohr
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The fluoroquinolones - reappraisal
International Journal of Antimicrobial Agents, 1992The fluoroquinolones (FQ) still appear to draw major interest despite the fact that they have already been used for about a decade. The International Journal of Antimicrobial Agents has published four extensive reviews on norfloxacin, pefloxacin, ciprofloxacin, ofloxacin in its recent issues; two thirds of the pages of the first issue of the journal ...
E, Rubinstein, C, Carbon
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Infectious Disease Clinics of North America, 1995
Since the introduction of the floroquinolones for clinical use in the late 1980s, they have been used successfully for a large number of clinical situations. As experience accumulates, the indications and optimal use of these agents gradually become more clear.
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Since the introduction of the floroquinolones for clinical use in the late 1980s, they have been used successfully for a large number of clinical situations. As experience accumulates, the indications and optimal use of these agents gradually become more clear.
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Mayo Clinic Proceedings, 1999
The quinolones are broad-spectrum antibacterial agents that have a novel mechanism of action. As synthetic compounds, these agents have been developed extensively to optimize antimicrobial activity, pharmacokinetic properties, and drug safety. Although earlier quinolones were effective only in the genitourinary and gastrointestinal tracts and only had ...
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The quinolones are broad-spectrum antibacterial agents that have a novel mechanism of action. As synthetic compounds, these agents have been developed extensively to optimize antimicrobial activity, pharmacokinetic properties, and drug safety. Although earlier quinolones were effective only in the genitourinary and gastrointestinal tracts and only had ...
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Infectious Disease Clinics of North America, 2004
This article discusses the newer fluoroquinolones in detail with respect to their pharmacokinetics, pharmacodynamics, safety, and spectrum of in vitro activity. The newer agents are compared and contrasted with the older ones, particularly ciprofloxacin.
Judith A, O'Donnell, Steven P, Gelone
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This article discusses the newer fluoroquinolones in detail with respect to their pharmacokinetics, pharmacodynamics, safety, and spectrum of in vitro activity. The newer agents are compared and contrasted with the older ones, particularly ciprofloxacin.
Judith A, O'Donnell, Steven P, Gelone
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Photophysics and photochemistry of fluoroquinolones
Chemical Society Reviews, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
A Albini, S Monti
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